Linking Magnetic Fe3O4 Nanoparticles to Poly (ԑ-caprolactone) via Cyanuric Chloride, Investigation of Thermal and Magnetic Properties

Öz

In this study, firstly poly (ԑ-caprolactone) (PCL) was synthesized by ring opening polymerization. Next, cyanuric chloride (CC) was bonded to PCL and modified by magnetic Fe3O4 nanoparticles capped with 3-aminopropyl trimethoxysilane. Synthesized polymers were characterized by FT-IR, 1H-NMR ve 13C-NMR. Thermal datas showed that thermal stability of a-MNP decreased after bonded to (PCL-g-CC). It was determined from the vibrating sample magnetometer (VSM) measurements that the saturation magnetization (Ms) of a-MNP and PCL-g-CC-g-(a-MNP)] were 52.07 emug-1 and 32.08 emug-1. Additionally, particle sizes of a-MNP and [PCL-g-CC-g-(a-MNP)] was calculated 15.98 nm and 21.41 nm, respectively. While determining that a-MNP was trapped in the polymer in the SEM image of [PCL-g-CC-g-(a-MNP)], the Fe atom seen in the EDX data proves that there was MNP in the structure.

Anahtar Kelimeler

• SEM
• ԑ-caprolactone
• cyanuric chloride
• nanoparticle
• magnetization

Proje Numarası

FF.15.11

Manyetik Fe3O4 Nanopartiküllerinin Siyanurik Klorür Yoluyla Poli (ԑ-Kaprolakton)’ a Bağlanması, Termal ve Manyetik Özelliklerinin İncelenmesi

Öz

Bu çalışmada öncelikle halka açılma polimerizasyon yöntemiyle poli (ԑ-kaprolakton) (PCL) sentezlendi. Ardından PCL’ ye siyanürik klorür (CC) bileşiği bağlandı ve 3-aminopropil trimetoksisilan ile kaplanmış manyetik Fe3O4 nanopartikülleri (MNP) ile modifiye edildi. Sentezlenen polimerlerin karekterizasyonu FT-IR, 1H-NMR ve 13C-NMR ile yapıldı. Termal veriler a-MNP’ nin termal kararlılığının (PCL-g-CC) bağlandıktan sonra düştüğünü gösterdi. Titreşimli numune manyetometre (VSM) ölçümlerinden (a-MNP)’ nin doygunluk manyetizasyon değeri (Ms) 52.07 emug-1 ve [PCL-g-CC-g-(a-MNP)]’ nin Ms değerinin ise 32.08 emug-1 olduğu belirlendi. Ayrıca VSM ölçümlerinden partikül boyutları a-MNP ve [PCL-g-CC-g-(a-MNP)] için sırasıyla 15.98 nm ve 21.41 nm olarak hesaplandı. [PCL-g-CC-g-(a-MNP)] SEM görüntüsünde a-MNP’ nin polimer içerisinde hapsolduğu belirlenirken, EDX verilerinde görülen Fe atomu, yapıda MNP’ nin olduğunu kanıtlar niteliktedir.

Anahtar Kelimeler

• ԑ-kaprolakton
• siyanurik klorür
• nanopartikül
• manyetizasyon
• SEM

Destekleyen Kurum

Fırat Üniversitesi

Proje Numarası

FF.15.11

Kaynakça

1. Blotny G, 2006. Recent applications of 2, 4, 6-trichloro-1, 3, 5-triazine and its derivatives in organic synthesis. Tetrahedron, 62 (41): 9507-9522.
2. Burke NA, Stöver HD, Dawson FP, 2002. Magnetic nanocomposites: preparation and characterization of polymer-coated iron nanoparticles. Chemistry of Materials, 14 (11): 4752-4761.
3. Chang M, Matuszko A. (1962). Synthesis and Properties of Some Cyanuric Chloride Derivatives: Bureau Of Naval Weapons Washington DC.
4. Kalkan NA, Aksoy S, Aksoy EA, Hasirci N, 2012. Preparation of chitosan‐coated magnetite nanoparticles and application for immobilization of laccase. Journal of Applied Polymer Science, 123 (2): 707-716.
5. Kommareddi NS, Tata M, John VT, McPherson GL, Herman MF, Lee Y-S ve Kaplan DL, 1996. Synthesis of superparamagnetic polymer− ferrite composites using surfactant microstructures. Chemistry of Materials, 8 (3): 801-809.
6. Kumar R, Gupta L, Pal P, Khan S, Singh N, Katiyar SB ve Kanaujiya JK, 2010. Synthesis and cytotoxicity evaluation of (tetrahydro-β-carboline)-1, 3, 5-triazine hybrids as anticancer agents. European journal of medicinal chemistry, 45 (6): 2265-2276.
7. Ma X, Tan S-T, Khoo C-L, Sim H-M, Chan L-W, Chui W-K, 2011. Synthesis and antimicrobial activity of N1-benzyl or N1-benzyloxy-1, 6-dihydro-1, 3, 5-triazine-2, 4-diamines. Bioorganic & medicinal chemistry letters, 21 (18): 5428-5431.
8. Pekdemir ME. (2019). Manyetik nanotanecikler üzerinde modifikasyon çalışmaları (Doktora Tezi), Fırat Üniversitesi, Fen Bilimleri Enstitüsü.

9. Pekdemir ME, Ertürkan D, Külah H, Boyacı İH, Özgen C, Tamer U, 2012. Ultrasensitive and selective homogeneous sandwich immunoassay detection by Surface Enhanced Raman Scattering (SERS). Analyst, 137 (20): 4834-4840.
10. Popiołek Ł, Baran I, 2015. Synthesis of New Cyanuric Chloride Derivatives. International Research Journal of Pure and Applied Chemistry1-6.
11. Seckin T, Vural S, Köytepe S, 2010. Preparation and structural properties of Fe 3 O 4–polyimide hybrid nanocomposites. Polymer bulletin, 64 (2): 115.
12. Soozanipour A, Taheri-Kafrani A, Barkhori M, Nasrollahzadeh M, 2019. Preparation of a stable and robust nanobiocatalyst by efficiently immobilizing of pectinase onto cyanuric chloride-functionalized chitosan grafted magnetic nanoparticles. Journal of colloid and interface science, 536 261-270.
13. Soozanipour A, Taheri-Kafrani A, Isfahani AL, 2015. Covalent attachment of xylanase on functionalized magnetic nanoparticles and determination of its activity and stability. Chemical Engineering Journal, 270 235-243.
14. Wang Q, Liu G, Shao R, Huang R, 2003. Synthesis and antivirus activity of 1, 3, 5‐triazine derivatives. Heteroatom Chemistry: An International Journal of Main Group Elements, 14 (6): 542-545.
15. Xie J, Xu C, Xu Z, Hou Y, Young KL, Wang S ve Sun S, 2006. Linking hydrophilic macromolecules to monodisperse magnetite (Fe3O4) nanoparticles via trichloro-s-triazine. Chemistry of Materials, 18 (23): 5401-5403.
16. Yaacob II, Nunes AC, Bose A, 1995. Magnetic nanoparticles produced in spontaneous cationic-anionic vesicles: room temperature synthesis and characterization. Journal of colloid and interface science, 171 (1): 73-84.