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Determination of Bioactive Properties of Alcohol Extracts of Types of Pleurotus sajor-caju and Pleurotus ostreatus

Yıl 2021, Cilt 11, Sayı 3, 1734 - 1741, 01.09.2021
https://doi.org/10.21597/jist.828653

Öz

In this study, alcohol extracts of Pleurotus sajor-caju and Pleurotus ostreatus which are edible mushroom species were obtained and their extract contents were determined by GC-MS. Antioxidant content of these alcohol extracts were determined with 2-2-diphenyl, 1-picrylhydrazyl (DPPH). Antimicrobial activity of alcohol extracts were determined on Klebsiella oxycota, Pseudomonas aeruginosa, Staphylococcus aureus, Corynobacterium diphtheria, Enterococcus faecalis, Escherichia coli, Serratia marcescens, Bacillus cereus and Bacillus thuringiensis bacteria, and Rhodotorula glutinis and Candida albicans yeasts. Moreover, this study indicated the anti-quorum sensing activity of the tested mushroom extracts against Chromobacterium violaceum CV026. P. sajor-caju and P. ostreatus alcohol extract compositions were determined with GC-MS. According to GC-MS results, 20 different compounds were found in P. sajor-caju and P. ostreatus alcohol extract. Hexadeconoic acid, linoleic acid, octadecanolacid,2,3-dihydroxypropyl ester and palmitic acid were found in both mushroom extracts. Because they contain a high content of fatty acids, alcohols, aldehydes, ketones and terpenoids, these extracts can be used both as antimicrobial, anticancerogenic, antioxidant and antiaging agents or can be consumed as a food supplements.

Kaynakça

  • Aisya B, Naveen T, Pravalika K, Haritha G, Anusha K, 2010.Treatment of cancer by medicinal mushrooms. Int. J. Pharm. Technol. 2:102-117.
  • Akyuz M, Onganer AN, Erecevıt P, Kirbag S, 2010. Antimicrobial activity of some edible mushrooms in the eastern and southeast Anatolia region of Turkey. GU J. Sci. 23(2):125-130.
  • Alam N, Yoon KN, Lee TS, 2011a. Evaluation of the antioxidant and antityrosinase activities of three extracts from Pleurotus nebrodensis fruiting bodies. Afr. J. Biotechnol. 10:2978–2986.
  • Alam N, Yoon KN, Cha YJ, Kim JH, Lee KR, Lee TS, 2011b. Appraisal of the antioxidant, phenolic compounds concentration, xanthine oxidase and tyrosinase inhibitory activities of Pleurotus salmoneostramineus. Afr. J. Agric. Res. 6: 1555–1563.
  • Alves MJ, Ferreira IC, Dias J, Teixeira V, Martins A, Pintado M, 2012. A review on antimicrobial activity of mushroom (Basidiomycetes) extracts and isolated compounds. Planta Med. 78:1707-1718.
  • Avci E, Avcı G, Kose DA, 2014, Determination of Antioxidant and Antimicrobial Activities of Medically Important Mushrooms Using Different Solvents and Chemical Composition via GC/MS Analyses. J Food Nutr Res. 2:429-434.
  • Bauer AW, Kirby WMM, Sherris JC, Turck M, 1966. Antibiotic susceptibility testing by a standardized single disk method. Am J Clin Pathol 45: 493-496.
  • Cilerdzic J, Stajic M, Vukojevic J, Milovanovic I, Muzgonja N, 2015. Antioxidant and antifungal potential of Pleurotus ostreatus and Agrocybe cylindracea basidiocarps and mycelia. Curr Pharm Biotechnol. 16:179-186.
  • Corrêa RCG, de Souza, AH, Calhelha RC, Barros, L, Glamoclija J, Sokovic M, Peralta RM, Bracht A, Ferreira ICFR, 2015. Bioactive formulations prepared from fruiting bodies and submerged culture mycelia of the Brazilian edible mushroom Pleurotus ostreatoroseus Singer. Food Funct. 6:2155-2164.
  • Geyikoglu F, Cerig S, Ozdal M, Koc K, Algur OF, Yildiz GD, Gulmez O, 2017. Toxicological evaluation of submerged liquid culture from Phanerochaete chrysosporium mycelium on human blood cells: cytotoxicity, genotoxicity and oxidative damage. Int. J. Sec. Metab. 4:319-329.
  • Guo T, Wei L, Sun J, Hou CL, Fan L, 2011. Antioxidant activities of extract and fractions from tuber indicum cooke and massee. Food Chem. 127:1634–1640.
  • Hong-Ji L, Hai-Yan C, Lin-Lin F, Zhi-Hua J, Qi-He C, Ying-Chun J, 2016. In Vitro Antioxidant Activities and in Vivo Anti-Hypoxic Activity of the Edible Mushroom Agaricus bisporus (Lange) Sing. Chaidam. Molecules 20:17775-17788.
  • Kozarski M, Klaus A, Niksic M, Jakovljevic D, Helsper JP, Van Griensven LJ, 2011. Antioxidative and immunomodulating activities of polysaccharide extracts of the medicinal mushrooms Agaricus bisporus, Agaricus brasiliensis, Ganoderma lucidum and Phellinus linteus. Food Chem. 129:1667-1675.
  • Li B, Lu F, Suo X, Nan H, Li B, 2010. Antioxidant properties of cap and stipe from Coprinus comatus. Molecules 15:1473-1486.
  • Mulya E, Waturangi DE, 2021. Screening and quantification of anti-quorum sensing and antibiofilm activity of Actinomycetes isolates against food spoilage biofilm-forming bacteria. BMC Microbiology, 21(1), 1-8.
  • Muna GA, John M, Benson M, Ogoyi D, 2015. Antioxidant properties of cultivated edible mushroom (Agaricus bisporus) in Kenya. Afr. J. Biotechnol. 14:1401-1408.
  • Ozdal M (2018). Determination of carbon and nitrogen sources for the production of mycelial biomass and exopolysaccharide by Lepista nuda in liquid culture. Turkish Journal of Agriculture-Food Science and Technology, 6(5), 581-585.
  • Ozdal M, Gülmez Ö, Özdal ÖG, Algur ÖF, 2019. Antibacterial and Antioxidant Activity of Mycelial Extracts of Different Pleurotus Species. Food Health 5(1): 12-18.
  • Patel S, Goyal A, 2012. Recent developments in mushrooms as anti-cancer therapeutics: a review. 3 Biotech 2(1):1-15. -15.
  • Rathee S, Rathee D, Rathee D, Kumar V, Rathee P, 2012. Mushrooms as therapeutic agents. Rev Bras Farmacogn. 22: 459-474.
  • Reis FS, Martins A, Barros L, Ferreira ICFR, 2012. Antioxidant properties and phenolic profile of the most widely appreciated cultivated mushrooms: A comparative study between in vivo and in vitro samples. Food Chem Toxicol. 50: 1201–1207.
  • Rezaeian S, Saadatmand S, Sattari TN, Mirshamsi, A, 2016. Antioxidant potential and other medicinal properties of edible mushrooms naturally grown in Iran. Biomed. Res. 27:240-247.
  • Singh S, Wang H, Chan Y, Pan W, Dan X, Yin C, Ng. T, 2015. Lectins from edible mushrooms. Molecules 20(1):446-469.
  • Smith Helen, Doyle Sean, Murphy Richard 2015. Filamentous fungi as a source of natural antioxidants. Food Chem. 185: 389-397.
  • Vamanu Emanuel, 2012. In vitro antimicrobial and antioxidant activities of ethanolic extract of lyophilized mycelium of Pleurotus ostreatus PQMZ91109. Molecules 17:3653-3671.
  • Glamoclija J, Ciric A, Nikolic M, Fernandes A, Barros L, Calhelha RC, Ferreira, ICFR, Sokovic M, van Griensven LJLD, 2015. Chemical characterization and biological activity of Chaga (Inonotus obliquus), a medicinal “mushroom”. J. Ethnopharmacol. 162: 323–332.
  • Strapáč I, Bedlovičová Z, Čuvalová A, Handrova L, Kmeť V, 2019. Antioxidant and anti-quorum sensing properties of edible mushrooms. Journal of Food & Nutrition Research, 58(2), 146-152.
  • Soković M, Ćirić A, Glamočlija J, Nikolić M, & van Griensven, L, 2014. Agaricus blazei hot water extract shows anti quorum sensing activity in the nosocomial human pathogen Pseudomonas aeruginosa. Molecules, 19(4): 4189-4199.

Determination of Chemical Constituents and Bioactive Properties of Alcohol Extracts of Pleurotus sajor-caju and Pleurotus ostreatus

Yıl 2021, Cilt 11, Sayı 3, 1734 - 1741, 01.09.2021
https://doi.org/10.21597/jist.828653

Öz

In this study, alcohol extracts of Pleurotus sajor-caju and Pleurotus ostreatus which are edible mushroom species were obtained and their extract contents were determined by GC-MS. Antioxidant content of these alcohol extracts were determined with 2-2-diphenyl, 1-picrylhydrazyl (DPPH). Antimicrobial activity of alcohol extracts were determined on Klebsiella oxycota, Pseudomonas aeruginosa, Staphylococcus aureus, Corynobacterium diphtheria, Enterococcus faecalis, Escherichia coli, Serratia marcescens, Bacillus cereus and Bacillus thuringiensis bacteria, and Rhodotorula glutinis and Candida albicans yeasts. Moreover, this study indicated the anti-quorum sensing activity of the tested mushroom extracts against Chromobacterium violaceum CV026. P. sajor-caju and P. ostreatus alcohol extract compositions were determined with GC-MS. According to GC-MS results, 20 different compounds were found in P. sajor-caju and P. ostreatus alcohol extract. Hexadeconoic acid, linoleic acid, octadecanolacid,2,3-dihydroxypropyl ester and palmitic acid were found in both mushroom extracts. Because they contain a high content of fatty acids, alcohols, aldehydes, ketones and terpenoids, these extracts can be used both as antimicrobial, anticancerogenic, antioxidant and antiaging agents or can be consumed as a food supplements.

Kaynakça

  • Aisya B, Naveen T, Pravalika K, Haritha G, Anusha K, 2010.Treatment of cancer by medicinal mushrooms. Int. J. Pharm. Technol. 2:102-117.
  • Akyuz M, Onganer AN, Erecevıt P, Kirbag S, 2010. Antimicrobial activity of some edible mushrooms in the eastern and southeast Anatolia region of Turkey. GU J. Sci. 23(2):125-130.
  • Alam N, Yoon KN, Lee TS, 2011a. Evaluation of the antioxidant and antityrosinase activities of three extracts from Pleurotus nebrodensis fruiting bodies. Afr. J. Biotechnol. 10:2978–2986.
  • Alam N, Yoon KN, Cha YJ, Kim JH, Lee KR, Lee TS, 2011b. Appraisal of the antioxidant, phenolic compounds concentration, xanthine oxidase and tyrosinase inhibitory activities of Pleurotus salmoneostramineus. Afr. J. Agric. Res. 6: 1555–1563.
  • Alves MJ, Ferreira IC, Dias J, Teixeira V, Martins A, Pintado M, 2012. A review on antimicrobial activity of mushroom (Basidiomycetes) extracts and isolated compounds. Planta Med. 78:1707-1718.
  • Avci E, Avcı G, Kose DA, 2014, Determination of Antioxidant and Antimicrobial Activities of Medically Important Mushrooms Using Different Solvents and Chemical Composition via GC/MS Analyses. J Food Nutr Res. 2:429-434.
  • Bauer AW, Kirby WMM, Sherris JC, Turck M, 1966. Antibiotic susceptibility testing by a standardized single disk method. Am J Clin Pathol 45: 493-496.
  • Cilerdzic J, Stajic M, Vukojevic J, Milovanovic I, Muzgonja N, 2015. Antioxidant and antifungal potential of Pleurotus ostreatus and Agrocybe cylindracea basidiocarps and mycelia. Curr Pharm Biotechnol. 16:179-186.
  • Corrêa RCG, de Souza, AH, Calhelha RC, Barros, L, Glamoclija J, Sokovic M, Peralta RM, Bracht A, Ferreira ICFR, 2015. Bioactive formulations prepared from fruiting bodies and submerged culture mycelia of the Brazilian edible mushroom Pleurotus ostreatoroseus Singer. Food Funct. 6:2155-2164.
  • Geyikoglu F, Cerig S, Ozdal M, Koc K, Algur OF, Yildiz GD, Gulmez O, 2017. Toxicological evaluation of submerged liquid culture from Phanerochaete chrysosporium mycelium on human blood cells: cytotoxicity, genotoxicity and oxidative damage. Int. J. Sec. Metab. 4:319-329.
  • Guo T, Wei L, Sun J, Hou CL, Fan L, 2011. Antioxidant activities of extract and fractions from tuber indicum cooke and massee. Food Chem. 127:1634–1640.
  • Hong-Ji L, Hai-Yan C, Lin-Lin F, Zhi-Hua J, Qi-He C, Ying-Chun J, 2016. In Vitro Antioxidant Activities and in Vivo Anti-Hypoxic Activity of the Edible Mushroom Agaricus bisporus (Lange) Sing. Chaidam. Molecules 20:17775-17788.
  • Kozarski M, Klaus A, Niksic M, Jakovljevic D, Helsper JP, Van Griensven LJ, 2011. Antioxidative and immunomodulating activities of polysaccharide extracts of the medicinal mushrooms Agaricus bisporus, Agaricus brasiliensis, Ganoderma lucidum and Phellinus linteus. Food Chem. 129:1667-1675.
  • Li B, Lu F, Suo X, Nan H, Li B, 2010. Antioxidant properties of cap and stipe from Coprinus comatus. Molecules 15:1473-1486.
  • Mulya E, Waturangi DE, 2021. Screening and quantification of anti-quorum sensing and antibiofilm activity of Actinomycetes isolates against food spoilage biofilm-forming bacteria. BMC Microbiology, 21(1), 1-8.
  • Muna GA, John M, Benson M, Ogoyi D, 2015. Antioxidant properties of cultivated edible mushroom (Agaricus bisporus) in Kenya. Afr. J. Biotechnol. 14:1401-1408.
  • Ozdal M (2018). Determination of carbon and nitrogen sources for the production of mycelial biomass and exopolysaccharide by Lepista nuda in liquid culture. Turkish Journal of Agriculture-Food Science and Technology, 6(5), 581-585.
  • Ozdal M, Gülmez Ö, Özdal ÖG, Algur ÖF, 2019. Antibacterial and Antioxidant Activity of Mycelial Extracts of Different Pleurotus Species. Food Health 5(1): 12-18.
  • Patel S, Goyal A, 2012. Recent developments in mushrooms as anti-cancer therapeutics: a review. 3 Biotech 2(1):1-15. -15.
  • Rathee S, Rathee D, Rathee D, Kumar V, Rathee P, 2012. Mushrooms as therapeutic agents. Rev Bras Farmacogn. 22: 459-474.
  • Reis FS, Martins A, Barros L, Ferreira ICFR, 2012. Antioxidant properties and phenolic profile of the most widely appreciated cultivated mushrooms: A comparative study between in vivo and in vitro samples. Food Chem Toxicol. 50: 1201–1207.
  • Rezaeian S, Saadatmand S, Sattari TN, Mirshamsi, A, 2016. Antioxidant potential and other medicinal properties of edible mushrooms naturally grown in Iran. Biomed. Res. 27:240-247.
  • Singh S, Wang H, Chan Y, Pan W, Dan X, Yin C, Ng. T, 2015. Lectins from edible mushrooms. Molecules 20(1):446-469.
  • Smith Helen, Doyle Sean, Murphy Richard 2015. Filamentous fungi as a source of natural antioxidants. Food Chem. 185: 389-397.
  • Vamanu Emanuel, 2012. In vitro antimicrobial and antioxidant activities of ethanolic extract of lyophilized mycelium of Pleurotus ostreatus PQMZ91109. Molecules 17:3653-3671.
  • Glamoclija J, Ciric A, Nikolic M, Fernandes A, Barros L, Calhelha RC, Ferreira, ICFR, Sokovic M, van Griensven LJLD, 2015. Chemical characterization and biological activity of Chaga (Inonotus obliquus), a medicinal “mushroom”. J. Ethnopharmacol. 162: 323–332.
  • Strapáč I, Bedlovičová Z, Čuvalová A, Handrova L, Kmeť V, 2019. Antioxidant and anti-quorum sensing properties of edible mushrooms. Journal of Food & Nutrition Research, 58(2), 146-152.
  • Soković M, Ćirić A, Glamočlija J, Nikolić M, & van Griensven, L, 2014. Agaricus blazei hot water extract shows anti quorum sensing activity in the nosocomial human pathogen Pseudomonas aeruginosa. Molecules, 19(4): 4189-4199.

Ayrıntılar

Birincil Dil İngilizce
Konular Biyoloji
Yayınlanma Tarihi Eylül-2021
Bölüm Biyoloji / Biology
Yazarlar

Özlem GÜLMEZ (Sorumlu Yazar)
ATATÜRK ÜNİVERSİTESİ
0000-0002-7199-4634
Türkiye


Murat ÖZDAL
ATATÜRK ÜNİVERSİTESİ, FEN FAKÜLTESİ
0000-0001-8800-1128
Türkiye


Ömer Faruk ALGUR
ATATÜRK ÜNİVERSİTESİ, FEN FAKÜLTESİ
0000-0001-6447-3454
Türkiye


Bilal YİLMAZ
ATATÜRK ÜNİVERSİTESİ, ECZACILIK FAKÜLTESİ, ECZACILIK PR.
0000-0002-8574-7570
Türkiye

Yayımlanma Tarihi 1 Eylül 2021
Başvuru Tarihi 20 Kasım 2020
Kabul Tarihi 4 Haziran 2021
Yayınlandığı Sayı Yıl 2021, Cilt 11, Sayı 3

Kaynak Göster

Bibtex @araştırma makalesi { jist828653, journal = {Journal of the Institute of Science and Technology}, issn = {2146-0574}, eissn = {2536-4618}, address = {}, publisher = {Iğdır Üniversitesi}, year = {2021}, volume = {11}, pages = {1734 - 1741}, doi = {10.21597/jist.828653}, title = {Determination of Chemical Constituents and Bioactive Properties of Alcohol Extracts of Pleurotus sajor-caju and Pleurotus ostreatus}, key = {cite}, author = {Gülmez, Özlem and Özdal, Murat and Algur, Ömer Faruk and Yilmaz, Bilal} }
APA Gülmez, Ö. , Özdal, M. , Algur, Ö. F. & Yilmaz, B. (2021). Determination of Chemical Constituents and Bioactive Properties of Alcohol Extracts of Pleurotus sajor-caju and Pleurotus ostreatus . Journal of the Institute of Science and Technology , 11 (3) , 1734-1741 . DOI: 10.21597/jist.828653
MLA Gülmez, Ö. , Özdal, M. , Algur, Ö. F. , Yilmaz, B. "Determination of Chemical Constituents and Bioactive Properties of Alcohol Extracts of Pleurotus sajor-caju and Pleurotus ostreatus" . Journal of the Institute of Science and Technology 11 (2021 ): 1734-1741 <https://dergipark.org.tr/tr/pub/jist/issue/64410/828653>
Chicago Gülmez, Ö. , Özdal, M. , Algur, Ö. F. , Yilmaz, B. "Determination of Chemical Constituents and Bioactive Properties of Alcohol Extracts of Pleurotus sajor-caju and Pleurotus ostreatus". Journal of the Institute of Science and Technology 11 (2021 ): 1734-1741
RIS TY - JOUR T1 - Determination of Chemical Constituents and Bioactive Properties of Alcohol Extracts of Pleurotus sajor-caju and Pleurotus ostreatus AU - Özlem Gülmez , Murat Özdal , Ömer Faruk Algur , Bilal Yilmaz Y1 - 2021 PY - 2021 N1 - doi: 10.21597/jist.828653 DO - 10.21597/jist.828653 T2 - Journal of the Institute of Science and Technology JF - Journal JO - JOR SP - 1734 EP - 1741 VL - 11 IS - 3 SN - 2146-0574-2536-4618 M3 - doi: 10.21597/jist.828653 UR - https://doi.org/10.21597/jist.828653 Y2 - 2021 ER -
EndNote %0 Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi Determination of Chemical Constituents and Bioactive Properties of Alcohol Extracts of Pleurotus sajor-caju and Pleurotus ostreatus %A Özlem Gülmez , Murat Özdal , Ömer Faruk Algur , Bilal Yilmaz %T Determination of Chemical Constituents and Bioactive Properties of Alcohol Extracts of Pleurotus sajor-caju and Pleurotus ostreatus %D 2021 %J Journal of the Institute of Science and Technology %P 2146-0574-2536-4618 %V 11 %N 3 %R doi: 10.21597/jist.828653 %U 10.21597/jist.828653
ISNAD Gülmez, Özlem , Özdal, Murat , Algur, Ömer Faruk , Yilmaz, Bilal . "Determination of Chemical Constituents and Bioactive Properties of Alcohol Extracts of Pleurotus sajor-caju and Pleurotus ostreatus". Journal of the Institute of Science and Technology 11 / 3 (Eylül 2021): 1734-1741 . https://doi.org/10.21597/jist.828653
AMA Gülmez Ö. , Özdal M. , Algur Ö. F. , Yilmaz B. Determination of Chemical Constituents and Bioactive Properties of Alcohol Extracts of Pleurotus sajor-caju and Pleurotus ostreatus. Iğdır Üniv. Fen Bil Enst. Der.. 2021; 11(3): 1734-1741.
Vancouver Gülmez Ö. , Özdal M. , Algur Ö. F. , Yilmaz B. Determination of Chemical Constituents and Bioactive Properties of Alcohol Extracts of Pleurotus sajor-caju and Pleurotus ostreatus. Journal of the Institute of Science and Technology. 2021; 11(3): 1734-1741.
IEEE Ö. Gülmez , M. Özdal , Ö. F. Algur ve B. Yilmaz , "Determination of Chemical Constituents and Bioactive Properties of Alcohol Extracts of Pleurotus sajor-caju and Pleurotus ostreatus", Journal of the Institute of Science and Technology, c. 11, sayı. 3, ss. 1734-1741, Eyl. 2021, doi:10.21597/jist.828653