SAĞLIK ALANINDA SANAL GERÇEKLİK UYGULAMALARI

Öz

Sanal gerçeklik, bilgisayar tarafından oluşturulan simüle edilmiş bir ortama, kullanıcıları taşıyan teknoloji ve deneyim türüdür. Kullanıcıyı gerçek dünyadan soyutlayarak bilgisayar ile oluşturulmuş ortamda duyusal bir deneyim sunmaktadır. Sanal gerçeklik eğlence, eğitim, sağlık, askeri, mühendislik ve birçok farklı endüstrinin çeşitli alanlarında kullanılmaktadır. Sanal gerçeklik uygulamaları sağlık alanında sürekli olarak gelişen bir teknoloji olup, kullanım alanları genişlemeye devam etmektedir. Sağlık alanında terapi ve rehabilitasyon, cerrahi planlama ve eğitim, hastaneye yatış, ağrı yönetimi, kemoterapi alan kanserli hastalara destek, yeme bozuklukları, eğitim ve simülasyon, anksiyete bozukluklarının tedavisi, diş hekimliği klinik uygulamaları gibi birçok farklı uygulama ve kullanım alanına sahiptir. Sanal gerçeklik simülasyonları, yeni becerilerin öğrenilmesi ve mevcut yeteneklerin güncellenmesi için etkili bir araçtır; aynı zamanda hastaların tedavi süreçlerinde duygusal faktörleri, özellikle endişe ve korku gibi duygusal zorlukları hafifletmede yardımcı olmaktadır. Sanal gerçeklik kullanılarak hastalar için sakinleştirici bir atmosfer oluşturulabilir ve tedaviye olan uyumlarını arttırılabilir. Ayrıca, görsel ve işitsel simülasyonlar aracılığıyla ağrıyı azaltabilir, bu da tedavi sürecini daha hoş bir deneyime dönüştürebilir. Bu teknoloji, hastalara daha etkili ve kişiselleştirilmiş bir tedavi sağlama potansiyeli taşımaktadır. Bu derlemede, sağlık alanında kullanılabilen sanal gerçeklik uygulamalarını sunmak amaçlanmaktadır.

Anahtar Kelimeler

• Dental Tedavilerde Sanal Gerçeklik
• Rehabilitasyonda Sanal Gerçeklik
• Sağlık Alanında Sanal Gerçeklik
• Sanal Gerçeklik Uygulamaları

Virtual Reality Applications in Healthcare

Öz

Virtual reality is a type of technology and experience that immerses users in a computer-generated simulated environment. By isolating users from the real world, it provides a sensory experience within a digitally created setting. Virtual reality is utilized across various industries, including entertainment, education, healthcare, military, and engineering, among many others. In the healthcare sector, virtual reality applications are continuously evolving, with an expanding range of uses. It plays a significant role in areas such as therapy and rehabilitation, surgical planning and training, hospitalization, pain management, support for cancer patients undergoing chemotherapy, eating disorders, education and simulation, treatment of anxiety disorders, and clinical applications in dentistry. Virtual reality simulations serve as an effective tool for acquiring new skills and updating existing ones. Additionally, they help alleviate emotional challenges in patients, such as anxiety and fear, during treatment processes. By using virtual reality, a calming atmosphere can be created for patients, enhancing their compliance with treatment. Moreover, visual and auditory simulations can reduce pain, making the treatment process a more pleasant experience. This technology holds great potential for providing patients with more effective and personalized treatment. This review aims to present various virtual reality applications used in the healthcare field.

Anahtar Kelimeler

• Virtual Reality Applications
• Virtual Reality in Dental Treatment
• Virtual Reality in Healthcare
• Virtual Reality in Rehabilitation

Kaynakça

1. Al-Namankany, A., Petrie, A., & Ashley, P. (2014). Video modelling and reducing anxiety related to dental injections a randomised clinical trial. Br Dent J, 216(12), 675–679. https://doi.org/10.1038/sj.bdj.2014.497
2. Arikatla, V. S., Tyagi, M., Enquobahrie, A., Nguyen, T., Blakey, G. H., White, R., & Paniagua, B. (2018). High Fidelity Virtual Reality Orthognathic Surgery Simulator. Proc SPIE Int Soc Opt Eng, 10576, 1057612. https://doi.org/10.1117/12.2293690
3. Baños, R. M., Espinoza, M., García-Palacios, A., Cervera, J. M., Esquerdo, G., Barrajón, E., & Botella, C. (2013). A positive psychological intervention using virtual reality for patients with advanced cancer in a hospital setting: a pilot study to assess feasibility. Support Care Cancer, 21(1), 263–270. https://doi.org/10.1007/s00520-012-1520-x
4. Bantick, S. J., Wise, R. G., Ploghaus, A., Clare, S., Smith, S. M., & Tracey, I. (2002). Imaging how attention modulates pain in humans using functional MRI. Brain, 125(Pt 2), 310–319. https://doi.org/10.1093/brain/awf022
5. Barbato, S., Di Natale, L. (2017), Finestre sul Futuro; Alpes: Roma, Italy.
6. Bekelis, K., Calnan, D., Simmons, N., MacKenzie, T. A., & Kakoulides, G. (2017). Effect of an Immersive Preoperative Virtual Reality Experience on Patient Reported Outcomes: A Randomized Controlled Trial. Ann Surg, 265(6), 1068–1073. https://doi.org/10.1097/SLA.0000000000002094
7. Buchanan J. A. (2004). Experience with virtual reality-based technology in teaching restorative dental procedures. J Dent Educ, 68(12), 1258–1265. https://doi.org/10.1002/j.0022-0337.2004.68.12.tb03875.x
8. Burdea G. C. (2003). Virtual rehabilitation-benefits and challenges. Methods Inf Med, 42(5), 519–523. https://doi.org/10.1055/s-0038-1638156

9. Carrougher, G. J., Hoffman, H. G., Nakamura, D., Lezotte, D., Soltani, M., Leahy, . . . Patterson, D. R. (2009). The effect of virtual reality on pain and range of motion in adults with burn injuries. J Burn Care Res, 30(5), 785–791. https://doi.org/10.1097/BCR.0b013e3181b485d3 Chaddad, A., Jiang, Y. (2025). Integrating technologies in the metaverse for enhanced healthcare and medical education. IEEE Trans Learn Technol, PP(99):1-14 doi:10.1109/TLT.2025.3537802.
10. Chirico, A., Lucidi, F., De Laurentiis, M., Milanese, C., Napoli, A., & Giordano, A. (2016). Virtual Reality in Health System: Beyond Entertainment. A Mini-Review on the Efficacy of VR During Cancer Treatment. J Cell Physiol, 231(2), 275–287. https://doi.org/10.1002/jcp.25117
11. Cunningham, A., McPolin, O., Fallis, R., Coyle, C., Best, P., & McKenna, G. (2021). A systematic review of the use of virtual reality or dental smartphone applications as interventions for management of paediatric dental anxiety. BMC Oral Health, 21(1), 244. https://doi.org/10.1186/s12903-021-01602-3
12. Dockx, K., Bekkers, E. M., Van den Bergh, V., Ginis, P., Rochester, L., Hausdorff, J. M., … Nieuwboer, A. (2016). Virtual reality for rehabilitation in Parkinson's disease. Cochrane Database Syst Rev, 12(12), CD010760. https://doi.org/10.1002/14651858.CD010760.pub2
13. Doğaner, YÇ., Aydoğan, Ü., Yeşil, H., Sarı, O., Koç, B. (2015). Genç bireylerde dental anksiyete ve ilişkili faktörler. Gulhane Med J, 57(2), 160-164. https://doi.org/10.33631/sabd.1338778
14. Elkefi, S., Choudhury, A. (2025). Role of Virtual Reality in Improving Home Cancer Care: A Systematic Literature Review. Electronics, 14(2), 385. https://doi.org/10.3390/electronics14020385
15. Ershow, A. G., Peterson, C. M., Riley, W. T., Rizzo, A. S., & Wansink, B. (2011). Virtual reality technologies for research and education in obesity and diabetes: research needs and opportunities. J Diabetes Sci Technol, 5(2), 212–224. https://doi.org/10.1177/193229681100500202
16. Espinoza, M., Baños, R. M., García-Palacios, A., Cervera, J. M., Esquerdo, G., Barrajón, E., & Botella, C. (2012). Promotion of emotional wellbeing in oncology inpatients using VR. Stud Health Technol Inform, 181, 53–57. https://doi.org/10.3233/978-1-61499-121-2-53
17. Fan, L., Zeng, J., Ran, L., Zhang, C., Wang, J., Yu, C., & Zhao, N. (2023). Virtual reality in managing dental pain and anxiety: a comprehensive review. Front Med, 10, 1285142. https://doi.org/10.3389/fmed.2023.1285142
18. Feltz, D. L., Kerr, N. L., & Irwin, B. C. (2011). Buddy up: the Köhler effect applied to health games. J Sport Exerc Psychol, 33(4), 506–526. https://doi.org/10.1123/jsep.33.4.506
19. Ferrer-Garcia, M., Pla-Sanjuanelo, J., Dakanalis, A., Vilalta-Abella, F., Riva, G., Fernandez-Aranda, . . . Gutiérrez-Maldonado, J. (2019). A Randomized Trial of Virtual Reality-Based Cue Exposure Second-Level Therapy and Cognitive Behavior Second-Level Therapy for Bulimia Nervosa and Binge-Eating Disorder: Outcome at Six-Month Followup. Cyberpsychol Behav Soc Netw, 22(1), 60–68. https://doi.org/10.1089/cyber.2017.0675
20. Fox, J., Bailenson, JN. (2009) Virtual self-modeling: the effects of vicarious reinforcement and identification on exercise behaviors. Media Psychol;12(1):1–25. https://doi.org/10.1080/15213260802669474
21. Galeazzi, A., di Milo, G. (2011) Nuove frontiere in psicoterapia: La realtà virtuale. Psicoter. Cogn. Comport, 17(1) 31–52.
22. Gallo, L., Minutolo, A., & De Pietro, G. (2010). A user interface for VR-ready 3D medical imaging by off-the-shelf input devices. Comput Biol Med, 40(3), 350–358. https://doi.org/10.1016/j.compbiomed.2010.01.006
23. Garrett, B., Taverner, T., Masinde, W., Gromala, D., Shaw, C., & Negraeff, M. (2014). A rapid evidence assessment of immersive virtual reality as an adjunct therapy in acute pain management in clinical practice. Clin J Pain, 30(12), 1089–1098. https://doi.org/10.1097/AJP.0000000000000064
24. Gershon, J., Zimand, E., Pickering, M., Rothbaum, B. O., & Hodges, L. (2004). A pilot and feasibility study of virtual reality as a distraction for children with cancer. J Am Acad Child Adolesc Psychiatry, 43(10), 1243–1249. https://doi.org/10.1097/01.chi.0000135621.23145.0546.
25. Goble, D. J., Cone, B. L., & Fling, B. W. (2014). Using the Wii Fit as a tool for balance assessment and neurorehabilitation: the first half decade of "Wii-search". J Neuroeng Rehabil, 11, 12. https://doi.org/10.1186/1743-0003-11-12
26. Gold, J. I., Belmont, K. A., & Thomas, D. A. (2007). The neurobiology of virtual reality pain attenuation. Cyberpsychol Behav, 10(4), 536–544. https://doi.org/10.1089/cpb.2007.9993
27. Gold, J. I., & Mahrer, N. E. (2018). Is Virtual Reality Ready for Prime Time in the Medical Space? A Randomized Control Trial of Pediatric Virtual Reality for Acute Procedural Pain Management. J Pediatr Psychol, 43(3), 266–275. https://doi.org/10.1093/jpepsy/jsx129 Gonçalves, R., Pedrozo, A. L., Coutinho, E. S., Figueira, I., & Ventura, P. (2012). Efficacy of virtual reality exposure therapy in the treatment of PTSD: a systematic review. PloS one, 7(12), e48469. https://doi.org/10.1371/journal.pone.0048469
28. Gramaglia, G. (2013), La Realtà Virtuale in Psicoterapia: Scienza o Fantascienza? Ilmiolibro Self Publishing. Milano: Italy.
29. Grassi, L., Berardi, M. A., Ruffilli, F., Meggiolaro, E., Andritsch, E., Sirgo, A., . . . Nanni, M. G., Psycho-Oncology and UniFE Psychiatry Co-Authors (2015). Role of psychosocial variables on chemotherapy-induced nausea and vomiting and health-related quality of life among cancer patients: a European study. Psychother Psychosom, 84(6), 339–347. https://doi.org/10.1159/000431256
30. Haythronthwaite, J. A., Lawrence, J. W., & Fauerbach, J. A. (2001). Brief cognitive interventions for burn pain. Ann Behav Med, 23(1), 42–49. https://doi.org/10.1207/S15324796ABM2301_7
31. Hilty, DM., Randhawa, K., Maheu, MM., McKean, AJS., Pantera, R., Mishkind, MC., Albert R. A review of telepresence, virtual reality and augmented reality applied to clinical care. J Technol Behav Sci. 2020; 5(1):1-28. https://doi.org/10.1007/s41347-020-00126-x
32. Hoffman, H. G., Chambers, G. T., Meyer, W. J., 3rd, Arceneaux, L. L., Russell, W. J., Seibel, . . . Patterson, D. R. (2011). Virtual reality as an adjunctive non-pharmacologic analgesic for acute burn pain during medical procedures. Ann Behav Med, 41(2), 183–191. https://doi.org/10.1007/s12160-010-9248-7
33. Hoffman, H. G., Doctor, J. N., Patterson, D. R., Carrougher, G. J., & Furness, T. A., 3rd (2000). Virtual reality as an adjunctive pain control during burn wound care in adolescent patients. Pain, 85(1-2), 305–309. https://doi.org/10.1016/s0304-3959(99)00275-4
34. Işıklı, S., Baran, Z., Aslan, S. (2019) Özgül fobilerde sanal gerçeklik teknolojisi uygulamaları ile tedaviye yardımcı araç geliştirme: Bir etkililik çalışması. Klinik Psikiyatri Dergisi, 22(3): 316-32. https://doi.org/10.5505/kpd.2019.43660
35. Jung, E. Y., Park, D. K., Lee, Y. H., Jo, H. S., Lim, Y. S., & Park, R. W. (2012). Evaluation of practical exercises using an intravenous simulator incorporating virtual reality and haptics device technologies. Nurse Educ Today, 32(4), 458–463. https://doi.org/10.1016/j.nedt.2011.05.012
36. Keshner E. A. (2004). Virtual reality and physical rehabilitation: a new toy or a new research and rehabilitation tool? J Neuroeng Rehabil, 1(1), 8. https://doi.org/10.1186/1743-0003-1-8
37. Khor, W. S., Baker, B., Amin, K., Chan, A., Patel, K., & Wong, J. (2016). Augmented and virtual reality in surgery-the digital surgical environment: applications, limitations and legal pitfalls. Ann Transl Med, 4(23), 454. https://doi.org/10.21037/atm.2016.12.23
38. Kipping, B., Rodger, S., Miller, K., & Kimble, R. M. (2012). Virtual reality for acute pain reduction in adolescents undergoing burn wound care: a prospective randomized controlled trial. Burns, 38(5), 650–657. https://doi.org/10.1016/j.burns.2011.11.010
39. Lewis, G. N., & Rosie, J. A. (2012). Virtual reality games for movement rehabilitation in neurological conditions: how do we meet the needs and expectations of the users?. Disabil Rehabil, 34(22), 1880–1886. https://doi.org/10.3109/09638288.2012.670036
40. Li, W. H., Chung, J. O., Ho, E. K., & Chiu, S. Y. (2011). Effectiveness and feasibility of using the computerized interactive virtual space in reducing depressive symptoms of Hong Kong Chinese children hospitalized with cancer. J Spec Pediatr Nurs, 16(3), 190–198. https://doi.org/10.1111/j.1744-6155.2011.00288.x
41. Lutgendorf, S. K., Sood, A. K., & Antoni, M. H. (2010). Host factors and cancer progression: biobehavioral signaling pathways and interventions. J Clin Oncol, 28(26), 4094–4099. https://doi.org/10.1200/JCO.2009.26.9357
42. Maples-Keller, J. L., Yasinski, C., Manjin, N., & Rothbaum, B. O. (2017). Virtual Reality-Enhanced Extinction of Phobias and Post-Traumatic Stress. Neurotherapeutics, 14(3), 554–563. https://doi.org/10.1007/s13311-017-0534-y
43. Meyerbröker, K., & Emmelkamp, P. M. (2010). Virtual reality exposure therapy in anxiety disorders: a systematic review of process-and-outcome studies. Depress Anxiety, 27(10), 933–944. https://doi.org/10.1002/da.20734
44. Mirelman, A., Maidan, I., & Deutsch, J. E. (2013). Virtual reality and motor imagery: promising tools for assessment and therapy in Parkinson's disease. Mov Disord, 28(11), 1597–1608. https://doi.org/10.1002/mds.25670
45. Moro, C., Štromberga, Z., Raikos, A., & Stirling, A. (2017). The effectiveness of virtual and augmented reality in health sciences and medical anatomy. Anat Sci Educ, 10(6), 549–559. https://doi.org/10.1002/ase.1696
46. Napolitano, M. A., Hayes, S., Russo, G., Muresu, D., Giordano, A., & Foster, G. D. (2013). Using avatars to model weight loss behaviors: participant attitudes and technology development. J Diabetes Sci Technol, 7(4),1057–1065. https://doi.org/10.1177/193229681300700430
47. Nilsson, S., Finnström, B., Kokinsky, E., & Enskär, K. (2009). The use of Virtual Reality for needle-related procedural pain and distress in children and adolescents in a paediatric oncology unit. Eur J Oncol Nurs, 13(2), 102–109. https://doi.org/10.1016/j.ejon.2009.01.003
48. Opriş, D., Pintea, S., García-Palacios, A., Botella, C., Szamosközi, Ş., & David, D. (2012). Virtual reality exposure therapy in anxiety disorders: a quantitative meta-analysis. Depress Anxiety, 29(2), 85–93. https://doi.org/10.1002/da.20910
49. Panda, A. (2017) Effect of virtual reality distraction on pain perception during dental treatment in children. Int J Oral Care Res, 5(10), 278-281. https://doi.org/10.5005/jp-journals-10051-0115
50. Persky S. (2011). Application of virtual reality methods to obesity prevention and management research. J Diabetes Sci Technol, 5(2), 333–339. https://doi.org/10.1177/193229681100500220
51. Piskorz, J., & Czub, M. (2018). Effectiveness of a virtual reality intervention to minimize pediatric stress and pain intensity during venipuncture. J Spec Pediatr Nurs: JSPN, 23(1), 10.1111/jspn.12201. https://doi.org/10.1111/jspn.12201
52. Powers, M. B., & Emmelkamp, P. M. (2008). Virtual reality exposure therapy for anxiety disorders: A meta-analysis. J Anxiety Disord, 22(3), 561–569. https://doi.org/10.1016/j.janxdis.2007.04.006
53. Prajapati, M. & Kumar, S. (2025). Virtual reality revolution in healthcare: a systematic review. Health Technol, 1-12. https://doi.org/10.1007/s12553-025-00941-3
54. Qin, Z., Zhou, C., Zhu, Y., Wang, Y., Cao, H., Li, W., & Huang, Z. (2022). Virtual Reality for Hypertension in Tooth Extraction: A Randomized Trial. J Dent Res, 101(4), 400–406. https://doi.org/10.1177/00220345211049393
55. Quinn, F., Keogh, P., McDonald, A., & Hussey, D. (2003). A pilot study comparing the effectiveness of conventional training and virtual reality simulation in the skills acquisition of junior dental students. Eur J Dent Educ, 7(1), 13–19. https://doi.org/10.1034/j.1600-0579.2003.00264.x
56. Raghav, K., Van Wijk, A. J., Abdullah, F., Islam, M. N., Bernatchez, M., & De Jongh, A. (2016). Efficacy of virtual reality exposure therapy for treatment of dental phobia: a randomized control trial. BMC Oral Health, 16, 25. https://doi.org/10.1186/s12903-016-0186-z
57. Rantamaa, H. R., Kangas, J., Jordan, M., Mehtonen, H., Mäkelä, J., Ronkainen, . . .Raisamo, R. (2022). Evaluation of virtual handles for dental implant manipulation in virtual reality implant planning procedure. Int J Comput Assist Radiol Surg, 17(9), 1723–1730. https://doi.org/10.1007/s11548-022-02693-1
58. Reyes-Acuca, M. J., Sánchez-Lezama, Z. S., Capistrán-Sarmiento, B., Teodoro-Isneros, A., Suárez-Franco, J. L., & Cerda-Cristerna, B. I. (2020). Learning of the mental nerve block technique with dental anaesthesia simulation models builds motor skills and confidence in dental students. Eur J Dent Educ, 24(3), 491–498. https://doi.org/10.1111/eje.12527
59. Reymus, M., Liebermann, A., & Diegritz, C. (2020). Virtual reality: an effective tool for teaching root canal anatomy to undergraduate dental students- a preliminary study. Int Endod J, 53(11), 1581–1587. https://doi.org/10.1111/iej.13380
60. Riki, GJ., Marjoke Vervoorn, JB. (2013) Simulation in dentistry and oral health. The comprehensive textbook of healthcare simulation. New York: NY Springer.
61. Riva, G., Melis, L., Bolzoni, M. (1997) Treating body image disturbances. Communications of the ACM; 40:69–71. https://doi.org/10.1089/cyber.2016.0012
62. Riva, G., Gaggioli, A. Realtà Virtuali. (2019), Gli Aspetti Psicologici Delle Tecnologie Simulative e il Loro Impatto Sull’esperienza Umana Giunti. Firenze: Italy.
63. Ryu, J. H., Park, S. J., Park, J. W., Kim, J. W., Yoo, H. J., Kim, . . .Han, S. H. (2017). Randomized clinical trial of immersive virtual reality tour of the operating theatre in children before anaesthesia. Br J Surg, 104(12), 1628–1633. https://doi.org/10.1002/bjs.10684
64. Scheffler, M., Koranyi, S., Meissner, W., Strauß, B., & Rosendahl, J. (2018). Efficacy of non-pharmacological interventions for procedural pain relief in adults undergoing burn wound care: A systematic review and meta-analysis of randomized controlled trials. Burns: Burns, 44(7), 1709–1720. https://doi.org/10.1016/j.burns.2017.11.019
65. Schneider, S. M., & Workman, M. L. (1999). Effects of virtual reality on symptom distress in children receiving chemotherapy. Cyberpsychol Behav, 2(2), 125–134. https://doi.org/10.1089/cpb.1999.2.125
66. Schneider, S. M., & Hood, L. E. (2007). Virtual reality: a distraction intervention for chemotherapy. Oncol Nurs Forum, 34(1), 39–46. https://doi.org/10.1188/07.ONF.39-46
67. Schneider, S. M., Kisby, C. K., & Flint, E. P. (2011). Effect of virtual reality on time perception in patients receiving chemotherapy. Support Care Cancer, 19(4), 555–564. https://doi.org/10.1007/s00520-010-0852-7
68. Schuster-Amft, C., Eng, K., Suica, Z., Thaler, I., Signer, S., Lehmann, . . . Kiper, D. (2018). Effect of a four-week virtual reality-based training versus conventional therapy on upper limb motor function after stroke: A multicenter parallel group randomized trial. PloS one, 13(10), e0204455. https://doi.org/10.1371/journal.pone.0204455
69. Scolozzi, P., & Bijlenga, P. (2017). Removal of recurrent intraorbital tumour using a system of augmented reality. Br J Oral Maxillofac Surg, 55(9), 962–964. https://doi.org/10.1016/j.bjoms.2017.08.360
70. Smith, JD., & Steel, J. (2000). The use of virtual simulation for dismounted infantry training. In Proceedings of the NATO Modelling & Simulation Conference, Shrivenham, UK.
71. Sullivan, C., Schneider, P. E., Musselman, R. J., Dummett, C. O., Jr, & Gardiner, D. (2000). The effect of virtual reality during dental treatment on child anxiety and behavior. ASDC J Dent Child, 67(3), 193–161. url={https://api.semanticscholar.org/CorpusID:23329663}
72. Summer, G. J., Puntillo, K. A., Miaskowski, C., Green, P. G., & Levine, J. D. (2007). Burn injury pain: the continuing challenge. J Pain, 8(7), 533–548. https://doi.org/10.1016/j.jpain.2007.02.426
73. Sveistrup, H. (2004). Motor rehabilitation using virtual reality. J Neuroeng Rehabil, 1(1), 10. https://doi.org/10.1186/1743-0003-1-10
74. Teo, W. P., Muthalib, M., Yamin, S., Hendy, A. M., Bramstedt, K., Kotsopoulos, E., … Ayaz, H. (2016). Does a Combination of Virtual Reality, Neuromodulation and Neuroimaging Provide a Comprehensive Platform for Neurorehabilitation? - A Narrative Review of the Literature. Front Hum Neurosci, 10, 284. https://doi.org/10.3389/fnhum.2016.00284
75. Van Twillert, B., Bremer, M., & Faber, A. W. (2007). Computer-generated virtual reality to control pain and anxiety in pediatric and adult burn patients during wound dressing changes. J Burn Care Res, 28(5), 694–702. https://doi.org/10.1097/BCR.0B013E318148C96F
76. Weiss, P. L., Rand, D., Katz, N., & Kizony, R. (2004). Video capture virtual reality as a flexible and effective rehabilitation tool. J Neuroeng Rehabil, 1(1), 12. https://doi.org/10.1186/1743-0003-1-12
77. Whiteford, H. A., Degenhardt, L., Rehm, J., Baxter, A. J., Ferrari, A. J., Erskine, H. E., . . . Vos, T. (2013). Global burden of disease attributable to mental and substance use disorders: findings from the Global Burden of Disease Study 2010. Lancet (London, England), 382(9904), 1575–1586. https://doi.org/10.1016/S0140-6736(13)61611-6
78. Wiechman Askay, S., & Patterson, D. R. (2008). What are the psychiatric sequelae of burn pain? Curr Pain Headache Rep, 12(2), 94–97. https://doi.org/10.1007/s11916-008-0018-1
79. Wiederhold, B. K., Riva, G., & Gutiérrez-Maldonado, J. (2016). Virtual Reality in the Assessment and Treatment of Weight-Related Disorders. Cyberpsychology Behav Soc Netw, 19(2), 67–73. https://doi.org/10.1089/cyber.2016.0012 Winkels, D. G., Kottink, A. I., Temmink, R. A., Nijlant, J. M., & Buurke, J. H. (2013). Wii™-habilitation of upper extremity function in children with cerebral palsy. An explorative study. Dev Neurorehabil, 16(1), 44–51. https://doi.org/10.3109/17518423.2012.713401
80. Wismeijer, A. A., & Vingerhoets, A. J. (2005). The use of virtual reality and audiovisual eyeglass systems as adjunct analgesic techniques: a review of the literature. Ann Behav Med, 30(3), 268–278. https://doi.org/10.1207/s15324796abm3003_11
81. Yeh, S. C., Lee, S. H., Chan, R. C., Chen, S., & Rizzo, A. (2014). A virtual reality system integrated with robot-assisted haptics to simulate pinch-grip task: Motor ingredients for the assessment in chronic stroke. NeuroRehabilitation, 35(3), 435–449. https://doi.org/10.3233/NRE-141134
82. Zafar, S., Siddiqi, A., Yasir, M., & Zachar, J. J. (2021). Pedagogical development in local anaesthetic training in paediatric dentistry using virtual reality simulator. Eur Arch Paediatr Dent, 22(4), 667–674. https://doi.org/10.1007/s40368-021-00604-7