Investigation of Changes Against Time in the Artificial Gastric Liquid Medium of Pesticide Active Substances

Öz

In this study, grown tomato samples were examined changes of pesticide active substances by two different methods in the artificial gastric liquid (AGL) medium prepared. In the first method, Trifloxystrobin and Imidacloprid pesticide active substances were sprayed on the tomato samples before the harvest period. Time-dependent change of the active substance of Trifloxystrobin; although initially 83.17 ng g-1, it was determined as 24.71 ng g-1 in 240 min. The concentration of this active substance was determined that decreased with time and the % change was 70.29. While Imidacloprid active substance initially was 10.20 ng g-1, it was determined as 10.32 ng g-1 at 240 min. It was determined that this active substance did not change between the first and the last concentration depending on the time. In the second method, 75 pesticide active substances were spiked to the tomato sample and the time-dependent change in the AGL medium was examined. The concentration of 10 active substances that above 70% of the change rate was determined that there was a statistical decrease depending on the time % changes in the range between 0-240 min. The concentration of 30 active substances in below 70% of the change rate was determined that did not a statistical decrease as depending on time. however, % changes were observed that there was a certain thought at different rates between the first and the last concentration after 240 min. The last 15 active substances 240 min concentrations were determined that increased of % changes compared to 0 min.

Anahtar Kelimeler

• Pesticide
• tomato
• LC-MS/MS
• GC-MS/MS
• AGL medium

Kaynakça

1. Algharibeh GR, AlFararjeh MS, 2019. Pesticide residues in fruits and vegetables in Jordan using liquid chromatography/tandem mass spectrometry. Food Additives and Contaminants: Part B Surveillance, 12: 65–73. https://doi.org/10.1080/19393210.2018.1548505
2. An X, Wu S, Guan W, Lv L, Liu X, Zhang W, Cai L, 2018. Effects of different protective clothing for reducing body exposure to chlorothalonil during application in cucumber greenhouses. Human and Ecological Risk Assessment, 24: 14–25. https://doi.org/10.1080/10807039.2017.1349540
3. Arias N, Arazuri S, Jarén C, 2013. Ability of NIRS technology to determine pesticides in liquid samples at maximum residue levels. Pest Management Science, 69: 471–477. https://doi.org/10.1002/ps.3392
4. Calvo H, Redondo D, Remón S, Venturini ME, Arias E, 2019. Efficacy of electrolyzed water, chlorine dioxide and photocatalysis for disinfection and removal of pesticide residues from stone fruit. Postharvest Biology and Technology, 148: 22–31. https://doi.org/10.1016/j.postharvbio.2018.10.009
5. Diop A, Diop YM, Thiaré DD, Cazierc F, Sarra OS, Kasprowiake A, Landy D, Delattre F, 2016. Monitoring survey of the use patterns and pesticide residues on vegetables in the Niayeszone, Senegal. Chemosphere, 144: 1715–1721.
6. Elmastas A, 2018. Yaş meyve sebze ürünlerinin çeşitli koşullarda pestisit kalıntılarının LC-MS/MS ve GC-MS/MS ile analizlerinin kantitatif tayini, Dicle Üniversitesi Fen Bilimleri Enstitüsü, Doktora Tezi (Basılmış).
7. Farajzadeh MA, Sohrabi H, Mohebbi A, 2019. Combination of modified QuEChERS extraction method and dispersive liquid–liquid microextraction as an efficient sample preparation approach for extraction and preconcentration of pesticides from fruit and vegetable samples. Food Analytical Methods, 12: 534–543. https://doi.org/10.1007/s12161-018-1384-x
8. Farajzadeh, MA, Sohrabi H, Mohebbi A, Mogaddam MRA, 2019. Combination of a modified quick, easy, cheap, efficient, rugged, and safe extraction method with a deep eutectic solvent based microwave-assisted dispersive liquid–liquid microextraction: Application in extraction and preconcentration of multiclass pestic. Journal of Separation Science, 42: 1273–1280. https://doi.org/10.1002/jssc.201801107

9. Galia E, Nicolaides E, Hörter D, Löbenberg R, Reppas C, Dressman JB, 1998. Evaluation of various dissolution media for predicting in vivo performance of class I and II drugs. Pharmaceutical Research, 15: 698-705.
10. Hou J, Zhang Q, Zhou Y, Ahammed GJ, Zhou Y, Yu J, Xia X, 2018. Glutaredoxin GRXS16 mediates brassinosteroid-induced apoplastic H2O2 production to promote pesticide metabolism in tomato. Environmental Pollution, 240: 227–234. https://doi.org/10.1016/j.envpol.2018.04.120
11. Jara EA, Winter CK, 2019. Safety levels for organophosphate pesticide residues on fruits, vegetables, and nuts. International Journal of Food Contamination, 6: 2–8. https://doi.org/10.1186/s40550-019-0076-7
12. Kapsi M, Tsoutsi C, Paschalidou A, Albanis T, 2019. Environmental monitoring and risk assessment of pesticide residues in surface waters of the Louros River (N.W. Greece). Science of the Total Environment, 650: 2188–2198. https://doi.org/10.1016/j.scitotenv.2018.09.185
13. Lehotay SJ, 2019. Possibilities and limitations of isocratic fast liquid chromatography-tandem mass spectrometry analysis of pesticide residues in fruits and vegetables. Chromatographia, 82: 235–250. https://doi.org/10.1007/s10337-018-3595-0
14. Ersoy N, Tekinarslan O, Akcay E, Ulas O, 2019. Determination of pesticide residues in apricot (Prunus armeniaca L.) grown determination of pesticide residues in apricot (Prunus armeniaca L.) grown at good agricultural practices (GAPs) by LC-MS/MS and GC-MS. Erwerbs-Obstbau, 60: 49–358. https://doi.org/10.1007/s10341-018-0383-9
15. Song NE, Lee JY, Mansur AR, Jang HW, Lim MC, Lee Y, Nam TG, 2019. Determination of 60 pesticides in hen eggs using the QuEChERS procedure followed by LC-MS/MS and GC-MS/MS. Food Chemistry, 298: 125050. https://doi.org/10.1016/j.foodchem.2019.125050
16. Türkoz Bakırcı G, Yaman Acay DB, Bakırcı F, Ötleş S 2014. Pesticide residues in fruits and vegetables from the aegean region. Turkey Food Chemistry, 160: 379–392.
17. Wei J, Chen Y, Tiemur A, Wang J, Wu B, 2018. Degradation of pesticide residues by gaseous chlorine dioxide on table grapes. Postharvest Biology and Technology, 137: 142–148. https://doi.org/10.1016/j.postharvbio.2017.12.001
18. Wu ML, Wu YC, Chen YC, 2019. Detection of pesticide residues on intact tomatoes by carbon fiber ionization mass spectrometry. Analytical and Bioanalytical Chemistry, 411: 1095–1105. https://doi.org/10.1007/s00216-018-1539-z
19. Zawiyah S, Che Man YB, Nazimah SAH, Chin CK, Tsukamoto I, Hamanyza AH, Norhaizan I, 2007. Determination of organo chlorine and pyrethroid pesticides in fruitand vegetables using SAX/PSA clean-upcolumn. Food Chemistry, 102: 98–103.
20. Zengin E, Karaca İ, 2017. Uşak ilinde örtü altı üretimi yapılan domateslerdeki pestisit kalıntılarının belirlenmesi. Süleyman Demirel Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 21: 554-559.