Gestasyonel Diyabet, Metabolik Sendrom ile İlişkili midir?

Emel Arslan Yıldırım; Mehmet Bülbül; Kemal Özerkan; Osman Haldun Develioğlu

Gestasyonel Diyabet, Metabolik Sendrom ile İlişkili midir?

Öz

Amaç: Gestasyonel Diabetes Mellitus (GDM) gebeliklerin %1-14’ünü görülür. Polikistik over sendromu (PCOS) ve metabolik sendromda (MS) olduğu gibi patofizyolojisinde insülin direnci (IR) rol alır. Bundan dolayı bu üç klinik durumun birbiriyle ilişkili olduğu düşünülmektedir. Materyal ve Metot: Bu çalışmada GDM tanısı almış 27 kadın ve sağlıklı 30 kadın PCOS, MS ve IR açısından karşılaştırılmıştır. Bulgular: GDM grubunda kilo ve vücut kitle indeksi (BMI), bel ve kalça çevreleri kontrol grubundan daha yüksekti (sırasıyla 69.0±11,5 kg vs 62.0±10,3 kg, p:0,01; 27.0±4,7 kg/m2 vs 23.0±3,5 kg/m2, p:0,001; 82.0±8,5 cm vs 74.0±7,5 cm, p<0,001; 103.0±8,1 cm vs 98.0±8,7 cm, p:0,02). MS sıklığı GDM grubunda kontrol grubuna göre istatistiksel anlamlı olarak daha yüksekti. Bel çevresi, kan basıncı, açlık kan şekeri ve trigliserid düzeyleri yüksek olan hasta sayısı kontrol grubuna göre daha fazlaydı (sırasıyla %55,6 vs %20, p:0,006; %18,5 vs %0, p:0,01; %29,6 vs %6,7, p:0,02; %48,1 vs %10, p: 0,002). HDL kolesterol düzeyi açısından ise gruplar arasında istatistiksel olarak fark saptanmadı (p>0,05). HOMA için eşik değer 2.24 olarak alındığında GDM grubunda kontrol grubundan daha fazla insülin direnci saptandı sırasıyla (sırasıyla %48,1 vs %20,0, p: 0,02). Sonuç: GDM’de olduğu gibi MS ve PCOS’ta ortak problem IR’dır. Birçok çalışmada gösterildiği gibi bizim çalışmamızda da MS, GDM grubunda daha yüksek saptandı. Bundan dolayı GDM öyküsü olan hastalarda metabolik sendrom taranmalıdır

Anahtar Kelimeler

gestasyonel diyabet; insulin direnci; metabolik sendrom; polikistik over sendromu

Kaynakça

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Ayrıntılar

Birincil Dil

İngilizce

Konular

Klinik Tıp Bilimleri

Bölüm

Araştırma Makalesi

Yazarlar

Emel Arslan Yıldırım Bu kişi benim
Türkiye

Mehmet Bülbül Bu kişi benim
Türkiye

Kemal Özerkan Bu kişi benim
Türkiye

Osman Haldun Develioğlu Bu kişi benim
Türkiye

Yayımlanma Tarihi

1 Ağustos 2019

Gönderilme Tarihi

24 Mayıs 2018

Kabul Tarihi

24 Mayıs 2019

Yayımlandığı Sayı

Yıl 2019 Cilt: 9 Sayı: 2

IZ

https://izlik.org/JA73DP37YR

Kaynak Göster

RIS / Bibtex

APA

Yıldırım, E. A., Bülbül, M., Özerkan, K., & Develioğlu, O. H. (2019). Gestasyonel Diyabet, Metabolik Sendrom ile İlişkili midir? Kafkas Journal of Medical Sciences, 9(2), 110-116. https://izlik.org/JA73DP37YR

AMA

1.Yıldırım EA, Bülbül M, Özerkan K, Develioğlu OH. Gestasyonel Diyabet, Metabolik Sendrom ile İlişkili midir? KAFKAS TIP BİL DERG. 2019;9(2):110-116. https://izlik.org/JA73DP37YR

Chicago

Yıldırım, Emel Arslan, Mehmet Bülbül, Kemal Özerkan, ve Osman Haldun Develioğlu. 2019. “Gestasyonel Diyabet, Metabolik Sendrom ile İlişkili midir?”. Kafkas Journal of Medical Sciences 9 (2): 110-16. https://izlik.org/JA73DP37YR.

EndNote

Yıldırım EA, Bülbül M, Özerkan K, Develioğlu OH (01 Ağustos 2019) Gestasyonel Diyabet, Metabolik Sendrom ile İlişkili midir? Kafkas Journal of Medical Sciences 9 2 110–116.

IEEE

[1]E. A. Yıldırım, M. Bülbül, K. Özerkan, ve O. H. Develioğlu, “Gestasyonel Diyabet, Metabolik Sendrom ile İlişkili midir?”, KAFKAS TIP BİL DERG, c. 9, sy 2, ss. 110–116, Ağu. 2019, [çevrimiçi]. Erişim adresi: https://izlik.org/JA73DP37YR

ISNAD

Yıldırım, Emel Arslan - Bülbül, Mehmet - Özerkan, Kemal - Develioğlu, Osman Haldun. “Gestasyonel Diyabet, Metabolik Sendrom ile İlişkili midir?”. Kafkas Journal of Medical Sciences 9/2 (01 Ağustos 2019): 110-116. https://izlik.org/JA73DP37YR.

JAMA

1.Yıldırım EA, Bülbül M, Özerkan K, Develioğlu OH. Gestasyonel Diyabet, Metabolik Sendrom ile İlişkili midir? KAFKAS TIP BİL DERG. 2019;9:110–116.

MLA

Yıldırım, Emel Arslan, vd. “Gestasyonel Diyabet, Metabolik Sendrom ile İlişkili midir?”. Kafkas Journal of Medical Sciences, c. 9, sy 2, Ağustos 2019, ss. 110-6, https://izlik.org/JA73DP37YR.

Vancouver

1.Emel Arslan Yıldırım, Mehmet Bülbül, Kemal Özerkan, Osman Haldun Develioğlu. Gestasyonel Diyabet, Metabolik Sendrom ile İlişkili midir? KAFKAS TIP BİL DERG [Internet]. 01 Ağustos 2019;9(2):110-6. Erişim adresi: https://izlik.org/JA73DP37YR