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Effectivity Analysis of the Decontamination Products for Radioactive Materials Used in Nuclear Medicine

Year 2016, Volume: 6 Issue: 2, 59 - 69, 30.06.2016

Abstract

In this study, several decontamination products were analysed in terms of their effciency in
decontaminating the radioactives
99mTc, 18F-DG, 131I and201Tl from contaminated surfaces. Furthermore, the
performance of existing commercial washers was examined and it was observed that it was far from the desired
levels. Also, it was determined that the temperature and pH were the most important factors in the decontamination
process of
99mTc where as alcohol had no effect. Based on the performed analysis, it was concluded that the most
effective decontamination product was DM-D (Decontamination Material-D) for
99mTc, 18F-DG, 131I and 201Tl.
Effectiveness analysis of DM-D for
99mTc contamination on various surfaces showed that decontamination was
quite fast on scrubsand formica and that DM-D was very effective on skin but not on plastic floor covering material.
The effectiveness of various molecular groups in the decontaminant was also investigated. As a result, the acetate
group was observed as the most effective component of the decontaminant
  

References

  • Alfassi ZB, Groppi F, Bonardi ML, Goeij JJM de, 2005. On the ‘‘artifcial’’ nature of Tc and the ‘‘carrier-free’’ nature of 99mTc from 9Mo/99mTc generators. Appl. Radiat. Isotopes. 63, 37–40.
  • Atkins PW, 2010. Physical Chemistry, Oxford Universty Pres, 9 Edition.
  • Beyhan M, 2003. Atık çamurlar v edoğal malzemeler ile sulardan florüriyonu gideriminin araştırılması, Doktora, YTÜ, Fen BilimleriEnstitüsü, İstanbul
  • Görpe A., Cantez S, 1992. Pratik Nükleer Tıp, İstanbul Tıp FakültesiVakfı, İstanbul, pp.1–42.
  • Eroglu H, Yapıcı S, Nuhoglu C, Varoglu E, 2009. An environmentally friendly process; adsorption of radionuclide Tl-201 on fbrous waste tea, J. Hazard.Mater 163, 607–617.
  • Kocher DC, 1981. Radioactive Decay Tablets, Technical Information Center, U.S. Department of Energy, DOE/TIC 11026, Washington, DC.
  • Kowalsky RJ, Falen SW, 2011. Radiopharmaceuticals in Nuclear Medicine Practice, American Pharmacists Association, 109- 127.
  • Saha GB, 2010. Fundamentals of Nuclear Pharmacy. Springer- Verlag, New York, Sixth Edution.
  • Sampson CB, 1999. Textbook of Radiopharmacy Theory and Practice, Gordon and Breach Science Publishers, pp. 125–244.
  • Smith JM, 1981. Chemical Engineering Kinetics, Mc- Graw- Hill İnternational Book London.

Nükleer Tıpta Kullanılan Radyoaktif Materyaller için Dekontaminasyon Ürünlerinin Etkinliğinin Analizi

Year 2016, Volume: 6 Issue: 2, 59 - 69, 30.06.2016

Abstract

Bu çalışmada, radyoaktif Tc-99m, F-18-DG, I-131 ve Tl-201 ile kontamine olmuş yüzeylerin
dekontaminasyonu için birçok dekontaminasyon malzemesinin etkinliği analiz edildi. Ayrıca mevcut ticari
radyoaktivif temizleyicilerin performansları incelendi ve bunların beklenilen seviyelerden uzak olduğu gözlemlendi.
Yine, yapılan çalışmalar sonucunda dekontaminasyon üzerine alkolün etkisinin olmadığı, sıcaklığın ve pH’ın ise
Tc-99m’in dekontaminasyon sürecinde önemli faktörler olduğu belirlendi. Yapılan analizler ışığında, Tc-99m,
F-18-DG, I-131 ve Tl-201 için en etkili dekontaminasyon ürününün DM-D (Dekontaminasyon materyal-D) olduğu
sonucuna varıldı. Tc-99m ile kontamine olmuş çeşitli yüzeylerdeki DM-D’nin etkinlik analizi dekontaminasyonun
formika ve giysiler üzerinde oldukça hızlı olduğunu ve DM-D’nin deri üzerinde çok etkili olduğunu ancak kaplama
materyali plastik olan zemin üzerinde hiçbir etkisinin olmadığını gösterdi. Ayrıca, dekontaminasyondaki çeşitli
moleküler grupların etkinliği incelendi. Sonuç olarak, asetat grubunun dekontaminasyonda en etkili komponent
olduğu gözlemlendi.
  

References

  • Alfassi ZB, Groppi F, Bonardi ML, Goeij JJM de, 2005. On the ‘‘artifcial’’ nature of Tc and the ‘‘carrier-free’’ nature of 99mTc from 9Mo/99mTc generators. Appl. Radiat. Isotopes. 63, 37–40.
  • Atkins PW, 2010. Physical Chemistry, Oxford Universty Pres, 9 Edition.
  • Beyhan M, 2003. Atık çamurlar v edoğal malzemeler ile sulardan florüriyonu gideriminin araştırılması, Doktora, YTÜ, Fen BilimleriEnstitüsü, İstanbul
  • Görpe A., Cantez S, 1992. Pratik Nükleer Tıp, İstanbul Tıp FakültesiVakfı, İstanbul, pp.1–42.
  • Eroglu H, Yapıcı S, Nuhoglu C, Varoglu E, 2009. An environmentally friendly process; adsorption of radionuclide Tl-201 on fbrous waste tea, J. Hazard.Mater 163, 607–617.
  • Kocher DC, 1981. Radioactive Decay Tablets, Technical Information Center, U.S. Department of Energy, DOE/TIC 11026, Washington, DC.
  • Kowalsky RJ, Falen SW, 2011. Radiopharmaceuticals in Nuclear Medicine Practice, American Pharmacists Association, 109- 127.
  • Saha GB, 2010. Fundamentals of Nuclear Pharmacy. Springer- Verlag, New York, Sixth Edution.
  • Sampson CB, 1999. Textbook of Radiopharmacy Theory and Practice, Gordon and Breach Science Publishers, pp. 125–244.
  • Smith JM, 1981. Chemical Engineering Kinetics, Mc- Graw- Hill İnternational Book London.
There are 10 citations in total.

Details

Journal Section Biyomedikal Mühendisliği / Biomedical Engineering
Authors

Hayrettin Eroğlu

Oğuz Aksakal This is me

Publication Date June 30, 2016
Submission Date January 21, 2016
Acceptance Date February 12, 2016
Published in Issue Year 2016 Volume: 6 Issue: 2

Cite

APA Eroğlu, H., & Aksakal, O. (2016). Effectivity Analysis of the Decontamination Products for Radioactive Materials Used in Nuclear Medicine. Journal of the Institute of Science and Technology, 6(2), 59-69.
AMA Eroğlu H, Aksakal O. Effectivity Analysis of the Decontamination Products for Radioactive Materials Used in Nuclear Medicine. J. Inst. Sci. and Tech. June 2016;6(2):59-69.
Chicago Eroğlu, Hayrettin, and Oğuz Aksakal. “Effectivity Analysis of the Decontamination Products for Radioactive Materials Used in Nuclear Medicine”. Journal of the Institute of Science and Technology 6, no. 2 (June 2016): 59-69.
EndNote Eroğlu H, Aksakal O (June 1, 2016) Effectivity Analysis of the Decontamination Products for Radioactive Materials Used in Nuclear Medicine. Journal of the Institute of Science and Technology 6 2 59–69.
IEEE H. Eroğlu and O. Aksakal, “Effectivity Analysis of the Decontamination Products for Radioactive Materials Used in Nuclear Medicine”, J. Inst. Sci. and Tech., vol. 6, no. 2, pp. 59–69, 2016.
ISNAD Eroğlu, Hayrettin - Aksakal, Oğuz. “Effectivity Analysis of the Decontamination Products for Radioactive Materials Used in Nuclear Medicine”. Journal of the Institute of Science and Technology 6/2 (June 2016), 59-69.
JAMA Eroğlu H, Aksakal O. Effectivity Analysis of the Decontamination Products for Radioactive Materials Used in Nuclear Medicine. J. Inst. Sci. and Tech. 2016;6:59–69.
MLA Eroğlu, Hayrettin and Oğuz Aksakal. “Effectivity Analysis of the Decontamination Products for Radioactive Materials Used in Nuclear Medicine”. Journal of the Institute of Science and Technology, vol. 6, no. 2, 2016, pp. 59-69.
Vancouver Eroğlu H, Aksakal O. Effectivity Analysis of the Decontamination Products for Radioactive Materials Used in Nuclear Medicine. J. Inst. Sci. and Tech. 2016;6(2):59-6.