Incidence of Infiltration and Phlebitis and Risk Factors Among Chemotherapy Patients: An Observational Prospective Cohort Study

Yıl 2023, Cilt: 26 Sayı: 1, 18 - 26, 29.03.2023

Şule Bıyık Bayram Emel Gülnar Nevnihal Akbaytürk Nurcan Çalışkan

https://doi.org/10.5152/JANHS.2023.2287143

Cited By: 1

Öz

Objective: This study aimed to identify the incidence rate of infiltration, phlebitis, and risk factors in chemotherapy patients.

Methods: This observational prospective cohort study was conducted in the oncology and hematology clinics of a hospital in Turkey. Peripheral intravenous catheter insertion sites (n = 175) on
99 patients were monitored. Researchers monitored the peripheral intravenous catheter insertion sites for 5 days after nurses inserted them. The ethics committee approved the study.

Results: The incidence of infiltration and phlebitis was, respectively, 9.7% and 17.5%. The incidence rate of infiltration was significantly higher, respectively, in the case of vesicants and the presence
of neutropenia among patients over 52 years of age. It was determined that the risk of infiltration in women was 0.21 times higher than in men. When the neutropenia value was put into the
model alone, it was determined that the risk of infiltration increased 0.414 times in the case of neutropenia.

Conclusion: The patient’s gender, the presence of neutropenia, and the chemotherapy drug type affect the incidence of infiltration. Regular follow-up of the catheter site will reduce the workload
of the nurse by ensuring the continuation of patient care and treatment without interruption. It will also reduce the frequency of the catheterization procedure and prevent the difficulties it
brings to the patient.

Anahtar Kelimeler

Catheterization, drug therapy, nursing, phlebitis

Kemoterapi Alan Hastalarda İnfiltrasyon ve Flebit Görülme Sıklığı ve Risk Faktörleri: Gözlemsel Prospektif Çalışma

Öz

Amaç: Bu çalışma, kemoterapi alan hastalarda infiltrasyon ve flebit görülme sıklığı ve risk faktörlerini belirlemek amacıyla yapılmıştır.

Yöntemler: Bu çalışma Türkiye’de bir Üniversite Hastanesinin Onkoloji ve Hematoloji Kliniklerinde gözlemsel prospektif olarak yapılmıştır. Çalışmada, periferik intravenöz kateter uygulaması yapılan 99 hastanın 175 kateter bölgesi takip edilmiştir. Çalışma kriterlerine uyan hastaların hastanede kaldıkları süre içinde tekrarlı takılan kateter bölgeleri 5 gün takip edilmiştir. Çalışmanın yapılabilmesi için etik kuruldan ve kurumdan yazılı izin alınmıştır.

Bulgular: Çalışma sonucunda periferik intravenöz kateter uygulamasının %9,7’sinde infiltrasyon, %17,7’sinde flebit görülmüştür. 52 yaş üstü, nötropenik ve vezikan ilaç kullanımının infiltrasyon riskini arttırdığı belirlenmiştir. Kadınlarda infiltrasyon riskinin erkeklere göre 0,21 kat daha fazla olduğu belirlenmiştir. Nötropeni tek başına modele alındığında nötropeni durumunda infiltrasyon riskinin 0,414 kat arttığı belirlenmiştir.

Sonuç: Çalışma sonucunda, hastanın cinsiyeti, nötropeni ve ilaç türünün infiltrasyon durumunu etkilediği belirlenmiştir. Kateter bölgesinin düzenli takip edilmesi hasta bakımının ve tedavisinin aksamadan devamını sağlayacaktır. Ayrıca kateterizasyon işleminin sıklığını azaltacak ve hastaya getirdiği zorlukları önleyecektir.

Anahtar Kelimeler

Flebit, hemşire, ilaç uygulaması, kateterizasyon

Kaynakça

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