Akupunkturun İnfertilite Tedavisinde Canlı Doğum ve Gebelik Sonuçlarına Etkisi: Sistematik Derleme

Öz

Giriş: İnfertilite tedavisi teknolojinin gelişmesiyle önemli sonuçlar elde etmiş olsa da, başarı sonucunu arttırmak adına infertilite tedavisi ile birlikte kullanılan tamamlayıcı/alternatif tedavilere yönelim artmaktadır. Amaç: Bu sistematik derlemede infertilite tedavisinde akupunktur uygulamasının, gebelik ve canlı doğum sonuçları üzerine etkisini inceleyen araştırma sonuçlarını sistematik olarak değerlendirmek amaçlanmıştır. Yöntem: Bu sistematik derleme başlangıç yıl sınırı yapılmadan Ağustos 2023- Ekim 2023 tarihleri arasında Cochrane, Science Direct ve Pubmed veri tabanları tarandı. Yayınlanan 847 çalışmadan 15 çalışma inceleme kapsamına alındı. Bulgular: Sistematik derlemeye dahil edilen 15 çalışmadan; 6 çalışmada akupunkturun canlı doğum sonucunu olumlu etkilediği 8 çalışmada ise etkilemediği belirlenmiştir. 1 çalışmada örneklem grubundaki kadınların canlı gebelik oranı etkilenmese de 35 yaş üstü kadınlarda akupunkturun etkili olduğu sonucu elde edilmiştir. Çalışmalarda akupunkturun farklı zamanlarda, farklı bölgelere uygulanması, kontrol gruplarında hiç akupunktur uygulanmayan veya plasebo akupunktur uygulanan (sahte iğne ile gerçek akupunktur grubu ile aynı bölgeye uygulananlar veya akupunktur bölgesi olmayan yerlere uygulananlar) grupların oluşturulması gibi heterojeniteler bulunmaktadır. Sonuç: 15 çalışmanın incelendiği sistematik derlemede; akupunkturun gebelik ve canlı doğum oranlarını arttırdığını belirten ve etkilemediği sonucuna ulaşan çalışma sayıları birbirine çok yakındır. Akupunktur uygulanmasının infertilite tedavisinde yer alması, tartışmalı bir konu olarak devamlılığını korumakta ve konu ile ilgili kanıt düzeyi yüksek randomize kontrollü çalışmalara ihtiyaç duyulmaktadır.

Anahtar Kelimeler

• akupunktur
• canlı doğum
• infertilite

The Effect Of Acupuncture On Live Birth And Preganancy Outcomes In Infertility Treatment: Systematic Review

Öz

Background: Although infertility treatment has achieved significant results with the development of technology, the tendency towards complementary/alternative treatments used together with infertility treatment is on the rise in order to increase the success result. Objectives: In this systematic review, it is aimed to systematically evaluate the results of research examining the effect of acupuncture application in infertility treatment on pregnancy and live birth outcomes. Methods: Cochrane, Science Direct and Pubmed databases were scanned between August 2023 and October 2023, without setting a starting year limit for this systematic review.Of the 847 published studies, 15 studies were included in the scope of the review. Results: Out of the 15 studies included in the systematic review; It was determined that acupuncture had a positive effect on live birth outcomes in 6 studies and did not have any effect on live birth outcomes in 8 studies.In one study, it was concluded that acupuncture was effective in women over the age of 35, although the live pregnancy rate of the women in the sample group was not affected.There are heterogeneities in studies such as applying acupuncture to different areas at different times, creating control groups that never applied acupuncture or applied placebo acupuncture (those applied to the same area as the real acupuncture group with a fake needle or those applied to places without an acupuncture zone). Conclusion: In the systematic review that examined 15 studies; the number of studies stating that acupuncture increases pregnancy and live birth rates and those concluding that it does not affect pregnancy and live birth rates are very close to each other. The inclusion of acupuncture in infertility treatment remains a controversial issue and randomized controlled trials with high levels of evidence are needed on this subject.

Anahtar Kelimeler

• acupuncture
• live birth
• infertility

Kaynakça

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