Long term results of arterial revascularization with Omniflow II biosynthetic grafts: a single center experience

Abstract

Objective: The aim of this study is to analyze the long-term outcomes of above-knee femoro-popliteal bypass procedures with Omniflow II biosynthetic grafts. Primary patency and graft related complications were the end points of the study. Methods: Between January 2012 and January 2021, a total of 50 patients (42 males, 8 females) were revascularized using an in-situ Omniflow II graft. Demographic, clinical, operative and postoperative characteristics of the patients were analyzed retrospectively. Results: Mean age was 63.8±10.1 (range 40-82) years. Fifty above-knee femoropopliteal bypass procedures were performed. Four patients (8%) were operated on due to a previous vascular graft infection where 8 (16%) were operated on due to a previous occlusion. Primary patency rate was 88%. Early graft thrombosis occurred in 2 (4%) patients where late graft stenosis unrelated to the anastomotic sites was encountered in 1 (2%) patient. An endarterectomy on either the proximal or distal site of the anastomosis were performed in 12 (24%) patients. Mean follow-up was 32.9±20.8 (range 12-90) months. Three (6%) patients died due to a COVID-19 infection. No graft infection nor mortality related to arterial bypass procedures was encountered. Conclusion: The Omniflow II biosynthetic graft provides superior results in treatment of above-knee femoro-popliteal bypass procedures with high patency rates and low incidence of graft infection and aneurysm formation

Keywords

• : Biosynthetic graft
• vascular grafting
• revascularization
• peripheral arterial disease

Omniflow II biyosentetik greftlerle arteriyel revaskülarizasyonun uzun dönem sonuçları: tek merkez deneyimi

Öz

Giriş: Bu çalışmanın amacı, Omniflow II biyosentetik greftlerle diz üstü femoropopliteal baypas prosedürlerinin uzun dönem sonuçlarını analiz etmektir. Primer açıklık oranları ve greft ile ilişkili komplikasyonlar çalışmanın ana hedefleri olarak belirlendi. Gereç ve Yöntemler: Ocak 2012 ile Ocak 2021 arasında, toplam 50 hasta (42 erkek, 8 kadın) in- situ Omniflow II greft kullanılarak revaskülarize edildi. Hastaların demografik, klinik, operatif ve postoperatif özellikleri retrospektif olarak incelendi. Sonuç: Ortalama yaş 63.8±10.1 (dağılım 40-82) idi. Elli hastaya diz üstü femoropopliteal bypass operasyonu yapıldı. Dört hasta (%8) vasküler greft enfeksiyonu nedeniyle ameliyat edilirken, 8 hasta (%16) oklüde olmuş eski greftler nedeniyle ameliyat edildi. Primer açıklık oranı %88 idi. Erken greft trombozu 2 (%4) hastada görülürken, 1 (%2) hastada proksimal ya da distal anastomoz bölgeleriyle ilgisi olmayan geç dönem greft darlığına rastlandı. 12 (%24) hastaya anastomozun proksimal veya distal bölgesinde endarterektomi uygulandı. Ortalama takip süresi 32.9±20.8 ay (dağılım 12-90) idi. Üç hasta (%6) COVID-19 enfeksiyonu nedeniyle hayatını kaybetti. Greft enfeksiyonu veya arteriyel baypas prosedürlerine bağlı mortalite ile karşılaşılmadı. Tartışma: Omniflow II biyosentetik greft, diz üstü femoropopliteal baypas prosedürlerinde yüksek açıklık oranları, düşük greft enfeksiyonu ve anevrizma oluşumu insidansı ile üstün ve başarılı sonuçlar vermektedir.

Anahtar Kelimeler

• Biyosentetik gerft
• vasküler greft
• revaskülarizasyon
• periferik arter hastalığı

Kaynakça

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