Prognostic Usage of Lactate Levels in Patients with Upper Gastrointestinal Bleeding

Yıl 2018, , 115 - 120, 01.08.2018

İbrahim Can Ayık Vermi Değerli Gökhan Yılmaz , Emre Sevim

https://doi.org/10.5505/kjms.2018.15945

Öz

Aim: Glasgow Blatchford Score (GBS) and Rockall score is the
most widely used scoring system for risk classification of patients
with upper gastrointestinal bleeding. Lactate levels is not used by
any of those scoring systems. Lactate levels is a determinant factor in a variety of conditions including shock, trauma and sepsis.
The aim of our study was to investigate prognostic value of serum
lactate levels in patients who have GI bleeding.
Material and Method: Patients with the age 18 and older who
were diagnosed upper gastrointestinal system bleeding, between
May 1, 2015 and May 31, 2016, were enrolled in the study. The
age, sex, hemoglobin and lactate values in emergency admission,
the need for blood transfusion, chronic disease and GBS values
were recorded in the data sheet. We investigated the association
between blood transfusion and intensive care with lactate level.
SPSS 22.0 (IBM Corporation, Armonk, New York, United States)
program was used to analyze the variables.
Results: 78 patients were included in the study. 27 patients
(34.6%) were female and 51 (65.4) were male. The mean age was
67.6±17.75 (min: 22, max: 100). The median lactate levels were 2.2
mmol/L for patients who need blood transfusion and 1.9 mmol/L
for patients who who didn’t need. . This difference was not statistically significant (p=0.450). The median lactate levels were 3.9
mmol/L for patients who hospitalized in intensive care and 1.9
mmol/L for patients who did not need intensive care. This difference was statistically significant (p=0.038).
Conclusion: In our study, significant relationship between intensive care hospitalization and lactate levels was found; but between
the need for blood transfusion and lactate levels we didn’t find a
significant relationship

Anahtar Kelimeler

lactate; gastrointestinal; bleeding; blood transfusion; intensive care

Laktat Seviyesinin Üst Gastrointestinal Sistem Kanamalı Hastalarda Prognostik Amaçlı Kullanımı

Öz

Amaç: Üst GİS kanamalı hastaların risk sınıflandırılmasında en çok
Glasgow Blatchford Skoru (GBS) ve Rockall Skoru kullanılmaktadır.Bu skorlama sistemlerinin hiçbirinde serum laktat seviyesi kullanılmamaktadır. Laktat seviyesi travma ve sepsis dahil çeşitli şok
durumlarında mortalite beliryecisidir. Çalışmamızın amacı üst GİS
kanamalı hastalarda serum laktat seviyesinin prognostik amaçlı kullanımını araştırmaktır.
Materyal ve Metot: 1 Mayıs 2015 ve 31 Mayıs 2016 tarihleri arasında, üst gastrointestinal sistem (GİS) kanaması tanısı konmuş 18
yaş ve üstü hastalar çalışmaya alındı. Hastaların yaş, cinsiyet, acil
servis kabulündeki hemoglobin ve laktat değeri, kan transfüzyon ihtiyacı, kronik hastalıkları ve GBS değerleri veri formuna kaydedildi.
Kan transfüzyon ve yoğun bakım ihtiyacı ile laktat düzeyi arasındaki
ilişki araştırıldı. Değişkenlerin analizinde SPSS 22.0 (IBM Corparation,
Armonk, New York, United States) programı kullanıldı.
Bulgular: Çalışmaya 78 hasta dahil edildi. Hastaların 27’si (%34,6)
kadın, 51’i (65,4) erkekti. Yaş ortalaması 67,6±17,75 (min: 22, max:
100) olarak saptandı. Kan transfüzyonu yapılan hastaların median
laktat değeri 2,2 mmol/L, kan transfüzyonu yapılmayan hastaların
median laktat değeri 1,9 mmol/L olarak bulundu. Bu fark istatiksel
olarak anlamlı bulunmadı (p=0,450). Servise yatan hastaların median laktat değeri 1,9 mmol/L, yoğun bakıma yatan hastaların median
laktat değeri 3,9 mmol/L bulundu. Bu iki grup arasındaki fark istatiksel olarak anlamlı bulundu (p=0,038).
Sonuç: Üst GİS kanamalı hastalarda yoğun bakım ve servis yatışları ile laktat düzeyi arasında anlamlı ilişki saptanmışken; kan transfüzyonu alan ve almayan hastalar arasında laktat düzeyi açısından
anlamlı bir ilişki saptanmamıştır 

Anahtar Kelimeler

laktat; gastrointestinal; kanama; kan transfüzyonu; yoğun bakım

Kaynakça

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