Olgu Sunumu

Treatment of Mucormycosis with Liposomal Amphotericin B, Posaconazole and Deferasirox: A Case Report

Cilt: 6 Sayı: 1 1 Mart 2016
  • Uğur Önal
PDF İndir
EN

Treatment of Mucormycosis with Liposomal Amphotericin B, Posaconazole and Deferasirox: A Case Report

Abstract

In this paper, we present a 69 years old diabetic patient with mucormycosis who was succesfully treated with liposomal amphotericin B (LAMB), posaconazole and deferasirox despite having no adequate surgery. There was no relapse on 6 month post-treatment follow-up. We conclude that combination of antifungal antibiotics with deferasirox may be successful in the salvage therapy of mucormycosis especially in diabetic patients. J Microbiol Infect Dis 2016;6(1): 32-35

Keywords

Kaynakça

  1. 1. Zeka AN, Taşbakan M, Pullukçu H, et al. Evaluation of zygomycosis cases by pooled analysis method reported from Turkey. Mikrobiyol Bul 2013;47:708-716.
  2. 2. Roden MM, Zaoutis TE, Buchanan WL, et al. Epidemiology and outcome of zygomycosis: a review of 929 reported cases. Clin Infect Dis 2005; 41:634-653.
  3. 3. Aslan M, Öz Y, Akay MO, Akşit F. Evaluation of febrile neutropenia in hematologic malignancy patients. Mediterr J Infect Microb Antimicrob 2014; 3:20.
  4. 4. Özden M, Denk A, Demirdağ K, Elkıran T. Investigation of Febrile Neutropenic Cases and Risk Factors. Mediterr J Infect Microb Antimicrob 2014;2:3.
  5. 5. Cornely OA, Arikan-Akdagli S, Dannaoui E, et al. ESCMID and ECMM Joint Clinical Guidelines for the Diagnosis and Management of Mucormycosis 2013. Clin Microbiol Infec 2014; 20 Suppl. 3:5-26.
  6. 6. Ibrahim AS, Gebermariam T, Fu Y, et al. The iron chelator deferasirox protects mice from mucormycosis through iron starvation. J Clin Invest 2007;117: 2649-2657.
  7. 7. Spellberg B, Ibrahim AS, Chin-Hong PV, et al. The Deferasirox–AmBisome Therapy for Mucormycosis (DEFEAT Mucor) study: a randomized, double-blinded, placebo-controlled trial. J Antimicrob Chemother 2012;67:715-722.
  8. 8. Frater JL, Hall GS, Procop GW. Histologic features of zygomycosis: emphasis on perineural invasion and fungal morphology. Arch Pathol Lab Med 2001; 125: 375-378.

Ayrıntılar

Birincil Dil

Türkçe

Konular

Sağlık Kurumları Yönetimi

Bölüm

Olgu Sunumu

Yazarlar

Uğur Önal Bu kişi benim

Yayımlanma Tarihi

1 Mart 2016

Gönderilme Tarihi

16 Temmuz 2017

Kabul Tarihi

6 Ağustos 2015

Yayımlandığı Sayı

Yıl 2016 Cilt: 6 Sayı: 1

Kaynak Göster

APA
Önal, U. (2016). Treatment of Mucormycosis with Liposomal Amphotericin B, Posaconazole and Deferasirox: A Case Report. Journal of Microbiology and Infectious Diseases, 6(1), 32-35. https://doi.org/10.5799/jmid.328767
AMA
1.Önal U. Treatment of Mucormycosis with Liposomal Amphotericin B, Posaconazole and Deferasirox: A Case Report. Journal of Microbiology and Infectious Diseases. 2016;6(1):32-35. doi:10.5799/jmid.328767
Chicago
Önal, Uğur. 2016. “Treatment of Mucormycosis with Liposomal Amphotericin B, Posaconazole and Deferasirox: A Case Report”. Journal of Microbiology and Infectious Diseases 6 (1): 32-35. https://doi.org/10.5799/jmid.328767.
EndNote
Önal U (01 Mart 2016) Treatment of Mucormycosis with Liposomal Amphotericin B, Posaconazole and Deferasirox: A Case Report. Journal of Microbiology and Infectious Diseases 6 1 32–35.
IEEE
[1]U. Önal, “Treatment of Mucormycosis with Liposomal Amphotericin B, Posaconazole and Deferasirox: A Case Report”, Journal of Microbiology and Infectious Diseases, c. 6, sy 1, ss. 32–35, Mar. 2016, doi: 10.5799/jmid.328767.
ISNAD
Önal, Uğur. “Treatment of Mucormycosis with Liposomal Amphotericin B, Posaconazole and Deferasirox: A Case Report”. Journal of Microbiology and Infectious Diseases 6/1 (01 Mart 2016): 32-35. https://doi.org/10.5799/jmid.328767.
JAMA
1.Önal U. Treatment of Mucormycosis with Liposomal Amphotericin B, Posaconazole and Deferasirox: A Case Report. Journal of Microbiology and Infectious Diseases. 2016;6:32–35.
MLA
Önal, Uğur. “Treatment of Mucormycosis with Liposomal Amphotericin B, Posaconazole and Deferasirox: A Case Report”. Journal of Microbiology and Infectious Diseases, c. 6, sy 1, Mart 2016, ss. 32-35, doi:10.5799/jmid.328767.
Vancouver
1.Uğur Önal. Treatment of Mucormycosis with Liposomal Amphotericin B, Posaconazole and Deferasirox: A Case Report. Journal of Microbiology and Infectious Diseases. 01 Mart 2016;6(1):32-5. doi:10.5799/jmid.328767