Araştırma Makalesi
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Tip 1 Diyabetli Adölesanlarda Hipoglisemi Korkusunun Glisemik Kontrol ve Yaşam Kalitesi Üzerine Etkisi

Yıl 2025, Cilt: 28 Sayı: 3, 233 - 239, 24.09.2025
https://doi.org/10.17049/jnursology.1555373

Öz

Amaç: Bu çalışmanın amacı tip 1 diyabetli adölesanlarda hipoglisemi korkusunun glisemik kontrol ve yaşam kalitesi üzerine etkisini belirlemektir.

Yöntemler: Bu araştırma, tanımlayıcı bir çalışma olarak gerçekleştirilmiştir. Araştırma, 13-18 yaş arası Tip 1 diabetes mellitus tanılı 117 adölesan ile yapılmıştır. Veriler, Temmuz 2023 ile Şubat 2024 tarihleri arasında toplanmıştır. Veriler kişisel bilgi formu, Virginia Çocuk/Ergen Düşük Kan Şekeri Ölçeği ve Çocuklar için Yaşam Kalitesi Ölçeği kullanılarak yüz yüze toplanmıştır. Ölçeklerden elde edilen verilerin analizinde Pearson korelasyon analizi ve basit doğrusal regresyon analizi kullanılmıştır.

Bulgular: Bu çalışmada ergenlerin hipoglisemi korku puan ortalaması düşük (45,15±7,13) ve benzer şekilde yaşam kalitesi puan ortalaması düşük (25,48±14,09) bulundu. Hipoglisemi korkusu ile HbA1c düzeyi arasında anlamlı bir korelasyon saptanmadı (r = 0,099, P = ,288). Hipoglisemi korkusu ile yaşam kalitesi arasında negatif bir korelasyon bulundu (r = -0,184; P < ,05).

Sonuç: Hipoglisemi korkusu ile glisemik kontrol arasında ilişki bulunmazken, hipoglisemi korkusu yüksek olan adölesanların yaşam kalitesinde azalma olduğu saptanmıştır. Hemşireler hipogliseminin fizyolojik etkilerini değerlendirirken psikolojik etkilerini de değerlendirmeli, adölesanların diyabetle ilgili korkularını ifade etmelerine izin vermeli ve multidisipliner bir yaklaşımla sorunlarına çözüm bulmalıdır.

Kaynakça

  • 1. Patterson CC, Karuranga S, Salpea P, et al. Worldwide estimates of incidence, prevalence and mortality of type 1 diabetes in children and adolescents: Results from the International Diabetes Federation Diabetes Atlas, 9th edition. Diabetes Res Clin Pract. 2019;157:107842. https://doi.org/10.1016/j.diabres.2019.107842.
  • 2. American Diabetes Association. 2. Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes-2021. Diabetes Care. 2021;44(Supplement_1):15-33. https://doi.org/10.2337/dc21-S002.
  • 3. Diouri O, Cigler M, Vettoretti M, et al. Hypoglycemia detection and prediction techniques: A systematic review on the latest developments. Diabetes Metab Res Rev. 2021;37(7). https://doi.org/10.1002/dmrr.3449.
  • 4. Abitbol L, Palmert MR. When low blood sugars cause high anxiety: Fear of hypoglycemia among parents of youth with type 1 diabetes mellitus. Can J Diabetes. 2021;45(5):403-410. https://doi.org/10.1016/j.jcjd.2020.08.098.
  • 5. Zhang L, Xu H, Liu L, et al. Related factors associated with fear of hypoglycemia in parents of children and adolescents with type 1 diabetes-A systematic review. J Pediatr Nurs. 2022;66:125-135. https://doi.org/10.1016/j.pedn.2022.05.022.
  • 6. Desjardins K, Brazeau AS, Strychar I, Rabasa-Lhoret R. Are bedtime nutritional strategies effective in preventing nocturnal hypoglycemia in patients with type 1 diabetes? Diabetes Obes Metab. 2014;16(7):577-587. https://doi.org/10.1111/dom.12232.
  • 7. Brazeau AS, Rabasa-Lhoret R, Strychar I, Mircescu H. Barriers to physical activity among patients with type 1 diabetes. Diabetes Care. 2008;31(11):2108-2109. https://doi.org/10.2337/dc08-0720.
  • 8. Przezak A, Bielka W, Molęda P. Fear of hypoglycemia-An underestimated problem. Brain Behav. 2022;12(7):e2633. https://doi.org/10.1002/brb3.2633.
  • 9. Ata SM, Uysal G. Determination of the relationship between fear of hypoglycemia and quality of life in adolescents with diabetes. JAREN. 2022;8(3):131-139. https://doi.org/10.55646/jaren.2022.24650.
  • 10. Brzuszek M, Kochman M, Mazur A. Psychodiabetology: The challenge of the future? J Clin Med. 2024;13(8):2236. https://doi.org/10.3390/jcm13082236.
  • 11. Cooke D, Bond R, Lawton J, et al. Structured type 1 diabetes education delivered within routine care: Impact on glycemic control and diabetes-specific quality of life. Diabetes Care. 2013;36(2):270-272. https://doi.org/10.2337/dc12-0080.
  • 12. Demir G, Akcay N. Diabetes education in children with type 1 diabetes and their families. Turk J Fam Med Prim Care. 2022;16(2):447-455. https://doi.org/10.21763/tjfmpc.936444.
  • 13. Alpar R. Applied statistics and validity and reliability with examples from health and education sciences. Istanbul: Detay; 2010.
  • 14. Gonder-Frederick LA, Fishera CD, Ritterbanda LM, et al. Predictors of fear of hypoglycemia in adolescents with type 1 diabetes and their parent. Pediatr Diabetes. 2006;7:215-222. https://doi.org/10.1111/j.1399-5448.2006.00182.x.
  • 15. Sahin NŞ, Ozcelik CC. University of Virginia child/adolescent low blood glucose scale: Turkish validity and reliability study. J Educ Res Nurs. 2017;14(3):198-203. https://doi.org/10.5222/HEAD.2017.198.
  • 16. Varni JW, Seid M, Rode CA. The PedsQL™: Measurement model for the pediatric quality of life inventory. Med Care. 1999;126-139. https://doi.org/10.1097/00005650-199902000-00003
  • 17. Memik NC, Agaoglu B, Coskun A, Uneri OS, Karakaya I. Validity and reliability of the 13-18 years old adolescent form of the quality of life scale for children. Turk J Psychiatry. 2007;18(4):353-363.
  • 18. Mayers A. Introduction to statistics and SPSS in psychology. Pearson; 2013.
  • 19. Khunti K, Alsifri S, Aronson R, et al. Impact of hypoglycemia on patient-reported outcomes from a global, 24-country study of 27,585 people with type 1 and insulin-treated type 2 diabetes. Diabetes Res Clin Pract. 2017;130:121-129. https://doi.org/10.1016/j.diabres.2017.05.004.
  • 20. Strandberg RB, Graue M, Wentzel-Larsen T, et al. The relationships among fear of hypoglycemia, diabetes-related quality of life and psychological well-being in Norwegian adults with type 1 diabetes. Diabetes Res Clin Pract. 2017;124:11-19. https://doi.org/10.1016/j.diabres.2016.12.018.
  • 21. Gül S, Asiret GD, Okatan C. Investigation of hypoglycemia fear of individuals with type 2 diabetes mellitus. Dokuz Eylul Univ Fac Nurs Electron J. 2021;14(3):179-187. https://doi.org/10.46483/deuhfed.825712.
  • 22. Glocker V, Bachmann S, Hess M, Szinnai G, Burckhardt MA. Fear of hypoglycemia and quality of life in young people with type 1 diabetes and their parents in the era of sensor glucose monitoring. Front Endocrinol (Lausanne). 2022;13:958671. https://doi.org/10.3389/fendo.2022.958671.
  • 23. Zeitoun MH, Reheem AAA, Kharboush IF, et al. Relationship between depressive and anxiety symptoms and fear of hypoglycemia among adolescents and adults with type 1 diabetes mellitus. Prim Care Diabetes. 2023;17(3):255-259. https://doi.org/10.1016/j.pcd.2023.03.002.
  • 24. Ng SM, Moore HS, Clemente MF, Pintus D, Soni A. Continuous glucose monitoring in children with type 1 diabetes improves well-being, alleviates worry and fear of hypoglycemia. Diabetes Technol Ther. 2019;21(3):133-137. https://doi.org/10.1089/dia.2018.0347.
  • 25. Souza MA, Freitas RWJF, Lima LS, et al. Health-related quality of life of adolescents with type 1 diabetes mellitus. Rev Lat Am Enfermagem. 2019;27:e3210. https://doi.org/10.1590/1518-8345.2961.3210.
  • 26. Marques RDM, Rodrigues ML, Santos CR, et al. Associated factors with the quality of life of adolescents with type 1 diabetes. Clin Nutr ESPEN. 2021;42:387-392. https://doi.org/10.1016/j.clnesp.2020.12.018.
  • 27. Saulnier PJ, Briet C, Gand E, et al. No association between fear of hypoglycemia and blood glucose variability in type 1 diabetes: The cross-sectional VARDIA study. J Diabetes Complications. 2019;33(8):554-560. https://doi.org/10.1016/j.jdiacomp.2019.05.003.
  • 28. Andreopoulou O, Kostopoulou E, Kotanidou E, et al. Evaluation of the possible impact of the fear of hypoglycemia on diabetes management in children and adolescents with type 1 diabetes mellitus and their parents: A cross-sectional study. Hormones (Athens). 2024;23(3):419-428. https://doi.org/10.1007/s42000-024-00560-z.
  • 29. Johnson SR, Cooper MN, Davis EA, Jones TW. Hypoglycemia, fear of hypoglycemia and quality of life in children with type 1 diabetes and their parents. Diabet Med. 2013;30(9):1126-1131. https://doi.org/10.1111/dme.12247.
  • 30. Shepard JA, Vajda K, Nyer M, Clarke W, Gonder-Frederick L. Understanding the structure of fear of hypoglycemia in paediatric type 1 diabetes. J Pediatr Psychol. 2014;39(10):1115-1125. https://doi.org/10.1093/jpepsy/jsu069.
  • 31. Amiri F, Vafa M, Gonder-Frederick L. Glycemic Control, Self-Efficacy and Fear of Hypoglycemia among Iranian children with type 1 diabetes. Can J Diabetes. 2015;39:302-307. https://doi.org/10.1016/j.jcjd.2014.12.011
  • 32. Chatwin H, Broadley M, Valdersdorf Jensen M, et al. ‘Never again will I be carefree’: a qualitative study of the impact of hypoglycemia on quality of life among adults with type 1 diabetes. BMJ Open Diabetes Research and Care. 2021;9:2322. https://doi.org/10.1136/bmjdrc-2021-002322

The Effect of Fear of Hypoglycemia on Glycemic Control and Quality of Life in Adolescents with Type 1 Diabetes

Yıl 2025, Cilt: 28 Sayı: 3, 233 - 239, 24.09.2025
https://doi.org/10.17049/jnursology.1555373

Öz

Objective: The purpose of this study was to determine the effect of fear of hypoglycemia on glycemic control and quality of life of adolescents with type 1 diabetes.

Methods: This study was conducted as descriptive research. The study was carried out with 117 adolescents aged 13-18 years diagnosed with Type 1 diabetes mellitus. Data were collected between July 2023 and February 2024. Data were collected face-to-face using a personal information form, the Virginia Child/Adolescent Low Blood Glucose Scale and the Quality-of-Life Scale for Children. Pearson correlation analysis and simple linear regression analysis were used to analyze the data obtained from the scales.

Results: In this study, the mean hypoglycemia fear score of adolescents was low (45.15±7.13) and similarly, the mean quality of life score was low (25.48±14.09). There was no significant correlation between fear of hypoglycemia and HbA1c (r = 0.099, P = .288). There was a negative correlation between fear of hypoglycemia and quality of life (r = -0.184; P < .05).

Conclusion: There was no relationship between fear of hypoglycemia and glycemic control, but there was a decrease in quality of life in adolescents with high fear of hypoglycemia. Nurses should evaluate the psychological effects of hypoglycemia while evaluating its physiological effects, allow them to express their fears about diabetes and find solutions to their problems with a multidisciplinary approach.

Etik Beyan

Ethics committee approval was obtained from the Toros University Scientific Research and Publication Ethics Committee with the decision number 128 on 24/06/2022 for the research to grow. Parents provided written consent and children verbal consent before the study.

Destekleyen Kurum

The authors declare that this study had received no financial support.

Teşekkür

We are grateful to all the children and families who participated at the study.

Kaynakça

  • 1. Patterson CC, Karuranga S, Salpea P, et al. Worldwide estimates of incidence, prevalence and mortality of type 1 diabetes in children and adolescents: Results from the International Diabetes Federation Diabetes Atlas, 9th edition. Diabetes Res Clin Pract. 2019;157:107842. https://doi.org/10.1016/j.diabres.2019.107842.
  • 2. American Diabetes Association. 2. Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes-2021. Diabetes Care. 2021;44(Supplement_1):15-33. https://doi.org/10.2337/dc21-S002.
  • 3. Diouri O, Cigler M, Vettoretti M, et al. Hypoglycemia detection and prediction techniques: A systematic review on the latest developments. Diabetes Metab Res Rev. 2021;37(7). https://doi.org/10.1002/dmrr.3449.
  • 4. Abitbol L, Palmert MR. When low blood sugars cause high anxiety: Fear of hypoglycemia among parents of youth with type 1 diabetes mellitus. Can J Diabetes. 2021;45(5):403-410. https://doi.org/10.1016/j.jcjd.2020.08.098.
  • 5. Zhang L, Xu H, Liu L, et al. Related factors associated with fear of hypoglycemia in parents of children and adolescents with type 1 diabetes-A systematic review. J Pediatr Nurs. 2022;66:125-135. https://doi.org/10.1016/j.pedn.2022.05.022.
  • 6. Desjardins K, Brazeau AS, Strychar I, Rabasa-Lhoret R. Are bedtime nutritional strategies effective in preventing nocturnal hypoglycemia in patients with type 1 diabetes? Diabetes Obes Metab. 2014;16(7):577-587. https://doi.org/10.1111/dom.12232.
  • 7. Brazeau AS, Rabasa-Lhoret R, Strychar I, Mircescu H. Barriers to physical activity among patients with type 1 diabetes. Diabetes Care. 2008;31(11):2108-2109. https://doi.org/10.2337/dc08-0720.
  • 8. Przezak A, Bielka W, Molęda P. Fear of hypoglycemia-An underestimated problem. Brain Behav. 2022;12(7):e2633. https://doi.org/10.1002/brb3.2633.
  • 9. Ata SM, Uysal G. Determination of the relationship between fear of hypoglycemia and quality of life in adolescents with diabetes. JAREN. 2022;8(3):131-139. https://doi.org/10.55646/jaren.2022.24650.
  • 10. Brzuszek M, Kochman M, Mazur A. Psychodiabetology: The challenge of the future? J Clin Med. 2024;13(8):2236. https://doi.org/10.3390/jcm13082236.
  • 11. Cooke D, Bond R, Lawton J, et al. Structured type 1 diabetes education delivered within routine care: Impact on glycemic control and diabetes-specific quality of life. Diabetes Care. 2013;36(2):270-272. https://doi.org/10.2337/dc12-0080.
  • 12. Demir G, Akcay N. Diabetes education in children with type 1 diabetes and their families. Turk J Fam Med Prim Care. 2022;16(2):447-455. https://doi.org/10.21763/tjfmpc.936444.
  • 13. Alpar R. Applied statistics and validity and reliability with examples from health and education sciences. Istanbul: Detay; 2010.
  • 14. Gonder-Frederick LA, Fishera CD, Ritterbanda LM, et al. Predictors of fear of hypoglycemia in adolescents with type 1 diabetes and their parent. Pediatr Diabetes. 2006;7:215-222. https://doi.org/10.1111/j.1399-5448.2006.00182.x.
  • 15. Sahin NŞ, Ozcelik CC. University of Virginia child/adolescent low blood glucose scale: Turkish validity and reliability study. J Educ Res Nurs. 2017;14(3):198-203. https://doi.org/10.5222/HEAD.2017.198.
  • 16. Varni JW, Seid M, Rode CA. The PedsQL™: Measurement model for the pediatric quality of life inventory. Med Care. 1999;126-139. https://doi.org/10.1097/00005650-199902000-00003
  • 17. Memik NC, Agaoglu B, Coskun A, Uneri OS, Karakaya I. Validity and reliability of the 13-18 years old adolescent form of the quality of life scale for children. Turk J Psychiatry. 2007;18(4):353-363.
  • 18. Mayers A. Introduction to statistics and SPSS in psychology. Pearson; 2013.
  • 19. Khunti K, Alsifri S, Aronson R, et al. Impact of hypoglycemia on patient-reported outcomes from a global, 24-country study of 27,585 people with type 1 and insulin-treated type 2 diabetes. Diabetes Res Clin Pract. 2017;130:121-129. https://doi.org/10.1016/j.diabres.2017.05.004.
  • 20. Strandberg RB, Graue M, Wentzel-Larsen T, et al. The relationships among fear of hypoglycemia, diabetes-related quality of life and psychological well-being in Norwegian adults with type 1 diabetes. Diabetes Res Clin Pract. 2017;124:11-19. https://doi.org/10.1016/j.diabres.2016.12.018.
  • 21. Gül S, Asiret GD, Okatan C. Investigation of hypoglycemia fear of individuals with type 2 diabetes mellitus. Dokuz Eylul Univ Fac Nurs Electron J. 2021;14(3):179-187. https://doi.org/10.46483/deuhfed.825712.
  • 22. Glocker V, Bachmann S, Hess M, Szinnai G, Burckhardt MA. Fear of hypoglycemia and quality of life in young people with type 1 diabetes and their parents in the era of sensor glucose monitoring. Front Endocrinol (Lausanne). 2022;13:958671. https://doi.org/10.3389/fendo.2022.958671.
  • 23. Zeitoun MH, Reheem AAA, Kharboush IF, et al. Relationship between depressive and anxiety symptoms and fear of hypoglycemia among adolescents and adults with type 1 diabetes mellitus. Prim Care Diabetes. 2023;17(3):255-259. https://doi.org/10.1016/j.pcd.2023.03.002.
  • 24. Ng SM, Moore HS, Clemente MF, Pintus D, Soni A. Continuous glucose monitoring in children with type 1 diabetes improves well-being, alleviates worry and fear of hypoglycemia. Diabetes Technol Ther. 2019;21(3):133-137. https://doi.org/10.1089/dia.2018.0347.
  • 25. Souza MA, Freitas RWJF, Lima LS, et al. Health-related quality of life of adolescents with type 1 diabetes mellitus. Rev Lat Am Enfermagem. 2019;27:e3210. https://doi.org/10.1590/1518-8345.2961.3210.
  • 26. Marques RDM, Rodrigues ML, Santos CR, et al. Associated factors with the quality of life of adolescents with type 1 diabetes. Clin Nutr ESPEN. 2021;42:387-392. https://doi.org/10.1016/j.clnesp.2020.12.018.
  • 27. Saulnier PJ, Briet C, Gand E, et al. No association between fear of hypoglycemia and blood glucose variability in type 1 diabetes: The cross-sectional VARDIA study. J Diabetes Complications. 2019;33(8):554-560. https://doi.org/10.1016/j.jdiacomp.2019.05.003.
  • 28. Andreopoulou O, Kostopoulou E, Kotanidou E, et al. Evaluation of the possible impact of the fear of hypoglycemia on diabetes management in children and adolescents with type 1 diabetes mellitus and their parents: A cross-sectional study. Hormones (Athens). 2024;23(3):419-428. https://doi.org/10.1007/s42000-024-00560-z.
  • 29. Johnson SR, Cooper MN, Davis EA, Jones TW. Hypoglycemia, fear of hypoglycemia and quality of life in children with type 1 diabetes and their parents. Diabet Med. 2013;30(9):1126-1131. https://doi.org/10.1111/dme.12247.
  • 30. Shepard JA, Vajda K, Nyer M, Clarke W, Gonder-Frederick L. Understanding the structure of fear of hypoglycemia in paediatric type 1 diabetes. J Pediatr Psychol. 2014;39(10):1115-1125. https://doi.org/10.1093/jpepsy/jsu069.
  • 31. Amiri F, Vafa M, Gonder-Frederick L. Glycemic Control, Self-Efficacy and Fear of Hypoglycemia among Iranian children with type 1 diabetes. Can J Diabetes. 2015;39:302-307. https://doi.org/10.1016/j.jcjd.2014.12.011
  • 32. Chatwin H, Broadley M, Valdersdorf Jensen M, et al. ‘Never again will I be carefree’: a qualitative study of the impact of hypoglycemia on quality of life among adults with type 1 diabetes. BMJ Open Diabetes Research and Care. 2021;9:2322. https://doi.org/10.1136/bmjdrc-2021-002322
Toplam 32 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Çocuk Sağlığı ve Hastalıkları Hemşireliği
Bölüm Araştırma Makaleleri
Yazarlar

Didem Polat Külcü 0000-0002-2535-349X

Melek Gülgün Altıntaş 0000-0001-5085-3747

Ayda Çelebioğlu 0000-0002-5610-9801

Erken Görünüm Tarihi 4 Eylül 2025
Yayımlanma Tarihi 24 Eylül 2025
Gönderilme Tarihi 25 Eylül 2024
Kabul Tarihi 21 Nisan 2025
Yayımlandığı Sayı Yıl 2025 Cilt: 28 Sayı: 3

Kaynak Göster

AMA Polat Külcü D, Gülgün Altıntaş M, Çelebioğlu A. The Effect of Fear of Hypoglycemia on Glycemic Control and Quality of Life in Adolescents with Type 1 Diabetes. Journal of Nursology. Eylül 2025;28(3):233-239. doi:10.17049/jnursology.1555373

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