Holistic analysis of hepatosteatosis literature: a scientometric study of global hepatosteatosis publications between 1980 and 2019

Year 2022, Volume: 3 Issue: 4, 300 - 305, 26.12.2022

Fatih Eskin , Engin Şenel

https://doi.org/10.47582/jompac.1172446

Cited By: 3

Abstract

Aim: Hepatosteatosis is a subtype of Non-Alcoholic Fatty Liver Disease (NAFLD) with an increased significance and prevalence in recent years, progressing to chronic liver disease and even hepatocellular carcinoma. It has become the new focus of hepatology instead of viral hepatitis in the last 5 years because of its increasing prevalence and close association with metabolic diseases such as obesity, diabetes and hyperlipidemia. The present study aimed to make a holistic scientometric analysis of scientific studies conducted on hepatosteatosis.
Material and Method: We analyzed scientometric analysis of “hepatosteatosis” publications that were indexed in Web of Science databases between 1980 and 2019 and found a total of 996 articles.
Results: The most published documents were original articles (80.924%). The most investigated areas in the hepatosteatosis literature were found to be gastroenterology, biochemistry and endocrinology (n=751, 687 and 575 documents, respectively). The USA was the leading country with 371 articles, followed by Turkey, China, Japan, Italy and Germany (n=146, 145, 81 and 58 articles, respectively). Zhang Yen was found to be the most productive author from Yanbian University (China) and California University was the most productive institution. The hepatosteatosis literature H-index was measured as 76, with an average of 24.8 citations per item and a total of 24.705 citations. The most indexed keywords were found to be “hepatosteatosis”, “fatty liver”, “obesity” and “insulin resistance”. The USA, China, UK, Germany and Italy were found to be the most cooperating countries.
Conclusion: Hepatosteatosis is an issue with increased importance and popularity with the intense interest of researchers in the past few years. The data of the present study, in which the scientometric analysis of the studies on hepatosteatosis was performed, emphasized the importance of the subject once again and will guide researchers for new researches to be conducted on many subjects such as which countries, institutions, individuals and journals are more interested in hepatosteatosis, and in which areas the studies are concentrated. To the best of our knowledge, it is the first scientometric study evaluating hepatosteatosis.

Keywords

Hepatosteatosis, holistic analisis, metabolic disorders, scientometric

Hepatosteatoz literatürün bütünsel analizi: 1980 ve 2019 arasındaki küresel hepatosteatoz yayınlarının scientometrik çalışması

Abstract

Amaç: Hepatosteatoz, son yıllarda önemi ve prevalansı artan, kronik karaciğer hastalığına ve hatta hepatosellüler karsinomaya ilerleyen Alkolsüz Yağlı Karaciğer Hastalığı’nın (NAFLD) bir alt tipidir. Artan prevalansı ve obezite, diyabet, hiperlipidemi gibi metabolik hastalıklarla yakın ilişkisi nedeniyle son 5 yılda viral hepatit yerine hepatolojinin yeni odağı haline gelmiştir. Bu çalışma, hepatosteatoz ile ilgili yapılan bilimsel çalışmaların bütüncül bir scientometrik analizini yapmayı amaçlamıştır.
Gereç ve Yöntem: 1980 ile 2019 yılları arasında Web of Science veri tabanlarında indekslenen “hepatosteatoz” yayınlarının scientometrik analizini inceledik ve toplam 996 makale bulduk.
Bulgular: En çok yayınlanan dökümanlar orijinal makalelerdi (%80,924). Hepatosteatoz literatüründe en çok araştırılan alanların gastroenteroloji, biyokimya ve endokrinoloji olduğu bulundu (sırasıyla n=751, 687 ve 575 döküman). ABD 371 makale ile lider ülke olurken, onu Türkiye, Çin, Japonya, İtalya ve Almanya takip etti (sırasıyla n=146, 145, 81 ve 58 makale). Zhang Yen’in Yanbian Üniversitesi’nden (Çin) en üretken yazar olduğu ve California Üniversitesi’nin en üretken kurum olduğu tespit edildi. Hepatosteatoz literatür H-indeksi madde başına ortalama 24,8 ve toplam 24.705 atıf ile 76 olarak ölçüldü. En çok indekslenen anahtar kelimelerin “hepatosteatoz”, “yağlı karaciğer”, “obezite” ve “insülin direnci” olduğu bulundu. ABD, Çin, İngiltere, Almanya ve İtalya en çok işbirliği yapılan ülkeler olarak belirlendi.
Sonuç: Hepatosteatoz, son birkaç yıldır araştırmacıların yoğun ilgi göstermesi ile birlikte önemi ve popülaritesi artmış bir konudur. Hepatosteatoz üzerine yapılan araştırmaların scientometrik analizinin yapıldığı bu çalışmanın verileri, konunun önemini bir kez daha vurgulamış ve hepatosteatoz ile hangi ülke, kurum, kişi ve dergilerin daha çok ilgilendikleri ve araştırmaların hangi alanlarda yoğunlaştığı gibi pek çok konuda araştırmacılara yapılacak yeni araştırmalar için yol gösterici olacaktır. Bildiğimiz kadarıyla da hepatosteatozu değerlendiren ilk scientometric çalışmadır.

Keywords

Hepatosteatozis, bütünsel analiz, metabolik bozukluklar, scientometrik

Supporting Institution

Destekleyen kurum yok

References

• Wei S, Liu S, Su X, et al. Spontaneous development of hepatosteatosis in perilipin-1 null mice with adipose tissue dysfunction. Biochim Biophys Acta Mol Cell Biol Lipids 2018; 1863: 212-8.
• Obika M, Noguchi H. Diagnosis and evaluation of nonalcoholic fatty liver disease. Exp Diabetes Res 2012; 2012: 145754.
• Garg A. Adipose tissue dysfunction in obesity and lipodystrophy. Clin Cornerstone 2006; 8: 7-13.
• Liaqat M, Fatima M, Malik SS, Gillani SA, Manzoor I. Ultrasonographic features associated with diffuse hepatosteatosis among diabetic obese and normal body mass index patients. J Med Ultrasound 2020; 28: 235-8.
• Matteoni CA, Younossi ZM, Gramlich T, Boparai N, Liu YC, McCullough AJ. Nonalcoholic fatty liver disease: A spectrum of clinical and pathological severity. Gastroenterology 1999; 116: 1413-9.
• Bhatt HB, Smith RJ. Fatty liver disease in diabetes mellitus. Hepatobiliary Surg Nutr 2015; 4: 101–8.
• Rhee EJ. Nonalcoholic fatty liver disease and diabetes: An epidemiological perspective. Endocrinol Metab (Seoul) 2019; 34: 226-33.
• Chalasani N, Younossi Z, Lavine JE, et al. The diagnosis and management of non-alcoholic fatty liver disease: practice guideline by the American Gastroenterological Association, American Association for the Study of Liver Diseases, and American College of Gastroenterology. Gastroenterology 2012; 142: 1592–609.
• Das K, Das K, Mukherjee PS, et al. Nonobese population in a developing country has a high prevalence of nonalcoholic fatty liver and significant liver disease. Hepatology 2010; 51: 1593–02.
• Patton HM, Lavine JE. Focal fatty liver: More than just a radiographic curiosity? Gastroenterol Hepatol (N Y) 2007; 3: 199–200.
• World Health Organization. Global health sector strategy on viral hepatitis, 2016–2021. Geneva: 2016. Available at: http: //apps.who.int/iris/bitstream/10665/246177/1/WHO-HIV2016.06-eng.pdf?ua=1
• Şenel E. The last three decades of contact dermatitis: A bibliometric analysis of global publications on contact dermatitis. J Dermatol Nurses Assoc 2020; 12: 223-31.
• GunnMap. GunnMap 2 [www Document]. URL http: //lert.co.nz/map/ [accessed on 10 January 2020].
• Vosviewer. VOSviewer - Visualizing scientific landscapes. URL https: //www.vosviewer.com/ [accessed on 10 January 2020].
• Chalasani N, Younossi Z, Lavine JE, et al. The diagnosis and management of non-alcoholic fatty liver disease: Practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association. Hepatology 2012; 55: 2005-23.
• Trifan A, Stanciu C, Jurcău M, Zenovia S, Frunzuc G, Timofte D. Nonalcoholic steatohepatitis: A scientometric analysis of publications during 1980-2018. Medicine (Baltimore) 2019; 98: e18221.
• Bhupathiraju SN, Hu FB. Epidemiology of obesity and diabetes and their cardiovascular complications. Circ Res 2016; 118: 1723-35.
• Arroyo-Johnson C, Mincey KD. Obesity epidemiology worldwide. Gastroenterol Clin North Am 2016; 45: 571-9.