Implant and Immunity in Neurosurgery

Öz

Biological implants are widely used in neurosurgical operations especially in spine surgery. Many non-allergen metal implants have been developed such as titanium. Allergies agains other metal implants such as nickel, cobalt, and chrome, are common in the general population. Allergic reactions could cause complications such as intense pain, excessive inflammation, or rejection of implanted material/tissue. Implant life period depends on tissue implant reactions. Natural immunity and adaptive immune responses play a part in inflamatory reactions. Diagnostic tests could be done for metal implants allegy. In conclusion, if the titanium hypersensitivity reaction is proven, the definitive treatment is the removal of the device.

Anahtar Kelimeler

• Allergy,implant,immunity

Nöroşirurjide İmplant ve İmmünite

Öz

Biyolojik implantlar, nöroşirürji operasyonları, özellikle omurga cerrahisinde yaygın olarak kullanılır. Titanyum gibi alerjik olmayan birçok metal implant geliştirilmiştir. Nikel, kobalt ve krom gibi diğer metal implantlara karşı alerjiler, genel popülasyonda yaygındır. Alerjik reaksiyonlar, şiddetli ağrı, aşırı iltihaplanma veya implant materyalin dokunun reddi gibi komplikasyonlara neden olabilir. İmplant ömrü, doku implantı reaksiyonlarına bağlıdır. Doğal bağışıklık ve adaptif bağışıklık tepkileri, enflamatuar reaksiyonlarda rol oynar. Metal implantları için tanı amaçlı testler yapılabilir. Sonuç olarak, eğer titanyum aşırı duyarlılık reaksiyonu kanıtlanmışsa kesin tedavi cihazın çıkarılmasıdır.

Anahtar Kelimeler

• Alerji,implant,immünite

Kaynakça

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