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Seroprevalence of Cytomegaloviruses in Afghanistan

Yıl 2019, Cilt: 09 Sayı: 02, 78 - 82, 15.06.2019
https://doi.org/10.5799/jmid.574566

Öz

ABSTRACT



Objective: Human Cytomegalovirus (CMV) is a member of the Herpesviridae
family, with the ability to establish a long-lived latent infection. CMV infection
causes problems in immunocompromised hosts undergoing organ and stem cell
transplantation. The prevalence of CMV in adults varies in different geographic
regions. The purpose of this study was to assess the prevalence of CMV in the
adult population of Afghanistan, which did not have epidemiologic information
for CMV infection.



Methods: A
total of 500 adults residing in main regional provinces of Afghanistan
including Nangarhar, Herat, Mazar-i Sharif, Kandahar and Kabul in the age range
of 25-70 years old were randomly selected to include in the study. Among the
participants, 263 (52.6%) were female and 237 (47.4%) were male. The samples
were tested for the presence of CMV IgM and IgG antibodies using
chemiluminescence immunoassay on the Abbott Architect automated platform.



Results:
The
seropositivity of CMV was found 99.79 % in Afghanistan. There were no significant
differences in the prevalence CMV infection among the five regions. The
seropositivity anti-CMV IgG positive rate in Kandahar, Kabul, Nangarhar and,
Herat was determined as 100%.  The CMV
IgG prevalence was 98.99% in Mazar-i Sharif. Anti CMV IgM was found 1.24% in
Afghanistan.



Conclusions: Our study shown that
the seroprevalence is high in Afghanistan. Because of the high frequency of
seropositivity in general population in Afghanistan, the approaches for
preventing CMV reactivation need to be developed.  J
Microbiol Infect Dis 2019; 9(2): 78-82.

Kaynakça

  • ABSTRACT Objective: Human Cytomegalovirus (CMV) is a member of the Herpesviridae family, with the ability to establish a long-lived latent infection. CMV infection causes problems in immunocompromised hosts undergoing organ and stem cell transplantation. The prevalence of CMV in adults varies in different geographic regions. The purpose of this study was to assess the prevalence of CMV in the adult population of Afghanistan, which did not have epidemiologic information for CMV infection. Methods: A total of 500 adults residing in main regional provinces of Afghanistan including Nangarhar, Herat, Mazar-i Sharif, Kandahar and Kabul in the age range of 25-70 years old were randomly selected to include in the study. Among the participants, 263 (52.6%) were female and 237 (47.4%) were male. The samples were tested for the presence of CMV IgM and IgG antibodies using chemiluminescence immunoassay on the Abbott Architect automated platform. Results: The seropositivity of CMV was found 99.79 % in Afghanistan. There were no significant differences in the prevalence CMV infection among the five regions. The seropositivity anti-CMV IgG positive rate in Kandahar, Kabul, Nangarhar and, Herat was determined as 100%. The CMV IgG prevalence was 98.99% in Mazar-i Sharif. Anti CMV IgM was found 1.24% in Afghanistan. Conclusions: Our study shown that the seroprevalence is high in Afghanistan. Because of the high frequency of seropositivity in general population in Afghanistan, the approaches for preventing CMV reactivation need to be developed. J Microbiol Infect Dis 2019; 9(2): 78-82.
Yıl 2019, Cilt: 09 Sayı: 02, 78 - 82, 15.06.2019
https://doi.org/10.5799/jmid.574566

Öz

Kaynakça

  • ABSTRACT Objective: Human Cytomegalovirus (CMV) is a member of the Herpesviridae family, with the ability to establish a long-lived latent infection. CMV infection causes problems in immunocompromised hosts undergoing organ and stem cell transplantation. The prevalence of CMV in adults varies in different geographic regions. The purpose of this study was to assess the prevalence of CMV in the adult population of Afghanistan, which did not have epidemiologic information for CMV infection. Methods: A total of 500 adults residing in main regional provinces of Afghanistan including Nangarhar, Herat, Mazar-i Sharif, Kandahar and Kabul in the age range of 25-70 years old were randomly selected to include in the study. Among the participants, 263 (52.6%) were female and 237 (47.4%) were male. The samples were tested for the presence of CMV IgM and IgG antibodies using chemiluminescence immunoassay on the Abbott Architect automated platform. Results: The seropositivity of CMV was found 99.79 % in Afghanistan. There were no significant differences in the prevalence CMV infection among the five regions. The seropositivity anti-CMV IgG positive rate in Kandahar, Kabul, Nangarhar and, Herat was determined as 100%. The CMV IgG prevalence was 98.99% in Mazar-i Sharif. Anti CMV IgM was found 1.24% in Afghanistan. Conclusions: Our study shown that the seroprevalence is high in Afghanistan. Because of the high frequency of seropositivity in general population in Afghanistan, the approaches for preventing CMV reactivation need to be developed. J Microbiol Infect Dis 2019; 9(2): 78-82.
Toplam 1 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Bölüm Research Article
Yazarlar

Abbas Ali Husseini

İsil Fidan Bu kişi benim

Khwaja Mir İslam Saeed Bu kişi benim

A. Mithat Bozdayı Bu kişi benim

Yayımlanma Tarihi 15 Haziran 2019
Yayımlandığı Sayı Yıl 2019 Cilt: 09 Sayı: 02

Kaynak Göster

APA Husseini, A. A., Fidan, İ., Saeed, K. M. İ., Bozdayı, A. M. (2019). Seroprevalence of Cytomegaloviruses in Afghanistan. Journal of Microbiology and Infectious Diseases, 09(02), 78-82. https://doi.org/10.5799/jmid.574566
AMA Husseini AA, Fidan İ, Saeed KMİ, Bozdayı AM. Seroprevalence of Cytomegaloviruses in Afghanistan. J Microbil Infect Dis. Haziran 2019;09(02):78-82. doi:10.5799/jmid.574566
Chicago Husseini, Abbas Ali, İsil Fidan, Khwaja Mir İslam Saeed, ve A. Mithat Bozdayı. “Seroprevalence of Cytomegaloviruses in Afghanistan”. Journal of Microbiology and Infectious Diseases 09, sy. 02 (Haziran 2019): 78-82. https://doi.org/10.5799/jmid.574566.
EndNote Husseini AA, Fidan İ, Saeed KMİ, Bozdayı AM (01 Haziran 2019) Seroprevalence of Cytomegaloviruses in Afghanistan. Journal of Microbiology and Infectious Diseases 09 02 78–82.
IEEE A. A. Husseini, İ. Fidan, K. M. İ. Saeed, ve A. M. Bozdayı, “Seroprevalence of Cytomegaloviruses in Afghanistan”, J Microbil Infect Dis, c. 09, sy. 02, ss. 78–82, 2019, doi: 10.5799/jmid.574566.
ISNAD Husseini, Abbas Ali vd. “Seroprevalence of Cytomegaloviruses in Afghanistan”. Journal of Microbiology and Infectious Diseases 09/02 (Haziran 2019), 78-82. https://doi.org/10.5799/jmid.574566.
JAMA Husseini AA, Fidan İ, Saeed KMİ, Bozdayı AM. Seroprevalence of Cytomegaloviruses in Afghanistan. J Microbil Infect Dis. 2019;09:78–82.
MLA Husseini, Abbas Ali vd. “Seroprevalence of Cytomegaloviruses in Afghanistan”. Journal of Microbiology and Infectious Diseases, c. 09, sy. 02, 2019, ss. 78-82, doi:10.5799/jmid.574566.
Vancouver Husseini AA, Fidan İ, Saeed KMİ, Bozdayı AM. Seroprevalence of Cytomegaloviruses in Afghanistan. J Microbil Infect Dis. 2019;09(02):78-82.