Patterns of Antimicrobial Resistance in a Pediatric Cardiac Intensive Care Unit: Five Years’ Experience

Yıl 2017, Cilt: 07 Sayı: 03, 132 - 138, 15.09.2017

Nelya Bissenova Aigerim Yergaliyeva

https://doi.org/10.5799/jmid.367532

Cited By: 1

Öz

Objectives: The identification of antimicrobial resistance of
isolates present in pediatric cardiac intensive care unit (PCICU) is important
to prevent further spread, because this department limited choice of
antibiotic. The aim of the present study is to report the antibiotic resistance
rate of most frequently pathogens in PCICU during a five-year period.

Methods:
A prospective study was performed on 4228 clinical samples (bloodstream, wound
samples, respiratory tract, tracheobronchial tree, and central venous catheter)
from patients in PCICU during the period 2012-2016. Identification of isolates
and antibiotic susceptibility testing were performed by Vitek 2 automated
system.

Results:
The percentages of most frequently isolated microorganisms in our PCICU were as
follows: Klebsiella pneumoniae 8.9%, Pseudomonas aeruginosa 7.5%, Staphylococcus
aureus 6.9%, Coagulase-Negative Staphylococci
5.3%, and Candida spp. 3.4%.
During study period there is tendency increasing the percentage of detection P. aeruginosa from 2.6% to 10.8%
(p=0.018), K. pneumoniae from 2.6% to
10.5% (p=0.023), and Candida spp. from 1.6% to 5.9% (p=0.033). These
isolates showed tendency of significant increasing resistance to 3rd generation
cephalosporins and carbapenems.

Conclusion: The present study
reported that most frequent isolates in our PCICU were P. aeruginosa and K. pneumoniae. Reporting of dramatically
increasing resistance rates of these isolates necessitates a well-designed
hospital infection control strategy, including good hygiene, microbiological
monitoring; all of this will greatly reduce the risk of nosocomial infection.

Anahtar Kelimeler

microbiologic monitoring, antibiotic resistance, pediatric cardiac intensive care unit

Kaynakça

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