The Effects of Repetitive Running on Middle-Distance Runners’ Muscle Damage Level

Öz

The aim of this study was to examine the effect of repetitive running on middle distance athletes’ muscle damage. There were 24 female middle-distance athletes who have attended training regularly voluntarily participated in this study. Participants were randomly divided two groups which were experimental (n=12) and control (n=12) groups. Experimental group participants’ mean age, height and weight were (20.90±1.05 year, 160.67±3.20 cm, 57.20±3.07kg, respectively). Control group participants’ mean age, height and weight were (21.13±.64 year, 164.88±4.52cm, 58.13±3.48kg, respectively). Participants’ CK, LDH, Urea, Uric Acid, Creatine, HDL, LDL, Triglyceride, Total Cholesterol, Glucose, ALT and AST values were collected before and after 8 weeks repetitive running training. Data were analyzed with SPSS 24.0 package programme. As a result, it showed that LDH¸ uric acid and creatinine values increased significantly in both groups post-test values. There was no statistically significant difference in pre-post test, CK, Urea, ALT, AST, Glucose, HDL, LDL, Triglyceride and Total Cholesterol values Repetitive running training positively increased LDH levels, while positively decreasing creatine and uric acid levels. As a conclusion, 8 weeks repetitive running training positively affected middle distance athletes’ LDH, creatine and urea levels. Applied training program did not affect other values which are used for determining muscle damage. 

Anahtar Kelimeler

• Repetitive running
• Middle distance runners
• Muscle damage

Orta Mesafe Koşucularında Tekrarlı Koşuların Kas Hasarına Etkisi

Öz

Bu çalışmanın amacı, tekrarlı koşuların orta mesafe sporcularının kas hasarı üzerindeki etkisini incelemektir. Bu çalışmaya düzenli olarak gönüllü olarak antrenmanlara katılan 24 bayan orta mesafe sporcusu katılmıştır. Katılımcılar rastgele olarak deney (n=12) ve kontrol (n=12) grupları olmak üzere iki gruba ayrıldı. Deney grubu katılımcılarının yaş, boy ve kilo ortalamaları (sırasıyla 20.90±1.05 yıl, 160.67±3.20 cm, 57.20±3.07kg) idi. Kontrol grubu katılımcılarının yaş, boy ve kilo ortalamaları (sırasıyla 21.13±.64 yıl, 164.88±4.52cm, 58.13±3.48kg) idi. Sporcuların kas hasarını belirlemek için iki grup ön ve son test deney tasarımı kullanılmıştır. Katılımcıların CK, LDH, Üre, Ürik Asit, Kreatin, HDL, LDL, Trigliserit, Toplam Kolesterol, Glikoz, ALT ve AST değerleri 8 haftalık tekrarlı koşu antrenmanı öncesi ve sonrasında toplandı. Veriler SPSS 24.0 paket programı ile analiz edilmiştir. Sonuç olarak, LDH¸ ürik asit ve kreatin değerlerinin her iki grupta da son test değerlerinin önemli ölçüde arttığını gösterdi. Ön-son test, CK, Üre, ALT, AST, Glikoz, HDL, LDL, Trigliserit ve Toplam Kolesterol değerlerinde ise istatistiksel açıdan anlamlı fark yoktu. Tekrarlayan koşu antrenmanları, LDH düzeylerini olumlu yönde artırırken, kreatin ve ürik asit düzeylerini olumlu yönde azalttı. Sonuç olarak, 8 haftalık tekrarlı koşu antrenmanı orta mesafe sporcularının LDH, kreatin ve üre düzeylerini olumlu yönde etkilemiştir. Uygulanan antrenman programı, kas hasarını belirlemede kullanılan diğer değerleri etkilemedi.

Anahtar Kelimeler

• Tekrarlı koşu
• Orta mesafe koşucuları
• Kas hasarı

Kaynakça

1. Arakawa, K., Hosono, A., Shibata, K., Ghadimi, R., Fuku, M., Goto, C., ... & Tokudome, S. (2016). Changes in blood biochemical markers before, during, and after a 2-day ultramarathon. Journal of Sports Medicine, 7,43-50. https://doi.org/10.2147/OAJSM.S97468
2. Bailey, D. M., McEneny, J., Mathieu-Costello, O., Henry, R. R., James, P. E., McCord, J. M., ... & Richardson, R. S. (2010). Sedentary aging increases resting and exercise-induced intramuscular free radical formation. Journal of Applied Physiology, 109(2), 449-456. https://doi.org/10.1152/japplphysiol.00354.2010
3. Boulter, J., Noakes, T. D., & Hew-Butler, T. (2011). Acute renal failure in four Comrades Marathon runners ingesting the same electrolyte supplement: Coincidence or causation? South African Medical Journal, 101(12), 876-878.
4. Brancaccio, P., Maffulli, N., & Limongelli, F. M. (2007). Creatine kinase monitoring in sport medicine. British Medical Bulletin, 81(1),209-230. https://doi.org/10.1093/bmb/ldm014
5. Clark, J. M., Brancati, F. L., & Diehl, A. M. (2003). The prevalence and etiology of elevated aminotransferase levels in the United States. The American Journal of Gastroenterology, 98(5), 960-967. https://doi.org/10.1016/S0002-9270(03)00265-X
6. Clarkson, P. M., & Hubal, M. J. (2002). Exercise-induced muscle damage in humans. American Journal of Physical Medicine & Rehabilitation, 81(11), S52-S69. https://doi.org/10.1097/00002060-200211001-00007
7. Dahl, J., Degens, H., Hildebrand, F., & Ganse, B. (2020). Do changes in middle-distance running kinematics contribute to the age-related decline in performance? Journal of Musculoskeletal & Neuronal Interactions, 20(1), 94-100.
8. Freitas, V. H., Nakamura, F. Y., Miloski, B., Samulski, D., & Bara-Filho, M. G. (2014). Sensitivity of physiological and psychological markers to training load intensification in volleyball players. Journal of Sports Science & Medicine, 13(3), 571-579.

9. Fu, F. H., You, C. Y., & Kong, Z. W. (2002). Acute changes in selected serum enzyme and metabolite concentrations in 12-to 14-Yr.-old athletes after an all-out 100-m swimming sprint. Perceptual and Motor Skills, 95(3), 1171-1178. https://doi.org/10.2466/pms.2002.95.3f.1171
10. Heung, M., Steffick, D. E., Zivin, K., Gillespie, B. W., Banerjee, T., Hsu, C. Y., ... & Waller, L. (2016). Acute kidney injury recovery pattern and subsequent risk of CKD: An analysis of veteran’s health administration data. American Journal of Kidney Diseases, 67(5), 742-752. https://doi.org/10.1053/j.ajkd.2015.10.019
11. Hsu, R. K., & Hsu, C. Y. (2016). The role of acute kidney injury in chronic kidney disease. Seminars in Nephrology, 36(4), 283-292. https://doi.org/10.1016/j.semnephrol.2016.05.005
12. Karstoft, K., Solomon, T. P., Laye, M. J., & Pedersen, B. K. (2013). Daily marathon running for a week the biochemical and body compositional effects of participation. The Journal of Strength & Conditioning Research, 27(11), 2927-2933. https://doi.org/10.1519/JSC.0b013e318289e39d
13. Kratz, A., Lewandrowski, K. B., Siegel, A. J., Chun, K. Y., Flood, J. G., Van Cott, E. M., & Lee-Lewandrowski, E. (2002). Effect of marathon running on hematologic and biochemical laboratory parameters, including cardiac markers. American Journal of Clinical Pathology, 118(6), 856-863. https://doi.org/10.1309/14TY-2TDJ-1X0Y-1V6V
14. Lippi, G., Tarperi, C., Salvagno, G. L., Benati, M., Danese, E., Montagnana, M., ... & Schena, F. (2019). Comparison of plasma lipids changes after middle-distance running in euglycemic and diabetic subjects. Journal of Public Health Emergency, 3(10), 1-5. https://doi.org/10.21037/jphe.2019.06.01
15. Moflehi, D., Kok, L. Y., Tengku-Fadilah, T. K., & Amri, S. (2012). Effect of single-session aerobic exercise with varying intensities on lipid peroxidation and muscle-damage markers in sedentary males. Global Journal of Health Science, 4(4), 48-54. https://doi.org/10.5539/gjhs. v4n4p48
16. Mohamed, S., Lamya, N., & Hamda, M. (2016). Effect of maximal versus supra-maximal exhausting race on lipid peroxidation, antioxidant activity and muscle-damage biomarkers in long-distance and middle-distance runners. Asian Journal of Sports Medicine, 7(1), 1-8. https://doi.org/10.5812/asjsm.27902
17. Morris, J. G., Nevill, M. E., & Williams, C. (2000). Physiological and metabolic responses of female games and endurance athletes to prolonged, intermittent, high-intensity running at 30° and 16° C ambient temperatures. European Journal of Applied Physiology, 81(1), 84-92. https://doi.org/10.1007/PL00013801
18. Nie, J., Tong, T. K., George, K., Fu, F. H., Lin, H., & Shi, Q. (2011). Resting and post‐exercise serum biomarkers of cardiac and skeletal muscle damage in adolescent runners. Scandinavian Journal of Medicine & Science in Sports, 21(5), 625-629. https://doi.org/10.1111/j.1600-0838.2010. 01096.x
19. Park, K. S. (2006). Exercise-induced muscle damage and immune cell apoptosis. Doctoral Thesis. Purdue University West Lafayette, Indiana
20. Proia, P., Giaccone, M., Contrò, V., Bianco, A., Traina, M., & Palma, A. (2015). Oxidative stress markers associated with middle distance running performance. Journal of Biological Research, 88(1), 119. https://doi.org/10.1007/BF00602366
21. Reilly, T., Secher, N., Snell, P., Williams, C., & Williams, C. (2005). Physiology of sports. Routledge.
22. Rojas-Valverde, D., Sánchez-Ureña, B., Pino-Ortega, J., Gómez-Carmona, C., Gutiérrez-Vargas, R., Timón, R., & Olcina, G. (2019). External workload indicators of muscle and kidney mechanical injury in endurance trail running. International Journal of Environmental Research and Public Health, 16(20), 3909. https://doi.org/10.3390/ijerph16203909
23. Roncal-Jimenez, C., Lanaspa, M. A., Jensen, T., Sanchez-Lozada, L. G., & Johnson, R. J. (2015). Mechanisms by which dehydration may lead to chronic kidney disease. Annals of Nutrition and Metabolism, 66(Suppl. 3), 10-13. https://doi.org/10.1159/000381239
24. Siahpoosh, A. K., & Nesaei, A. (2016). The Effect of Caffeine Supplementation on Blood Lactate and Glucose after 800- and 1500-meter Run. Biomedical and Pharmacology Journal, 9(1), 97-103. https://doi.org/10.13005/bpj/914
25. Tiidus, P. M. (2008). Skeletal muscle damage and repair. Human Kinetics.
26. Tirabassi, J. N., Olewinski, L., & Khodaee, M. (2018). Variation of traditional biomarkers of liver injury after an ultramarathon at altitude. Sports Health, 10(4),361-365. https://doi.org/10.1177/1941738118764870
27. Totsuka, M., Nakaji, S., Suzuki, K., Sugawara, K., & Sato, K. (2002). Break point of serum creatine kinase release after endurance exercise. Journal of Applied Physiology, 93(4), 1280-1286. https://doi.org/10.1152/japplphysiol.01270.2001
28. Westerbacka, J., Corner, A., Tiikkainen, M., Tamminen, M., Vehkavaara, S., Häkkinen, A. M., ... & Yki-Järvinen, H. (2004). Women and men have similar amounts of liver and intra-abdominal fat, despite more subcutaneous fat in women: Implications for sex differences in markers of cardiovascular risk. Diabetologia, 47(8), 1360-1369. https://doi.org/10.1007/s00125-004-1460-1
29. Weyand, P. G., Cureton, K. J., Conley, D. S., Sloniger, M. A., & Liu, Y. L. (1994). Peak oxygen deficit predicts sprint and middle-distance track performance. Medicine and Science in Sports and Exercise, 26(9), 1174-1180.
30. Wong, V. W. S., Chu, W. C. W., Wong, G. L. H., Chan, R. S. M., Chim, A. M. L., Ong, A., ... & Chan, H. L. Y. (2012). Prevalence of non-alcoholic fatty liver disease and advanced fibrosis in Hong Kong Chinese: A population study using proton-magnetic resonance spectroscopy and transient elastography. Gut, 61(3),409-415. https://doi.org/10.1136/gutjnl-2011-300342