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Pediatrik yoğun bakım ünitesindeki kritik hasta çocukların profili: üçüncü basamak tek merkezli bir deneyim

Year 2023, Volume: 4 Issue: 3, 224 - 228, 28.06.2023
https://doi.org/10.47582/jompac.1284165

Abstract

Amaç: Üçüncü basamak çocuk yoğun bakım ünitesine (ÇYBÜ) yatırılan kritik hasta çocukların klinik spektrumunu ve sonuçlarını bildirerek, ÇYBÜ ihtiyacında etkili olabilecek faktörleri değerlendirmek, erken tanı ve tedavi yanıtına yardımcı olarak olası ÇYBÜ ihtiyacı.hasta sayısını azaltmayı amaçladık.
Gereç ve Yöntem: Sancaktepe Şehit Prof. Dr. İlhan Varank Eğitim ve Araştırma Hastanesi'nde Şubat 2022-Ocak 2023 tarihleri arasında ÇYBÜ'ye kritik hastalıklarla başvuran 1 ay-18 yaş arası tüm çocukların dahil edildiği tanımlayıcı tipte bir çalışma yapılmıştır. Demografik veriler, klinik değişkenler ve sonuç verileri (canlı/ölü) analiz edildi.
Bulgular: 258 (%56,6) erkek ve 198 (%43,4) kadın olmak üzere toplam 456 hasta analiz edildi. ÇYBÜ'de ortanca kalış süresi 5 gündü (1-114). Yoğun bakım ünitesine en sık başvuru nedeni solunum yolu hastalıkları (%43,2), bunu sepsis (%13,2) ve nörolojik hastalıklar (%13,8) izledi. Yaş veya cinsiyetle ilişkisi olmayan %6,1'lik bir ölüm oranı gözlemledik. Mortalite için risk faktörü olarak bulunan değişkenler PRISM III skoru, sepsis ve akut böbrek yetmezliği varlığı, mekanik ventilasyon gereksinimi, inotropik ajan kullanımı, sürekli renal replasman tedavisi ve terapötik plazma değişimi gereksinimi ve yatış süresi idi (p < 0.001).
Sonuç: ÇYBÜ'ye kabul edilen hastaların profili, yoğun bakım için özel protokoller geliştirmek ve ÇYBÜ'lerin kaynaklarını yeniden dağıtmak için bir temel oluşturabilir.

References

  • You D, Hug L, Ejdemyr S, et al. Global, regional, and national levels and trends in under-5 mortality between 1990 and 2015, with scenario-based projections to 2030: a systematic analysis by the UN Inter-agency Group for Child Mortality Estimation. Lancet. 2015;386(10010):2275-2286. doi:10.1016/S0140-6736(15)00120-8
  • Downes JJ. The historical evolution, current status, and prospective development of pediatric critical care. Crit Care Clin. 1992;8(1):1-22.
  • Earan SK, Dhandapani L, Arunagirinathan A, Kantamneni. Clinical spectrum and epidemiological profile of patients admitted to pediatric intensive care unit at a tertiary care centre in South India. Int J Scientific Study. 2016;4:187-191.
  • Pollack MM, Patel KM, Ruttimann UE. PRISM III: an updated Pediatric Risk of Mortality score. Crit Care Med. 1996;24(5):743-752. doi:10.1097/00003246-199605000-00004
  • Lanetzki CS, de Oliveira CA, Bass LM, Abramovici S, Troster EJ. The epidemiological profile of pediatric intensive care center at hospital Israelita Albert Einstein. Einstein (Sao Paulo). 2012;10(1):16-21. doi:10.1590/s1679-45082012000100005
  • Sahoo B, Patnaik S, Mishra R, Jain MK. Morbidity pattern and outcome of children admitted to a paediatric intensive care unit of Eastern India. Int J Contemp Pediatr. 2017;4:486-489. doi: 10.18203/2349-3291.ijcp20170694
  • Blessing I, Iyoha A, Pooboni SK,Vuppali NK. Morbidity pattern and outcome of patients admitted into a pediatric intensive care unit in India. Ind J Clin Med. 2014;5;51-55.
  • Haque A, Bano S. Clinical profile and outcome in a paediatric intensive care unit in Pakistan. J Coll Physicians Surg Pak. 2009;19(8):534-535.
  • Yeğin LN, Sancak Y, Aşut Ç, Gizem Z, Özdel E. Çocuk yoğunbakım ünitesine yatan hastaların değerlendirilmesi /Evaluation of the patients admitted to the pediatric intensive care unit. Güncel Pediatri. 2017; 15:1-10.
  • El-Nawawy A. Evaluation of the outcome of patients admitted to the pediatric intensive care unit in Alexandria using the pediatric risk of mortality (PRISM) score. J Trop Pediatr. 2003;49(2):109-114. doi:10.1093/tropej/49.2.109
  • Rady HI. Profile of patients admitted to pediatric intensive care unit, Cairo University Hospital: 1-year study. Ain-Shams J Anaesthesiology. 2014;7:500.
  • Poyrazoğlu H, Dursun İ, Güneş T, et al. Çocuk yoğunbakım ünitesine yatan olguların değerlendirilmesi ve sonuçları. Erciyes Med J /Erciyes Tip Derg. 2008;30:232-237.
  • Gonçalves JP, Severo M, Rocha C, Jardim J, Mota T, Ribeiro A. Performance of PRISM III and PELOD-2 scores in a pediatric intensive care unit. Eur J Pediatr. 2015;174:1305-1310.
  • Volakli EA, Sdougka M, Drossou-Agakidou V, Emporiadou M, Reizoglou M, Giala M. Short-term and long-term mortality following pediatric intensive care. Pediatr Int. 2012;54(2):248-255. doi:10.1111/j.1442-200X.2011.03545.x
  • Kılıç FZ, Çoban Y, Davutoğlu M, Dalkıran T. Çocuk yoğunbakım ünitesinde izlenen hastaların geriye dönük analizi ve mortaliteyi etkileyen faktörlerin incelenmesi. J Pediatr Emerg Intens Care Med. 2016; 3: 140-5.
  • Krishnan J, Morrison W, Simone S, Ackerman A. Implications of thrombocytopenia and platelet course on pediatric intensive care unit outcomes. Pediatr Crit Care Med. 2008;9(5):502-505. doi:10.1097/PCC.0b013e3181849af1
  • Özdemir H, Kantar A, Coşkun E, Dinlen N, Özyörük D, Metin A. Yeni açılan çocuk yoğunbakım birimimizdeki mekanik vantilasyon uygulamalarımızın ilk sonuçları. Turk Arch Pediatr. 2008;43:3.
  • Kristensen K, Andersen EA, Andersen MH, et al. A three year population based survey of paediatric mechanical ventilation in east Denmark. Dan Med Bull. 2002;49(1):67-69.
  • Wang Z, He Y, Zhang X, Luo Z. Non-invasive ventilation strategies in children with acute lower respiratory infection: a systematic review and Bayesian network meta-analysis. Front Pediatr. 2021;9:749975. doi:10.3389/fped.2021.749975
  • Boghi D, Kim KW, Kim JH, et al. Noninvasive ventilation for acute respiratory failure in pediatric patients: a systematic review and meta-analysis. Pediatr Crit Care Med. 2023;24(2):123-132. doi:10.1097/PCC.0000000000003109

Profile of critically ill childrenin the pediatric intensive care unit: a tertiary-care single-center experience

Year 2023, Volume: 4 Issue: 3, 224 - 228, 28.06.2023
https://doi.org/10.47582/jompac.1284165

Abstract

Aims: The aim of this study was to present a comprehensive overview of the clinical spectrum and outcomes of critically ill pediatric patients admitted to a tertiary-level pediatric intensive care unit (PICU). Furthermore, we aimed to assess potential factors that could influence the requirement for PICU admission. The findings of this study may aid in the prompt identification and management of critically ill pediatric patients, thereby reducing the likelihood of PICU admission.
Methods: This descriptive study investigated the presentation of critical illness among pediatric patients aged between 1 month-18 years old admitted to the PICU was conducted in Sancaktepe Sehit Prof. Dr. İlhan Varank Training and Research Hospital, from February 2022 to January 2023. Demographic data, clinical variables, and outcome data (alive/expired) were analyzed.
Results: A total of 456 patients were analyzed, of which 258 (56.6%) were males and 198 (43.4%) were females. The median length of stay in the PICU was 5 days (1-114). Respiratory diseases (43.2%) were the most common reasons for admission to the PICU, followed by sepsis (13.2%), and neurological diseases (13.8%). We observed a mortality rate of 6.1%, with no association with age or sex. Variables found to be risk factors for mortality were PRISM III score, presence of sepsis and acute renal failure, the requirement for mechanical ventilation, use of inotropic agents, continuous renal replacement therapy and therapeutic plasma exchange requirement, and length of stay (p < 0.001).
Conclusion: The profile of patients admitted to the PICU can serve as a basis for developing dedicated protocols for critical care and redistributing the PICUs’ resources.

References

  • You D, Hug L, Ejdemyr S, et al. Global, regional, and national levels and trends in under-5 mortality between 1990 and 2015, with scenario-based projections to 2030: a systematic analysis by the UN Inter-agency Group for Child Mortality Estimation. Lancet. 2015;386(10010):2275-2286. doi:10.1016/S0140-6736(15)00120-8
  • Downes JJ. The historical evolution, current status, and prospective development of pediatric critical care. Crit Care Clin. 1992;8(1):1-22.
  • Earan SK, Dhandapani L, Arunagirinathan A, Kantamneni. Clinical spectrum and epidemiological profile of patients admitted to pediatric intensive care unit at a tertiary care centre in South India. Int J Scientific Study. 2016;4:187-191.
  • Pollack MM, Patel KM, Ruttimann UE. PRISM III: an updated Pediatric Risk of Mortality score. Crit Care Med. 1996;24(5):743-752. doi:10.1097/00003246-199605000-00004
  • Lanetzki CS, de Oliveira CA, Bass LM, Abramovici S, Troster EJ. The epidemiological profile of pediatric intensive care center at hospital Israelita Albert Einstein. Einstein (Sao Paulo). 2012;10(1):16-21. doi:10.1590/s1679-45082012000100005
  • Sahoo B, Patnaik S, Mishra R, Jain MK. Morbidity pattern and outcome of children admitted to a paediatric intensive care unit of Eastern India. Int J Contemp Pediatr. 2017;4:486-489. doi: 10.18203/2349-3291.ijcp20170694
  • Blessing I, Iyoha A, Pooboni SK,Vuppali NK. Morbidity pattern and outcome of patients admitted into a pediatric intensive care unit in India. Ind J Clin Med. 2014;5;51-55.
  • Haque A, Bano S. Clinical profile and outcome in a paediatric intensive care unit in Pakistan. J Coll Physicians Surg Pak. 2009;19(8):534-535.
  • Yeğin LN, Sancak Y, Aşut Ç, Gizem Z, Özdel E. Çocuk yoğunbakım ünitesine yatan hastaların değerlendirilmesi /Evaluation of the patients admitted to the pediatric intensive care unit. Güncel Pediatri. 2017; 15:1-10.
  • El-Nawawy A. Evaluation of the outcome of patients admitted to the pediatric intensive care unit in Alexandria using the pediatric risk of mortality (PRISM) score. J Trop Pediatr. 2003;49(2):109-114. doi:10.1093/tropej/49.2.109
  • Rady HI. Profile of patients admitted to pediatric intensive care unit, Cairo University Hospital: 1-year study. Ain-Shams J Anaesthesiology. 2014;7:500.
  • Poyrazoğlu H, Dursun İ, Güneş T, et al. Çocuk yoğunbakım ünitesine yatan olguların değerlendirilmesi ve sonuçları. Erciyes Med J /Erciyes Tip Derg. 2008;30:232-237.
  • Gonçalves JP, Severo M, Rocha C, Jardim J, Mota T, Ribeiro A. Performance of PRISM III and PELOD-2 scores in a pediatric intensive care unit. Eur J Pediatr. 2015;174:1305-1310.
  • Volakli EA, Sdougka M, Drossou-Agakidou V, Emporiadou M, Reizoglou M, Giala M. Short-term and long-term mortality following pediatric intensive care. Pediatr Int. 2012;54(2):248-255. doi:10.1111/j.1442-200X.2011.03545.x
  • Kılıç FZ, Çoban Y, Davutoğlu M, Dalkıran T. Çocuk yoğunbakım ünitesinde izlenen hastaların geriye dönük analizi ve mortaliteyi etkileyen faktörlerin incelenmesi. J Pediatr Emerg Intens Care Med. 2016; 3: 140-5.
  • Krishnan J, Morrison W, Simone S, Ackerman A. Implications of thrombocytopenia and platelet course on pediatric intensive care unit outcomes. Pediatr Crit Care Med. 2008;9(5):502-505. doi:10.1097/PCC.0b013e3181849af1
  • Özdemir H, Kantar A, Coşkun E, Dinlen N, Özyörük D, Metin A. Yeni açılan çocuk yoğunbakım birimimizdeki mekanik vantilasyon uygulamalarımızın ilk sonuçları. Turk Arch Pediatr. 2008;43:3.
  • Kristensen K, Andersen EA, Andersen MH, et al. A three year population based survey of paediatric mechanical ventilation in east Denmark. Dan Med Bull. 2002;49(1):67-69.
  • Wang Z, He Y, Zhang X, Luo Z. Non-invasive ventilation strategies in children with acute lower respiratory infection: a systematic review and Bayesian network meta-analysis. Front Pediatr. 2021;9:749975. doi:10.3389/fped.2021.749975
  • Boghi D, Kim KW, Kim JH, et al. Noninvasive ventilation for acute respiratory failure in pediatric patients: a systematic review and meta-analysis. Pediatr Crit Care Med. 2023;24(2):123-132. doi:10.1097/PCC.0000000000003109
There are 20 citations in total.

Details

Primary Language English
Subjects Pediatric Intensive Care , Health Care Administration
Journal Section Research Articles [en] Araştırma Makaleleri [tr]
Authors

Cansu Durak

Ebru Şahin

Yasar Yusuf Can 0000-0002-1767-1551

Kübra Boydağ Güvenç

Alican Sarısaltık 0000-0002-7317-404X

Fatih Varol

Halit Cam

Publication Date June 28, 2023
Published in Issue Year 2023 Volume: 4 Issue: 3

Cite

AMA Durak C, Şahin E, Can YY, Boydağ Güvenç K, Sarısaltık A, Varol F, Cam H. Profile of critically ill childrenin the pediatric intensive care unit: a tertiary-care single-center experience. J Med Palliat Care / JOMPAC / jompac. June 2023;4(3):224-228. doi:10.47582/jompac.1284165

TR DİZİN ULAKBİM and International Indexes (1d)

Interuniversity Board (UAK) Equivalency: Article published in Ulakbim TR Index journal [10 POINTS], and Article published in other (excuding 1a, b, c) international indexed journal (1d) [5 POINTS]



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