Olgu Sunumu
BibTex RIS Kaynak Göster

ANTİFOSFOLİPİT ANTİKOR SENDROMLU HASTADA TRİKÜSPİT KAPAKTA PAPİLLER FİBROELASTOM VE NONBAKTERİYEL TROMBOTİK ENDOKARDİT BİRLİKTELİĞİ OLGU SUNUMU

Yıl 2025, Cilt: 7 Sayı: 2, 45 - 48, 02.01.2026

Öz

Primer kardiyak tümörler nadir görülmekte olup, genellikle benign karakterlidir. Bu tümörler arasında en sık rastlananlardan biri papiller fibroelastomdur . Papiller fibroelastom genellikle asemptomatik seyretse de, ciddi embolik komplikasyonlara yol açabilir. Bu olgu sunumunda, 42 yaşında erkek antifosfolipid antikor sendromu tanısı bulunan ve triküspit kapakta papiller fibroelastom zemininde gelişen nonbakteriyel trombotik endokardit vakası sunulmuştur Patolojik inceleme, papiller fibroelastom ve nonbakteriyel trombotik endokardit lehine değerlendirilmiştir. Olgu, papiller fibroelastom ve nonbakteriyel trombotik endokardit birlikteliğinin antifosfolipid antikor sendromu ile ilişkili olabileceğini göstermesi açısından dikkat çekicidir. Ayrıca, romatolojik hastalıkların kardiyak tutulumu ve kapak patolojilerinin embolik riskleri açısından dikkatli olunması gerektiği vurgulanmaktadır.

Kaynakça

  • Devanabanda AR, Lee LS. Papillary Fibroelastoma. 2023 Apr 26. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–. PMID: 31751019.
  • Gaetano Thiene, Cristina Basso. Pathology and pathogenesis of infective endocarditis in native heart valves, Cardiovascular Pathology, 2006:15(5);256-263.
  • Gowda RM, Khan IA, Nair CK, Mehta NJ, Vasavada BC, Sacchi TJ. Cardiac papillary fibroelastoma: a comprehensive analysis of 725 cases. Am Heart J. 2003 Sep;146(3):404-10. doi: 10.1016/S0002-8703(03)00249-7. PMID: 12947356.
  • Işık M, Fındık S, Tatar S, Kara Ş, Görmüş N. Could papillary fibroelastoma in the tricuspid valve cause trombocytopenia? Turk Gogus Kalp Damar Cerrahisi Derg. 2024 Sep 20;33(1):117-120. doi: 10.5606/tgkdc. dergisi.2024.25719.
  • Ramesh M Gowda, Ijaz A Khan, Chandra K Nair, Nirav J Mehta, Balendu C Vasavada, Terrence J Sacchi,Cardiac papillary fibroelastoma: a comprehensive analysis of 725 cases, American Heart Journal, Volume 146, Issue 3, 2003, Pages 404-410, ISSN 0002-8703,
  • Reda Bzikha, Amin Serradj, Sébastien Queron,Papillary fibroelastoma of aortic valve mimicking an infective endocarditis,Cirugía Cardiovascular,Volume 28, Issue 5,2021,Pages 300-303
  • Şimşek-Yavuz S, Akar AR, Aydoğdu S, et al. [Diagnosis, treatment and prevention of infective endocarditis: Turkish consensus report]. Klimik Derg. 2019; 32 (Suppl. 1): 2-116. Turkish.
  • Zmaili MA, Alzubi JM, Kocyigit D, Bansal A, Samra GS, Grimm R, Griffin BP, Xu B. A Contemporary 20-Year Cleveland Clinic Experience of Nonbacterial Trombotic Endocarditis: Etiology, Echocardiographic Imaging, Management, and Outcomes. Am J Med. 2021 Mar;134(3):361-369.
  • Zoltowska DM, Sadic E, Becoats K, Ghetiya S, Ali AA, Sattiraju S, Missov E. Cardiac papillary fibroelastoma. J Geriatr Cardiol. 2021 May 28;18(5):346-351. doi: 10.11909/j.issn.1671-5411.2021.05.009.

Case Report: Concomitant Papillary Fibroelastoma and Non-Bacterial Thrombotic Endocarditis of the Tricuspid Valve in a Patient with Antiphospholipid Antibody Syndrome

Yıl 2025, Cilt: 7 Sayı: 2, 45 - 48, 02.01.2026

Öz

Primary cardiac tumors are rare and usually benign. Among these, papillary fibroelastoma is one of the most frequently encountered types. Although often asymptomatic, papillary fibroelastoma can lead some serious embolic complications. This case report presents a 42-year-old male patient diagnosed with antiphospholipid antibody syndrome, who developed nonbacterial thrombotic endocarditis on a tricuspid valve papillary fibroelastoma. Histopathological findings supported a diagnosis of papillary fibroelastoma with coexisting nonbacterial thrombotic endocarditis, This case highlights the association between papillary fibroelastoma and nonbacterial thrombotic endocarditis in the context of antiphospholipid antibody syndrome, emphasizing the importance of clinical vigilance regarding cardiac involvement in rheumatologic diseases and the embolic potential of valvular masses.

Kaynakça

  • Devanabanda AR, Lee LS. Papillary Fibroelastoma. 2023 Apr 26. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–. PMID: 31751019.
  • Gaetano Thiene, Cristina Basso. Pathology and pathogenesis of infective endocarditis in native heart valves, Cardiovascular Pathology, 2006:15(5);256-263.
  • Gowda RM, Khan IA, Nair CK, Mehta NJ, Vasavada BC, Sacchi TJ. Cardiac papillary fibroelastoma: a comprehensive analysis of 725 cases. Am Heart J. 2003 Sep;146(3):404-10. doi: 10.1016/S0002-8703(03)00249-7. PMID: 12947356.
  • Işık M, Fındık S, Tatar S, Kara Ş, Görmüş N. Could papillary fibroelastoma in the tricuspid valve cause trombocytopenia? Turk Gogus Kalp Damar Cerrahisi Derg. 2024 Sep 20;33(1):117-120. doi: 10.5606/tgkdc. dergisi.2024.25719.
  • Ramesh M Gowda, Ijaz A Khan, Chandra K Nair, Nirav J Mehta, Balendu C Vasavada, Terrence J Sacchi,Cardiac papillary fibroelastoma: a comprehensive analysis of 725 cases, American Heart Journal, Volume 146, Issue 3, 2003, Pages 404-410, ISSN 0002-8703,
  • Reda Bzikha, Amin Serradj, Sébastien Queron,Papillary fibroelastoma of aortic valve mimicking an infective endocarditis,Cirugía Cardiovascular,Volume 28, Issue 5,2021,Pages 300-303
  • Şimşek-Yavuz S, Akar AR, Aydoğdu S, et al. [Diagnosis, treatment and prevention of infective endocarditis: Turkish consensus report]. Klimik Derg. 2019; 32 (Suppl. 1): 2-116. Turkish.
  • Zmaili MA, Alzubi JM, Kocyigit D, Bansal A, Samra GS, Grimm R, Griffin BP, Xu B. A Contemporary 20-Year Cleveland Clinic Experience of Nonbacterial Trombotic Endocarditis: Etiology, Echocardiographic Imaging, Management, and Outcomes. Am J Med. 2021 Mar;134(3):361-369.
  • Zoltowska DM, Sadic E, Becoats K, Ghetiya S, Ali AA, Sattiraju S, Missov E. Cardiac papillary fibroelastoma. J Geriatr Cardiol. 2021 May 28;18(5):346-351. doi: 10.11909/j.issn.1671-5411.2021.05.009.
Toplam 9 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Kardiyovasküler Tıp ve Hematoloji (Diğer)
Bölüm Olgu Sunumu
Yazarlar

Mehmet Işık 0000-0002-2154-7473

Fatmanur Tutsoy 0000-0002-1331-5074

Serkan Yıldırım 0000-0003-1424-8628

Yalçın Günerhan 0000-0003-3104-7920

Niyazi Görmüş 0000-0002-8264-3653

Gönderilme Tarihi 12 Ağustos 2025
Kabul Tarihi 20 Kasım 2025
Yayımlanma Tarihi 2 Ocak 2026
Yayımlandığı Sayı Yıl 2025 Cilt: 7 Sayı: 2

Kaynak Göster

APA Işık, M., Tutsoy, F., Yıldırım, S., … Günerhan, Y. (2026). Case Report: Concomitant Papillary Fibroelastoma and Non-Bacterial Thrombotic Endocarditis of the Tricuspid Valve in a Patient with Antiphospholipid Antibody Syndrome. Doğal Yaşam Tıbbı Dergisi, 7(2), 45-48. https://doi.org/10.71051/jnlm.1762372
AMA Işık M, Tutsoy F, Yıldırım S, Günerhan Y, Görmüş N. Case Report: Concomitant Papillary Fibroelastoma and Non-Bacterial Thrombotic Endocarditis of the Tricuspid Valve in a Patient with Antiphospholipid Antibody Syndrome. DYT. Ocak 2026;7(2):45-48. doi:10.71051/jnlm.1762372
Chicago Işık, Mehmet, Fatmanur Tutsoy, Serkan Yıldırım, Yalçın Günerhan, ve Niyazi Görmüş. “Case Report: Concomitant Papillary Fibroelastoma and Non-Bacterial Thrombotic Endocarditis of the Tricuspid Valve in a Patient with Antiphospholipid Antibody Syndrome”. Doğal Yaşam Tıbbı Dergisi 7, sy. 2 (Ocak 2026): 45-48. https://doi.org/10.71051/jnlm.1762372.
EndNote Işık M, Tutsoy F, Yıldırım S, Günerhan Y, Görmüş N (01 Ocak 2026) Case Report: Concomitant Papillary Fibroelastoma and Non-Bacterial Thrombotic Endocarditis of the Tricuspid Valve in a Patient with Antiphospholipid Antibody Syndrome. Doğal Yaşam Tıbbı Dergisi 7 2 45–48.
IEEE M. Işık, F. Tutsoy, S. Yıldırım, Y. Günerhan, ve N. Görmüş, “Case Report: Concomitant Papillary Fibroelastoma and Non-Bacterial Thrombotic Endocarditis of the Tricuspid Valve in a Patient with Antiphospholipid Antibody Syndrome”, DYT, c. 7, sy. 2, ss. 45–48, 2026, doi: 10.71051/jnlm.1762372.
ISNAD Işık, Mehmet vd. “Case Report: Concomitant Papillary Fibroelastoma and Non-Bacterial Thrombotic Endocarditis of the Tricuspid Valve in a Patient with Antiphospholipid Antibody Syndrome”. Doğal Yaşam Tıbbı Dergisi 7/2 (Ocak2026), 45-48. https://doi.org/10.71051/jnlm.1762372.
JAMA Işık M, Tutsoy F, Yıldırım S, Günerhan Y, Görmüş N. Case Report: Concomitant Papillary Fibroelastoma and Non-Bacterial Thrombotic Endocarditis of the Tricuspid Valve in a Patient with Antiphospholipid Antibody Syndrome. DYT. 2026;7:45–48.
MLA Işık, Mehmet vd. “Case Report: Concomitant Papillary Fibroelastoma and Non-Bacterial Thrombotic Endocarditis of the Tricuspid Valve in a Patient with Antiphospholipid Antibody Syndrome”. Doğal Yaşam Tıbbı Dergisi, c. 7, sy. 2, 2026, ss. 45-48, doi:10.71051/jnlm.1762372.
Vancouver Işık M, Tutsoy F, Yıldırım S, Günerhan Y, Görmüş N. Case Report: Concomitant Papillary Fibroelastoma and Non-Bacterial Thrombotic Endocarditis of the Tricuspid Valve in a Patient with Antiphospholipid Antibody Syndrome. DYT. 2026;7(2):45-8.