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Biological activities of bee products of Bingöl province and its region

Yıl 2022, Cilt: 1 Sayı: 3, 170 - 180, 23.12.2022

Yusuf Karagözoğlu , Tuğba Raika Kıran

Öz

Honey, propolis, bee pollen, royal jelly, bee bread, bee venom and beeswax are products produced by bees. Honey is a sweet viscous secretion collected from beehives and found in the cells of honey bee combs. Propolis is a resinous substance that bees collect from the leaves and buds of plants. Bee pollen is a mixture of flower pollen collected by the Apis mellifera L. honey bee with nectar and bee secretions. Bee products, which have various biological properties such as antimicrobial, anti-inflammatory, anticancer and antioxidant activities, are natural products that are important for health and have high nutritional value.
Bingöl is a very suitable region for beekeeping potential in terms of its vegetation and geographical conditions. Milkvetch, clover and vetch plants, which are from the Fabaceae family most preferred by bees, grow in the Bingöl flora. In addition, Asteraceae, Lamiaceae are among the other family groups that collect the most nectar in this region. In the study, the effect of location difference and plant species on chemical parameters, vitamin, fatty acid, element content, antioxidant, antimicrobial and anticancer activity in honey, bee pollen and propolis samples obtained from different locations of Bingöl were evaluated.

Anahtar Kelimeler

Bee Products Bingöl Antioxidant Antimicrobial Anticancer

Kaynakça

  • Akkol, E.K., Orhan, D.D., Gürbüz, I. & Yesilada, E. (2010). In vivo activity assessment of a “honey-bee pollen mix” formulation, Pharmaceutical Biology, 48(3), 253-259.
  • Aksoy, Z. & Dığrak M. (2006). Bingöl yöresinde toplanan bal ve propolisin antimikrobiyal etkisi üzerinde in-vitro araştırmalar. Fırat Üniversitesi Fen ve Mühendislik Fakültesi Dergisi, 18(4), 471-478.
  • Alayunt, N.Ö., Karagözoğlu, Y. & Kutlu, M.A. (2012). Bingöl’den toplanan arı polenlerinde malondialdehid düzeylerinin iki farklı yöntemle belirlenmesi. Bitlis Eren Üniversitesi Fen Bilimleri Dergisi, 1(1), 40-44.
  • Alayunt, N.Ö., Karagözoglu, Y., Parlak, A.E. & Türkoglu, S. (2013). Determination of the antioxidant vitamin levels in fresh and dried bee pollens in Bingol’s flora. Asian J. Chem, 25, 6870–6872.
  • Arserim Uçar, D.K., Geçibesler, İ.H., Sudağıdan, M., Dursun, İ., Süzerer, V. & Solmaz, R. (2020). Bingöl propolis izolatlarının biyolojik aktivitesinin, lipofilik ve uçucu organik bileşenlerinin belirlenmesi. Türk Doğa ve Fen Dergisi, 2020 Ekim TDFD Özel Sayısı, 92-102.
  • Ateş, Y. & Yaşar, S. (2020). Chemical investigations on honey produced in Bingol and surroundings. Uludağ Arıcılık Dergisi, 20 (1), 72-80.
  • Bakoğlu, A., Kutlu, M. & Bengü, A. (2014). Bingöl ilinde arıların yoğun olarak konakladıkları alanlarda üretilen ballarda bulunan polenlerin tespiti. Türk Tarım ve Doğa Bilimleri Dergisi, 1 (3) , 348-353.
  • Ballantine, I.T., Khurshid, A. & Ahsan, M.M. (2015).The Qur‘an: basic teachings. Springer Netherlands Press, 27–260.
  • Bengü, A.Ş., Ayna, A., Özbolat, S., Tunç, A., Aykutoğlu, G., Çiftci, M. & Darendelioğlu, E. (2020). Content and antimicrobial activities of Bingol royal jelly. Türk Tarım ve Doğa Bilimleri Dergisi, 7 (2), 480-486.
  • Bengü, A.Ş. & Kutlu, M.A. (2020). Bingöl’den temin edilen ballarda icp-ms ile bazı temel ve toksik elementlerin analizi. Uludağ Arıcılık Dergisi, 20 (1), 1-12.
  • Bengü, A.Ş. & Kutlu, M.A. (2018). Bingöl’de üretilen ballarda bazı kalite kriterlerinin belirlenmesi. Türk Doğa ve Fen Dergisi, 7 (1), 7-10.
  • Bergman, A., Yanai, J., Weiss, J., Bell, D. & David, M.P. (1983). Acceleration of wound healing by topical application of honey: an animal model. Am J Surg, 145, 374–6.
  • Bogdanov, S. (2009). Honey composition. The honey book, 1-9.
  • Bonvehí, J.S., Torrentó, M.S. & Lorente, E.C. (2001). Evaluation of polyphenolic and flavonoid compounds in honey bee-collected pollen produced in Spain. Journal Agricultural Food Chemistry, 49(4), 1843-1853.
  • Campos, M.G.R., Bogdanov, S., Almeida-Muradian, L.B.D., Szczesna, T., Mancebo, Y., Frigerio, C. & Ferreira, F. (2008). Pollen composition and standardisation of analytical methods. Journal of Apicultural Research, 47(2), 154–161.
  • Capcarova, M., Kolesarova, A., Kalafova, A., Galik, B., Simko, M., Juracek, M. & Toman, R. (2013). The role of dietary bee pollen in antioxidant potential in rats. Eurasian J Vet Sci, 29, 133-7.
  • Cauich-Kumul, R. & Segura Campos, M.R. (2019). Bee propolis. Bioactive Compounds, 227–243.
  • Çakar, G., Saraç Sivrikaya, I., Karakaya, E. & Güller, A. (2022). Inhibition effect of different propolis extracts against fusarium solani in vitro. Avrupa Bilim ve Teknoloji Dergisi, (35), 82-88.
  • Çakır, Y. & Dervişoğlu, G. (2022). Antimicrobial effect of honeys collected in Bingol region. MAS Journal of Applied Sciences, 7(2), 537–544.
  • Da Silva, P.M., Gauche, C., Gonzaga, L.V., Oliveira Costa, A.C.O. & Fett, R. (2016). Honey: chemical composition, stability and authenticity, Food Chem, 196, 309-323.
  • Daoud, A., Malika, D., Bakari, S., Hfaiedh, N., Mnafgui, K., Kadri, A. & Gharsallah, N. (2015). Assessment ofpolyphenol composition, antioxidant and antimicrobial properties of various extracts of Date Palm Pollen (DPP) from two Tunisian cultivars. Arabian J. Chem, 12, 3075-3086.
  • Demirpolat, A. & Kılıç, Ö. (2019). Genç (Bingöl-Merkez) ilçesi ve çevresi florasında arıcılık açısından önemli bitkiler. Uluslararası Doğu Anadolu Fen Mühendislik ve Tasarım Dergisi, 1 (2), 135-141.
  • Denisow, B. & Denisow-Pietrzyk, M. (2016). Biological and therapeutic properties of bee pollen: A review. Journal of the Science of Food & Agriculture, 96(13), 4303.
  • Dumitru, C.D., Neacsu, I.A., Grumezescu, A.M. & Andronescu, E. (2022). Bee-derived products: chemical composition and applications in skin tissue engineering. Pharmaceutics, 14(4), 750.
  • Devequi-Nunes, D., Machado, B.A.S., Barreto, G.d.A.,…& Umsza-Guez, M.A. (2018). Chemical characterization and biological activity of six different extracts of propolis through conventional methods and supercritical extraction. PloS One, 13 (12, article e0207676).
  • Estevinho, L.M., Chambó, E.D., Pereira, A.P.R., Carvalho, C.A.L. & Toledo, V.A.A. (2016). Characterization ofLavandula spp. honey using multivariate techniques. PLoS ONE, 11.
  • Estevinho, L.M., Rodrigues, S., Pereira, A.P. & Féas, X. (2012). Portuguese bee pollen: palynological study, nutritionaland microbiological evaluation. Int. J. Food Sci. Technol, 47, 429-435.
  • Inci, H., Sogut, B., Sengul, T., Yucel, B., Kokten, K., Tunca, R.I., Ayasan, T., Bengu, A.S., Gul, A., Celik, S., Sengul, A.Y., Yılmaz, H.S., Kutlu, M.A. & Şahin, İ. (2022). Comparison of fatty acid properties of Bingol propolis. South African Journal of Animal Science, 52 (3), 392-399.
  • İzol, E., Enes, K. & Karahan, D. (2021). Investigation of some metals in honey samples produced in different regions of Turkey's Bingöl province by ICP-MS. Mellifera, 21(1), 1-17.
  • Karampour, N.S., Hemmati, A.A. & Malmir, A. (2017). The anxiolytic effect of bee pollen hydroalcoholic extract inmice. Natl. J. Physiol. Pharm. Pharmacol, 7(3), 301-305.
  • Karagözoğlu, Y., Parlak, A.E. & Alayunt, N.Ö. (2012). Bingöl yöresinden toplanan arı polenlerinin yağ asidi miktarlarının incelenmesi. Selçuk Tarım ve Gıda Bilimleri Dergisi, 26 (3), 36-41.
  • Kaya, B. & Yıldırım, A. (2020). Determination of the antioxidant, antimicrobial and anticancer properties of the honey phenolic extract of five different regions of Bingöl province. J Food Sci Technol, 58(6), 2420-30.
  • Kaya, B., Gül, A. & Kutlu, M.A. (2016). Bingöl İli genç ilçesi bal örneklerinin fenolik ekstrelerinin antikanser, antioksidan ve antibakteriyel aktivitelerinin belirlenmesi. Turkish Journal of Agricultural and Natural Science, 3, 64-73.
  • Kilic, O. & Kutlu, M.A. (2016). Contributions to Bingol flora and beekeeping.Middle East Journal of Science (MEJS), 2, 24-30.
  • Kilic, O. & Yıldırımlı, Ş. (2014b). New native and cultivated floristic records for the square in the flora of Turkey. Ot Sistematik Botanik Dergisi, 21, 47-68.
  • Komosinska–Vassev, K., Olczyk, P., Kaźmierczak, J., Mencner, L. & Olczyk, K. (2015). Bee pollen chemical composition and therapeutic application. Evid based Complement Alternat Med, 1–6.
  • Meo, S.A., Al-Asiri, S.A., Mahesar, A.L. & Ansari, M.J. (2017). Role of honey in modern medicine. Saudi J. Biol. Sci,. 24, 975–978.
  • Mohammed, M.E.A. (2020). Factors affecting the physicochemical properties and chemical composition of bee’s honey. Food Reviews International, 1-12.
  • Dashora N., Sodde, V., Bhagat, J.,Prabhu, K.S. & Lobo, R. (2011). Antitumor activity of dendrophthoe falcata against ehrlich ascites carcinoma in Swiss Albino Mice. Pharmaceutical Crops, 2, 1–7.
  • Nogueira, C., Iglesias, A., Feás, X. & Estevinho, L.M. (2012). Commercial bee pollen with different geographical origins: A comprehensive approach. Int. J. Mol. Sci, 13, 11173-87.
  • Polat, R., Esim, N., Ürüşan, Z., Caf, A., Ahıskalı, M. & Canlı, D. (2020). Solhan (Bingöl) florasının arıcılık açısından değerlendirilmesi. Türk Doğa ve Fen Dergisi, 2020 Ekim TDFD Özel Sayısı, 1-10.
  • Pellati, F., Orlandini, G., Pinetti, D. & Benvenuti, S. (2011). HPLC-DAD and HPLC-ESI-MS/MS methods for metabolite profiling of propolis extracts. Journal of Pharmaceutical and Biomedical Analysis, 55(5), 934-948.
  • Ramsay, E.I., Rao, S., Madathil, L., Hegde, S.K., Baliga-Rao, M.P., George, T. & Baliga, M.S. (2019). Honey in oral health and care: A mini review. J. Oral Biosci, 61, 32–36.
  • Rao, P.V., Krishnan, K.T., Salleh, N. & Gan, S.H. (2016). Biological and therapeutic effects of honey produced by honey bees and stingless bees: a comparative review. Rev Brasil Farmacognosia, 26, 657–664.
  • Reis, J.H.d.O, Barreto, G.d.A., Cerqueira, J.C.,…& Machado, B.A.S. (2019). Evaluation of the antioxidant profile and cytotoxic activity of red propolis extracts from different regions of northeastern Brazil obtained by conventional and ultrasound-assisted extraction. PloS One, 14 (7, article e0219063).
  • Reis, L.C.B., de Souza, C.O., da Silva, J.B.A., Martins, A.C., Nunes, I.L. & Druzian, J.I. (2015). Active biocomposites ofcassava starch: The effect of yerba mate extract andmango pulp as antioxidant additives on the propertiesand the stability of a packaged product. Food Bioprod. Process, 94, 382-391.
  • Samarghandian, S., Farkhondeh, T. & Samini, F. (2017) Honey and health: a review of recent clinical research. Pharmacognosy Res, 9(2), 121-127.
  • Sarıkahya, N.B., Gören, A.C., Okkalı, G.S., Çöven, F.O., Orman, B., Kırcı, D., Yücel, B., Kışla, D., Demirci, B., Altun, M., Önem, A.N. & Nalbantsoy, A. (2021). Chemical composition and biological activities of propolis samples from different geographical regions of Turkey. Phytochemistry Letters, 44, 129-136.
  • Schmidt, J. (1996). Bee products: chemical composition and application. bee products, properties, applications, and apitherapy, the conference on bee products section 2, proceedings of an international conference on bee products: properties. Applications and Apitherapy, 26-30.
  • Thakur, M. & Nanda, V. (2020). Composition and functionality of bee pollen: A review. Trends Food Sci. Technol, 98, 82–106.
  • Zabaiou, N., Fouache, A., Trousson, A., Baron, S., Zellagui, A., Lahouel, M. & Lobaccaro, J.A. (2017). Biological properties of propolis extracts: Something new from an ancient product. Chem. Phys. Lipids, 207, 214–222.

Bingöl ili ve yöresine ait arı ürünlerinin biyolojik aktiviteleri

Yıl 2022, Cilt: 1 Sayı: 3, 170 - 180, 23.12.2022

Yusuf Karagözoğlu , Tuğba Raika Kıran

Öz

Bal, propolis, arı poleni, arı sütü, arı ekmeği, arı zehri ve balmumu arılar tarafından üretilen ürünlerdir. Bal, arı kovanlarından toplanan ve bal arısı peteklerinin hücrelerinde bulunan tatlı viskoz bir salgıdır. Propolis, arıların bitkilerin yapraklarından ve tomurcuklarından topladığı reçineli bir maddedir. Arı poleni, Apis mellifera L. bal arısının nektar ve arı salgılarıyla topladığı çiçek poleni karışımıdır. Antimikrobiyal, antiinflamatuar, antikanser ve antioksidan aktiviteler gibi çeşitli biyolojik özellikleri olan arı ürünleri, sağlık açısından önemli ve besin değeri yüksek doğal ürünlerdir.
Bingöl sahip olduğu bitki örtüsü ve coğrafi koşullar bakımından arıcılık potansiyeline oldukça elverişli bir bölgedir. Arıların en çok tercih ettikleri Fabaceae familyasından olan geven, üçgül ve fiğ bitkileri Bingöl florasında yetişmektedir. Ayrıca Asteraceae, Lamiaceae bu bölgede en fazla nektar toplanan diğer familya gruplarındandır. Çalışmada Bingöl’ün farklı lokasyonlarından elde edilen bal, arı poleni ve propolis örneklerindeki kimyasal parametreler, vitamin, yağ asidi, element içeriği, antioksidan, antimikrobiyal ve antikanser aktivite üzerine lokasyon farkı ve bitki türünün etkisi değerlendirilmiştir.       

Anahtar Kelimeler

Arı Ürünleri Bingöl Antioksidan Antimikrobiyal Antikanser

Kaynakça

  • Akkol, E.K., Orhan, D.D., Gürbüz, I. & Yesilada, E. (2010). In vivo activity assessment of a “honey-bee pollen mix” formulation, Pharmaceutical Biology, 48(3), 253-259.
  • Aksoy, Z. & Dığrak M. (2006). Bingöl yöresinde toplanan bal ve propolisin antimikrobiyal etkisi üzerinde in-vitro araştırmalar. Fırat Üniversitesi Fen ve Mühendislik Fakültesi Dergisi, 18(4), 471-478.
  • Alayunt, N.Ö., Karagözoğlu, Y. & Kutlu, M.A. (2012). Bingöl’den toplanan arı polenlerinde malondialdehid düzeylerinin iki farklı yöntemle belirlenmesi. Bitlis Eren Üniversitesi Fen Bilimleri Dergisi, 1(1), 40-44.
  • Alayunt, N.Ö., Karagözoglu, Y., Parlak, A.E. & Türkoglu, S. (2013). Determination of the antioxidant vitamin levels in fresh and dried bee pollens in Bingol’s flora. Asian J. Chem, 25, 6870–6872.
  • Arserim Uçar, D.K., Geçibesler, İ.H., Sudağıdan, M., Dursun, İ., Süzerer, V. & Solmaz, R. (2020). Bingöl propolis izolatlarının biyolojik aktivitesinin, lipofilik ve uçucu organik bileşenlerinin belirlenmesi. Türk Doğa ve Fen Dergisi, 2020 Ekim TDFD Özel Sayısı, 92-102.
  • Ateş, Y. & Yaşar, S. (2020). Chemical investigations on honey produced in Bingol and surroundings. Uludağ Arıcılık Dergisi, 20 (1), 72-80.
  • Bakoğlu, A., Kutlu, M. & Bengü, A. (2014). Bingöl ilinde arıların yoğun olarak konakladıkları alanlarda üretilen ballarda bulunan polenlerin tespiti. Türk Tarım ve Doğa Bilimleri Dergisi, 1 (3) , 348-353.
  • Ballantine, I.T., Khurshid, A. & Ahsan, M.M. (2015).The Qur‘an: basic teachings. Springer Netherlands Press, 27–260.
  • Bengü, A.Ş., Ayna, A., Özbolat, S., Tunç, A., Aykutoğlu, G., Çiftci, M. & Darendelioğlu, E. (2020). Content and antimicrobial activities of Bingol royal jelly. Türk Tarım ve Doğa Bilimleri Dergisi, 7 (2), 480-486.
  • Bengü, A.Ş. & Kutlu, M.A. (2020). Bingöl’den temin edilen ballarda icp-ms ile bazı temel ve toksik elementlerin analizi. Uludağ Arıcılık Dergisi, 20 (1), 1-12.
  • Bengü, A.Ş. & Kutlu, M.A. (2018). Bingöl’de üretilen ballarda bazı kalite kriterlerinin belirlenmesi. Türk Doğa ve Fen Dergisi, 7 (1), 7-10.
  • Bergman, A., Yanai, J., Weiss, J., Bell, D. & David, M.P. (1983). Acceleration of wound healing by topical application of honey: an animal model. Am J Surg, 145, 374–6.
  • Bogdanov, S. (2009). Honey composition. The honey book, 1-9.
  • Bonvehí, J.S., Torrentó, M.S. & Lorente, E.C. (2001). Evaluation of polyphenolic and flavonoid compounds in honey bee-collected pollen produced in Spain. Journal Agricultural Food Chemistry, 49(4), 1843-1853.
  • Campos, M.G.R., Bogdanov, S., Almeida-Muradian, L.B.D., Szczesna, T., Mancebo, Y., Frigerio, C. & Ferreira, F. (2008). Pollen composition and standardisation of analytical methods. Journal of Apicultural Research, 47(2), 154–161.
  • Capcarova, M., Kolesarova, A., Kalafova, A., Galik, B., Simko, M., Juracek, M. & Toman, R. (2013). The role of dietary bee pollen in antioxidant potential in rats. Eurasian J Vet Sci, 29, 133-7.
  • Cauich-Kumul, R. & Segura Campos, M.R. (2019). Bee propolis. Bioactive Compounds, 227–243.
  • Çakar, G., Saraç Sivrikaya, I., Karakaya, E. & Güller, A. (2022). Inhibition effect of different propolis extracts against fusarium solani in vitro. Avrupa Bilim ve Teknoloji Dergisi, (35), 82-88.
  • Çakır, Y. & Dervişoğlu, G. (2022). Antimicrobial effect of honeys collected in Bingol region. MAS Journal of Applied Sciences, 7(2), 537–544.
  • Da Silva, P.M., Gauche, C., Gonzaga, L.V., Oliveira Costa, A.C.O. & Fett, R. (2016). Honey: chemical composition, stability and authenticity, Food Chem, 196, 309-323.
  • Daoud, A., Malika, D., Bakari, S., Hfaiedh, N., Mnafgui, K., Kadri, A. & Gharsallah, N. (2015). Assessment ofpolyphenol composition, antioxidant and antimicrobial properties of various extracts of Date Palm Pollen (DPP) from two Tunisian cultivars. Arabian J. Chem, 12, 3075-3086.
  • Demirpolat, A. & Kılıç, Ö. (2019). Genç (Bingöl-Merkez) ilçesi ve çevresi florasında arıcılık açısından önemli bitkiler. Uluslararası Doğu Anadolu Fen Mühendislik ve Tasarım Dergisi, 1 (2), 135-141.
  • Denisow, B. & Denisow-Pietrzyk, M. (2016). Biological and therapeutic properties of bee pollen: A review. Journal of the Science of Food & Agriculture, 96(13), 4303.
  • Dumitru, C.D., Neacsu, I.A., Grumezescu, A.M. & Andronescu, E. (2022). Bee-derived products: chemical composition and applications in skin tissue engineering. Pharmaceutics, 14(4), 750.
  • Devequi-Nunes, D., Machado, B.A.S., Barreto, G.d.A.,…& Umsza-Guez, M.A. (2018). Chemical characterization and biological activity of six different extracts of propolis through conventional methods and supercritical extraction. PloS One, 13 (12, article e0207676).
  • Estevinho, L.M., Chambó, E.D., Pereira, A.P.R., Carvalho, C.A.L. & Toledo, V.A.A. (2016). Characterization ofLavandula spp. honey using multivariate techniques. PLoS ONE, 11.
  • Estevinho, L.M., Rodrigues, S., Pereira, A.P. & Féas, X. (2012). Portuguese bee pollen: palynological study, nutritionaland microbiological evaluation. Int. J. Food Sci. Technol, 47, 429-435.
  • Inci, H., Sogut, B., Sengul, T., Yucel, B., Kokten, K., Tunca, R.I., Ayasan, T., Bengu, A.S., Gul, A., Celik, S., Sengul, A.Y., Yılmaz, H.S., Kutlu, M.A. & Şahin, İ. (2022). Comparison of fatty acid properties of Bingol propolis. South African Journal of Animal Science, 52 (3), 392-399.
  • İzol, E., Enes, K. & Karahan, D. (2021). Investigation of some metals in honey samples produced in different regions of Turkey's Bingöl province by ICP-MS. Mellifera, 21(1), 1-17.
  • Karampour, N.S., Hemmati, A.A. & Malmir, A. (2017). The anxiolytic effect of bee pollen hydroalcoholic extract inmice. Natl. J. Physiol. Pharm. Pharmacol, 7(3), 301-305.
  • Karagözoğlu, Y., Parlak, A.E. & Alayunt, N.Ö. (2012). Bingöl yöresinden toplanan arı polenlerinin yağ asidi miktarlarının incelenmesi. Selçuk Tarım ve Gıda Bilimleri Dergisi, 26 (3), 36-41.
  • Kaya, B. & Yıldırım, A. (2020). Determination of the antioxidant, antimicrobial and anticancer properties of the honey phenolic extract of five different regions of Bingöl province. J Food Sci Technol, 58(6), 2420-30.
  • Kaya, B., Gül, A. & Kutlu, M.A. (2016). Bingöl İli genç ilçesi bal örneklerinin fenolik ekstrelerinin antikanser, antioksidan ve antibakteriyel aktivitelerinin belirlenmesi. Turkish Journal of Agricultural and Natural Science, 3, 64-73.
  • Kilic, O. & Kutlu, M.A. (2016). Contributions to Bingol flora and beekeeping.Middle East Journal of Science (MEJS), 2, 24-30.
  • Kilic, O. & Yıldırımlı, Ş. (2014b). New native and cultivated floristic records for the square in the flora of Turkey. Ot Sistematik Botanik Dergisi, 21, 47-68.
  • Komosinska–Vassev, K., Olczyk, P., Kaźmierczak, J., Mencner, L. & Olczyk, K. (2015). Bee pollen chemical composition and therapeutic application. Evid based Complement Alternat Med, 1–6.
  • Meo, S.A., Al-Asiri, S.A., Mahesar, A.L. & Ansari, M.J. (2017). Role of honey in modern medicine. Saudi J. Biol. Sci,. 24, 975–978.
  • Mohammed, M.E.A. (2020). Factors affecting the physicochemical properties and chemical composition of bee’s honey. Food Reviews International, 1-12.
  • Dashora N., Sodde, V., Bhagat, J.,Prabhu, K.S. & Lobo, R. (2011). Antitumor activity of dendrophthoe falcata against ehrlich ascites carcinoma in Swiss Albino Mice. Pharmaceutical Crops, 2, 1–7.
  • Nogueira, C., Iglesias, A., Feás, X. & Estevinho, L.M. (2012). Commercial bee pollen with different geographical origins: A comprehensive approach. Int. J. Mol. Sci, 13, 11173-87.
  • Polat, R., Esim, N., Ürüşan, Z., Caf, A., Ahıskalı, M. & Canlı, D. (2020). Solhan (Bingöl) florasının arıcılık açısından değerlendirilmesi. Türk Doğa ve Fen Dergisi, 2020 Ekim TDFD Özel Sayısı, 1-10.
  • Pellati, F., Orlandini, G., Pinetti, D. & Benvenuti, S. (2011). HPLC-DAD and HPLC-ESI-MS/MS methods for metabolite profiling of propolis extracts. Journal of Pharmaceutical and Biomedical Analysis, 55(5), 934-948.
  • Ramsay, E.I., Rao, S., Madathil, L., Hegde, S.K., Baliga-Rao, M.P., George, T. & Baliga, M.S. (2019). Honey in oral health and care: A mini review. J. Oral Biosci, 61, 32–36.
  • Rao, P.V., Krishnan, K.T., Salleh, N. & Gan, S.H. (2016). Biological and therapeutic effects of honey produced by honey bees and stingless bees: a comparative review. Rev Brasil Farmacognosia, 26, 657–664.
  • Reis, J.H.d.O, Barreto, G.d.A., Cerqueira, J.C.,…& Machado, B.A.S. (2019). Evaluation of the antioxidant profile and cytotoxic activity of red propolis extracts from different regions of northeastern Brazil obtained by conventional and ultrasound-assisted extraction. PloS One, 14 (7, article e0219063).
  • Reis, L.C.B., de Souza, C.O., da Silva, J.B.A., Martins, A.C., Nunes, I.L. & Druzian, J.I. (2015). Active biocomposites ofcassava starch: The effect of yerba mate extract andmango pulp as antioxidant additives on the propertiesand the stability of a packaged product. Food Bioprod. Process, 94, 382-391.
  • Samarghandian, S., Farkhondeh, T. & Samini, F. (2017) Honey and health: a review of recent clinical research. Pharmacognosy Res, 9(2), 121-127.
  • Sarıkahya, N.B., Gören, A.C., Okkalı, G.S., Çöven, F.O., Orman, B., Kırcı, D., Yücel, B., Kışla, D., Demirci, B., Altun, M., Önem, A.N. & Nalbantsoy, A. (2021). Chemical composition and biological activities of propolis samples from different geographical regions of Turkey. Phytochemistry Letters, 44, 129-136.
  • Schmidt, J. (1996). Bee products: chemical composition and application. bee products, properties, applications, and apitherapy, the conference on bee products section 2, proceedings of an international conference on bee products: properties. Applications and Apitherapy, 26-30.
  • Thakur, M. & Nanda, V. (2020). Composition and functionality of bee pollen: A review. Trends Food Sci. Technol, 98, 82–106.
  • Zabaiou, N., Fouache, A., Trousson, A., Baron, S., Zellagui, A., Lahouel, M. & Lobaccaro, J.A. (2017). Biological properties of propolis extracts: Something new from an ancient product. Chem. Phys. Lipids, 207, 214–222.
Toplam 51 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Klinik Tıp Bilimleri
Bölüm Derlemeler
Yazarlar

Yusuf Karagözoğlu 0000-0003-4201-0904

Tuğba Raika Kıran 0000-0002-3724-0249

Yayımlanma Tarihi 23 Aralık 2022
Gönderilme Tarihi 7 Ekim 2022
Yayımlandığı Sayı Yıl 2022 Cilt: 1 Sayı: 3

Kaynak Göster

APA Karagözoğlu, Y., & Kıran, T. R. (2022). Bingöl ili ve yöresine ait arı ürünlerinin biyolojik aktiviteleri. Journal of Medical Topics and Updates, 1(3), 170-180.
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