Comparison of intravenous lidocaine and intravenous lidocaine/paracetamol in prevention of postoperative sore throat after laryngeal mask insertion

Yıl 2020, , 1023 - 1026, 01.11.2020

Şule Arıcan , Resul Yılmaz , Gülçin Hacıbeyoğlu , Ayşegül Bilge , Rabia Yaman , Ahmet Topal , Sema Tuncer

https://doi.org/10.28982/josam.800727

Öz

Aim: Postoperative sore throat after general anesthesia with laryngeal mask airway is a common and undesirable complication. There are many agents and methods to prevent this complication. However, there is no study comparing intravenous lidocaine and lidocaine-paracetamol combination in the literature. The objective of this study was to compare the effects of systemic lidocaine and systemic lidocaine-paracetamol combination on postoperative sore throat in patients who underwent general anesthesia with laryngeal mask airway.
Methods: A total of 80 patients aged over 18 years with ASA I-III who underwent elective inguinal hernia surgery under general anesthesia with laryngeal mask airway were included in this cross-sectional study. Group LidoPara was administered 1 mg kg-1 lidocaine + 10 mg kg-1 paracetamol, and Group Lido, 1 mg kg-1 lidocaine. Resting and swallowing sore throat and hoarseness were evaluated with a 4-point scale at the postoperative 0th, 2nd, 4th, and 24th hours.
Results: Demographic data of the patients were similar (P>0.05). There was no statistically significant difference between the two groups in terms of resting and swallowing sore throat at the postoperative 0th, 2nd, 4th, and 24th hours. No hoarseness was found in both groups at the postoperative 4th and 24th hours.
Conclusion: Combined paracetamol and lidocaine was found to affect postoperative resting and swallowing sore throat similar to lidocaine alone.

Anahtar Kelimeler

general anesthesia, laryngeal mask airway, lidocaine, paracetamol, sore throat

Laringeal maske yerleşim sonrası postoperatif boğaz ağrısı sıklığının önlenmesinde intravenöz lidokain ve intravenöz lidokain/parasetamol kombinasyonunun karşılaştırılması

Öz

Amaç: Laringeal maske airway ile genel anestezi sonrası postoperatif boğaz ağrısı sık görülen ve istenmeyen bir komplikasyondur. Bu komplikasyonu önlemek için literatürde pekçok ajan ve metod vardır. Fakat lidokain ve lidokain-parasetamol kombinasyonunu karşılaştıran bir çalışma yoktur. Bu çalışmanın amacı laringeal maske airway ile genel anestezi uygulanan hastalarda, sistemik lidokain ile sistemik lidokain-parasetamol kombinasyonunun postoperatif boğaz ağrısı üzerine etkilerini karşılaştırmaktır.
Yöntemler: Kesitsel çalışmaya laringeal maske airway ile genel anestezi altında elektif inguinal herni cerrahisi olan, 18 yaşından büyük ASA fiziksel statüsü I-III olan 80 hasta dahil edildi. LidoPara grubuna 1mg/kg lidokain+10 mg/kg parasetamol, Lido grubuna 1mg/kg Lidokain uygulandı. Postoperatif 0, 2, 4 ve 24. saatlerde istirahat ve yutma boğaz ağrısı ve ses kısıklığı 4 puanlı bir skala ile değerlendirildi.
Bulgular: Hastaların demografik verileri benzerdi (P>0.05). İki grup arasında postoperatif 0, 2, 4 ve 24. saatlerde istirahat ve yutma boğaz ağrısı yönünden istatistiksel olarak anlamlı farklılık yoktu. Postoperatif 4. ve 24. saatte her iki grupta da ses kısıklığı yoktu.
Sonuç: Kombine parasetamol ve lidokainin postoperatif istirahat ve yutma esnasındaki boğaz ağrısını tek başına lidokain ile benzer şekilde etkilediği görüldü.

Anahtar Kelimeler

Genel anestezi, Laryngeal maske airway, Lidokain, Parasetamol, Boğaz ağrısı

Kaynakça

• 1. El-Boghdadly K, Bailey CR, Wiles MD. Postoperative sore throat: A systematic review. Anesthesia. 2016;71:706-17.
• 2. Dorsch JA, Dorsch SE. Supraglottic Airway devices. In: Dorsch JA, Dorsch SE, editors. Understanding Anaesthesia Equipment. 5th ed. Philadelphia: Lippincott Williams and Wilkins. 2008:461-519.
• 3. Jaensson M, Gupta A, Nilsson UG. Risk factors for development of postoperative sore throat and hoarseness after endotracheal intubation in women: A secondary analysis. AANA Journal. 2012;80:67-73.
• 4. Jaensson M, Olowsson LL, Nilsson U. Endotracheal tube size and sore throat following surgery: a randomized-controlled study. Acta Anaesthesiol Scand. 2010;54:147-53.
• 5. Tanaka Y, Nakayama T, Nishimori M, Tsujimura Y, Kawaguchi M, Sato Y. Lidocaine for preventing postoperative sore throat. Cochrane Database Syst Rev. 2015;7:Cd004081.
• 6. Duggan ST, Scott LJ. Intravenous paracetamol (acetaminophen). Drugs. 2009;69: 101–13.
• 7. Jebaraj B, Maitra S, Baidya DK, Khanna P. Intravenous paracetamol reduces postoperative opioid consumption after orthopedic surgery: a systematic review of clinical trials. Pain Res Treat. 2013:402510.
• 8. Olonisakin RP, Amanor-Boadu SD, Akinyemi AO. Morphine sparing effect of intravenous paracetamol for post operative pain management following gynaecological surgery. Afr J Med Med Sci. 2012;41:429–36.
• 9. Gehling M, Arndt C, Eberhart LH, Koch T, Krüger T, Wulf H. Postoperative analgesia with parecoxib, acetaminophen, and the combination of both: a randomized, double-blind, placebo-controlled trial in patients undergoing thyroid surgery. Br J Anaesth. 2010;104:761–7.
• 10. Wong DT, Tam AD, Mehta V, Raveendran R, Riad W, Chung FF. New supraglottic airway with built-in pressure indicator decreases postoperative pharyngolaryngeal symptoms: a randomized controlled trial. Can J Anaesth. 2013;60:1197.
• 11. Hermite JL, Dubout E, Bouvet S, Bracoud LH, Cuvillon P, Coussaye JE et al. Sore throat following three adult supraglottic airway devices: A randomised controlled trial. Eur J Anaesthesiol. 2017;34:417-24.
• 12. Ebneshahidi A, Mohseni M. Strepsils tablets reduce sore throat and hoarseness after tracheal intubation. Anesth Analg 2010;111:892–4.
• 13. Aydın GB, Ergil J, Polat R, Sayın M, Akelma FK. Comparison of Siccoral spray, Stomatovis gargle, and Strefen lozenges on postoperative sore throat. J Anesth. 2014;28:494–8
• 14. Rasmussen ML, Mathiesen O, Dierking G, Christensen BV, Hilsted KL, Larsen TK, et al. Multimodal analgesia with gabapentin, ketamine and dexamethasone in combination with paracetamol and ketorolac after hip arthroplasty: a preliminary study. Eur J Anaesthesiol. 2010;27:324–30.
• 15. Hollmann MW, Durieux ME. Local anesthetics and the inflammatory response: a new therapeutic indication?. Anesthesiology. 2000;93:858–75.
• 16. Takekawa K, Yoshimi S, Kinoshita Y. Effects of intravenous lidocaine prior to intubation on postoperative airway symptoms. J Anesth. 2006;20:44–7.
• 17. Kumar A, Seth A, Prakash S, Deganwa M, Gogia AR. Attenuation of the hemodynamic response to laryngoscopy and tracheal intubation with fentanyl, lignocaine nebulization, and a combination of both:A randomized controlled trial. Anesth Essays Res. 2016;10:661– 6.
• 18. Thomas M, Del Mar C, Glasziou P. How effective are treatments other than antibiotics for acute sore throat?. Br J Gen Pract. 2000;50:817–20
• 19. Mathiesen O, Rasmussen ML, Dierking G, Lech K, Hilsted KL, Fomsgaard JS, et al.. Pregabalin and dexamethasone in combination with paracetamol for postoperative pain control after abdominal hysterectomy. A randomized clinical trial. Acta Anaesthesiol Scand. 2009;53:227–35.
• 20. Ohnesorge H, Bein B, Hanss R, Francksen H, Mayer L, Scholz J, et al. Paracetamol versus metamizol in the treatment of postoperative pain after breast surgery: a randomized, controlled trial. Eur J Anaesthesiol. 2009;26:648–53.
• 21. Lee J, Park HP, Jeong MH, Kim HC. Combined intraoperative paracetamol and preoperative dexamethasone reduces postoperative sore throat: a prospective randomized study. J Anesth. 2017;31:869-77.
• 22. Christensen AM, Willemoes-Larsen H, Lundby L, Jakobsen KB. Postoperative throat complaints after tracheal intubation. Br J Anaesth. 1994;73:786–7.
• 23. Canbay O, Celebi N, Sahin A, Celiker V, Ozgen S, Aypar U. Ketamine gargle for attenuating postoperative sore throat. Br J Anaesth. 2008;100:490–3.
• 24. Seet E, Yousaf F, Gupta S, Subramanyam R, Wong DT, Chung F. Use of manometry for laryngeal mask airway reduces postoperative pharyngolaryngeal adverse events: a prospective, randomized trial. Anesthesiology 2010;112:652.