HİDRADENİTİS SUPURATİVA HASTALARINDA FOLİK ASİT VE HBA1C DEĞERLERİNİN KORELASYONU

Öz

Hidradenitis supurativa (HS) esasen folikülopilosebase üniteyi etkileyen, özellikle aksillar , inguinal , perianal, genital ve inframamarian gibi apokrin bezden zengin deri bölgelerini tutan kronik, ağrılı , folliküler, okluziv kutanöz bir hastalıktır. HS patogenezi tam olarak anlaşılamamıştır. Bağışıklık sisteminin disregülasyonu HS etyolojisine katkıda bulunabilir. Genetik, diyet, sigara kullanımı, obezite, mekanik travma ve hormonal faktörler HS ile ilişkili olabilir. Rektospektif çalışmamızda hastalarımızda HS’ye eşlik eden faktörler olarak daha önce birkaç yazıda bahsedilen diyabet ve folik asit eksikliği ile ilgili verileri gözden geçirmeyi amaçladık. Çalışmamızda 24 hastanın 1/3'ünde HbA1c seviyesinin yüksek olduğu, sadece 4 hastada folik asit seviyesinin istenilen değerde olduğu saptandı. Bu sınırlı sayıdaki veri, bu konuda daha fazla çalışma yapılması fikrini destekler niteliktedir.

Anahtar Kelimeler

• folik asit
• hidradenitis supurativa
• HbA1c

HBA1C AND FOLIC ACID VALUES IN PATIENTS WITH HYDRADENITIS SUPURATIVA

Öz

Hidradenitis supurativa (HS) is a chronic, follicular and occlusive cutaneous disease that mainly affects the folliculopilosebaceous unit, especially in areas of skin which is rich in apocrine glands such as axillary, inguinal, perianal, genital and inframammary regions. The pathogenesis of HS is not understood completely. Dysregulation of the immune system may contribute to HS etiology. Genetics, diet, smoking, obesity, mechanical trauma hormonal factors may be associated with HS (1,2). In our retrospective study, we aimed to review the data on diabetes and folic acid deficiency, which were mentioned in a few articles before, as factors accompanying HS in our patients. We found that 1/3 of 24 patients had high HbA1c levels, and folic acid levels were at the desired value in only four patients. This limited number of data seems to support the idea of further studies on this subject.

Anahtar Kelimeler

• folic acid
• hydradenitis supurativa
• HbA1c

Kaynakça

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