Prognostic evaluation of newborns with neonatal hyperbilirubinemia

Yıl 2023, , 690 - 693, 31.12.2023

Özlem Özcanlı Çay , Özlem Kemer

https://doi.org/10.47582/jompac.1398442

Öz

Aims: We aimed to investigate the effect of phototherapy treatment by showing that it increases systemic inflammation and changes in NLR (neutrophil count/lymphocyte count), PLO (platelet count/lymphocyte count), systemic Inflammation Index (platelet count × neutrophil count/lymphocyte count ratio) in peripheral blood.
Methods: It was conducted at Balıkesir University Health Practice and Research Hospital between April 2023 and August 2023. 60 babies with a gestational age of ≥36 weeks and a birth weight of ≥2500 g were included in the study.
Results: A statistically significant difference was detected between WBC, lymphocyte count, monocyte count, neutrophil count, lymphocyte/monocyte, systemic inflammatory index before and after phototherapy (p<0.05).
Conclusion: We concluded that phototherapy is associated with the inflammatory process and may increase cytokine release. To investigate these effects of phototherapy, studies on larger populations are needed.

Anahtar Kelimeler

Neonatal jaundice, systemic inflammatory index, phototherapy

Prognostic evaluation of newborns with neonatal hyperbilirubinemia

Öz

Amaç: Fototerapi tedavisinin sistemik inflamasyonu ve NLR (Nötrofil sayısı/Lenfosit sayısı), PLO (Platelet sayısı/Lenfosit sayısı), Sistemik İnflamasyon İndeksindeki (Platelet sayısı x Nötrofil sayısı/Lenfosit sayısı) değişiklikleri artırdığını göstererek etkisini araştırmayı amaçladık. sayım oranı) periferik kanda.
Yöntemler : …… Üniversitesi Sağlık Uygulama ve Araştırma Hastanesi'nde Nisan 2023-Ağustos 2023 tarihleri arasında gerçekleştirildi. Çalışmaya gebelik yaşı ≥36 hafta ve doğum ağırlığı ≥2500 g olan 60 bebek dahil edildi.
Bulgular: Fototerapi öncesi ve sonrası WBC, lenfosit sayısı, monosit sayısı, nötrofil sayısı, lenfosit/monosit, sistemik inflamatuar indeks arasında istatistiksel olarak anlamlı fark tespit edildi (p<0,05).
Sonuç: Fototerapinin inflamatuar süreçle ilişkili olduğu ve sitokin salınımını artırabileceği sonucuna vardık. Fototerapinin bu etkilerini araştırmak için daha büyük popülasyonlarda çalışmalara ihtiyaç vardır.

Anahtar Kelimeler

Yenidoğan sarılığı, sistemik inflamatuar indeks, fototerapi

Kaynakça

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