Intoxication Cases Admitted to Edirne State Hospital Emergency Department Between 2006-2008 and 2017-2019: A Retrospective (10- year change)

Yıl 2026, Cilt: 16 Sayı: 1, 103 - 110, 19.03.2026

Güldan Vapur , Mustafa Yıldız , Metin Budak , Uğur Özkan Murat Şahin

https://izlik.org/JA96FC33AB

Öz

Aim: Poisoning cases are increasing day by day in our country. Each country's poisoning profile differs. The aim of this study was to investigate the ten-year change in poisoning cases admitted to Edirne State Hospital Emergency Department between 2006-2008 and 2017-2019.
Materials and methods: In this study, demographic characteristics such as age, gender, season, month, day, arrival time, type of intoxication, route of poisoning and poisoning agent, which were admitted to Edirne State Hospital. A total of 1025 intoxication cases were recorded between 2006–2008, and 968 cases between 2017–2019.
Results: During 2006–2008, 58.6% of intoxication cases were women and 41.4% were men, whereas during 2017–2019, 53.9% were women and 46.1% were men. Poisonings occurred mostly in summer and winter in both study periods. In the first period, the highest rates were in January, June, and August, while in the later period, they were in October and July. In both study periods, the highest number of admissions occurred in the 21–30 age group, and oral ingestion was the most common route of poisoning. Drug intoxications increased from 46.8% in the first period to 64.9% in the second.
Conclusion: Significant differences were observed between the two periods in terms of months of admission, gender, age distribution, poisoning agents, routes of exposure, and types of intoxication.

Anahtar Kelimeler

Drug , Emergency , Intoxication , Suicide

Kaynakça

• 1. Kundu P, Das S, Chattopadhyay N. Managing efficacy and toxicity of drugs: Targeted delivery and excretion. Int J Pharm. 2019;565:378–390. https://doi.org/10.1016/j.ijpharm.2019.04.058
• 2. Roberts SM, James RC, Williams PL. Principles of toxicology: environmental and industrial applications. John Wiley & Sons; 2022.
• 3. Alves VM, Francisco LC, de Melo AR, Novaes CR, Belo FM, Nardi AE. Trends in suicide attempts at an emergency department. Braz J Psychiatry. 2017;39(1):55–61. https://doi.org/10.1590/1516-4446-2015-1833
• 4. Nadarajah P, Hayden MJ. Poisoning. Hosp Med. 2004;65(3):174–177. https://doi.org/10.12968/hosp.2004.65.3.12402
• 5. Karaarslan B, Turla A, Aydın B. Corrosive poisoning cases consulted at OMU Faculty of Medicine, Emergency Service. Van Med J. 2007;14(4):109–113.
• 6. Bronstein AC, Spyker DA, Cantilena LR Jr, Green JL, Rumack BH, Giffin SL. 2008 annual report of the American Association of Poison Control Centers’ National Poison Data System (NPDS): 26th Annual Report. Clin Toxicol (Phila). 2009;47(10):911–1084. https://doi.org/10.3109/15563650903438566
• 7. Mowry JB, Spyker DA, Brooks DE, McMillan N, Schauben JL. 2014 annual report of the American Association of Poison Control Centers’ National Poison Data System (NPDS): 32nd Annual Report. Clin Toxicol (Phila). 2015;53(10):962–1147. https://doi.org/10.3109/15563650.2015.1102927
• 8. Özcan N, İkincioğulları D. Ulusal Zehir danışma merkezi 2008 yılı çalışma raporu özeti. Turk Hij Den Biyol Derg. 2009;66:29–58.
• 9. Arikan M, Yeşilkaya A, Taşdelen BN, Özyiğit İ. A retrospective analysis of intoxicated patients admitted to the intensive care unit: a single-institution assessment in the post-pandemic period. J Biosci Med (Irvine). 2024;12(03):159–167. https://doi.org/10.4236/jbm.2024.123014
• 10. Zhang Y, Yu B, Wang N, Li T. Acute poisoning in Shenyang, China: a retrospective and descriptive study from 2012 to 2016. BMJ Open. 2018;8(8):e021881. https://doi.org/10.1136/bmjopen-2018-021881
• 11. Deniz T, Kandiş H, Saygun M, Büyükkoçak Ü, Ülger H, Karakuş A. Kırıkkale Üniversitesi Tıp Fakültesi acil servisine başvuran zehirlenme olgularının analizi. Duzce Med J. 2009;11(2):15–20.
• 12. Ahmadi A, Pakravan N, Ghazizadeh Z. Pattern of acute food, drug, and chemical poisoning in Sari City, Northern Iran. Hum Exp Toxicol. 2010;29(9):731–738. https://doi.org/10.1177/0960327110361501
• 13. Avsarogullari L, Senol V, Akdur O, Akin A, Durukan P, Ozkan S. Characteristics of acute adult poisonings in a university hospital emergency department in central Turkey: a three-year analysis. J Pak Med Assoc. 2012;62(2):129–133.
• 14. Tangiisuran B, Jiva M, Ariff AM, Abdul Rani NA, Misnan A, Rashid SM, et al. Evaluation of types of poisoning exposure calls managed by the Malaysia National Poison Centre (2006-2015): a retrospective review. BMJ Open. 2018;8(12):e024162. https://doi.org/10.1136/bmjopen-2018-024162
• 15. Taghaddosinejad F, Yaghmaei A, Mehrpour O, Schwake L. Epidemiology and treatment of severe poisoning in the intensive care unit: lessons from a one-year prospective observational study. J Clin Toxicol. 2012;01(S1):007. https://doi.org/10.4172/2161-0495.S1-007.
• 16. Maharani B, Vijayakumari N. Profile of poisoning cases in a tertiary care hospital, Tamil Nadu, India. J Appl Pharm Sci. 2013;3(1):91–94. https://doi.org/10.7324/JAPS.2013.30117.
• 17. Singh O, Javeri Y, Juneja D, Gupta M, Singh G, Dang R. Profile and outcome of patients with acute toxicity admitted in intensive care unit: experiences from a major corporate hospital in urban India. Indian J Anaesth. 2011;55(4):370–374. https://doi.org/10.4103/0019-5049.84860
• 18. Kiyan S, Özsaraç M, Ersel M, Yürüktümen A, Karahalli E, Özçete E, et al. Analysis of patients with acute intoxication in a two year period. Turk J Emerg Med. 2009;9(1):24–30.
• 19. Kurt İ, Erpek AG, Kurt MN, Gürel A. Epidemiology of adult poisoning at Adnan Menderes University. Meandros Med Dent J. 2004;5(3):37–40.
• 20. Fergusson DM, Woodward LJ, Horwood LJ. Risk factors and life processes associated with the onset of suicidal behaviour during adolescence and early adulthood. Psychol Med. 2000;30(1):23–39. https://doi.org/10.1017/S003329179900135X
• 21. Akçay A, Gürses D, Özdemir A, Kılıç İ, Ergin H. Denizli ilindeki çocukluk çağı zehirlenmeleri. Adnan Menderes Üniversitesi Tıp Fakültesi Derg. 2005.
• 22. Magalhães APNd, Alves VdM, Comassetto I, Lima PC, Faro ACM, Nardi AE. Atendimento a tentativas de suicídio por serviço de atenção pré-hospitalar. J Bras Psiquiatr. 2014;63:16–22. https://doi.org/10.1590/0047-2085000000003
• 23. Sungur S, Bilge U, Acar N, Unluoglu I. Retrospective evaluation of adult poisoning cases admitted to emergency department of a University Hospital in Turkey. Niger J Clin Pract. 2018;21(8):1023–1028. https://doi.org/10.4103/njcp.njcp_291_17
• 24. Sert AI, Kiliç ET, Akdemir MS, Kavak GÖ. Retrospective analysis of organophosphate poisonings in an intensive care unit in Turkey: a single-center study. Dubai Med J. 2018;1(1-4):13–18. https://doi.org/10.1159/000493768
• 25. Turcu TA, Lescaie A, Grama AR, Stratula AC, Vincene AI, Grigoras LM, et al. Patterns and emerging trends in acute poisoning with substances of abuse used for recreational purposes in adolescents: a six-year multicentre study. Life (Basel). 2024;14(8):1033. https://doi.org/10.3390/life14081033
• 26. Alharbi AA, Muaddi MA, Binhotan MS, Alqassim AY, Alsultan AK, Arafat MS, et al. Poisoning epidemiology, clinical outcomes and management decisions for general public calls: a cross-sectional analysis of a nationwide telehealth toxicology consultation service data in Saudi Arabia. J Epidemiol Glob Health. 2025;15(1):60. https://doi.org/10.1007/s44197-025-00404-y
• 27. Lei R, Yue C, Yue F, Gao H, He X, Yan Q, et al. Burden of non-CO poisoning in 204 countries and territories, 1990-2021: results from the global burden of disease study 2021. Front Public Health. 2025;13:1620523. https://doi.org/10.3389/fpubh.2025.1620523