Endemik Bölgelerde Bruselloz Tanısında Serolojik Testlerin Kombinasyonu

Yıl 2014, Yıl: 2014 Sayı: 1, 19 - 22, 01.03.2014

Mehmet Balcı Çiğdem Kader Neziha Yılmaz Mehmet Uyar Yalçın Erdoğan

Öz

AMAÇ: Bu çalıșmada RBPT ve/veya STAT testleri negatif olan klinik
ve epidemiyolojik olarak bruselloz ile uyumlu hastalarda RBPT,
STAT ve ELISA kombinasyonunun tanıdaki etkinliğinin değerlendirilmesi
amaçlandı.
YÖNTEM: Klinik ve epidemiyolojik olarak brusellozla uyumlu 66 olgunun
serum örneği RBPT, STAT ve ELISA ile test edildi. RBT pozitif ve
negatif kișilerde STAT ve/veya ELISA test sonuçları seropozitifl ik yö-
nünden karșılaștırıldı. Veriler SPSS 16.0 bilgisayar programına girildi.
Sonuçların istatistiksel analizi için Fischer Exact testi yapıldı. p

Anahtar Kelimeler

Bruselloz, tanısal testler, rutin, serolojik testler

Combination of The Serological Tests For The Diagnosis of Brucellosis in Endemic Areas

Öz

AIM: The aim of the study is to analyze the effi ciency of combination
of RBPT, STAT and ELISA tests on patients with brucellosis
where the diagnosis is dependent on the compatible clinical and
epidemiological fi ndings with negative RBPT and/or STAT test
results.
METHODS: The serum samples of 66 patients having clinical and
epidemiological fi ndings compatible with brucellosis were analyzed
using the combination of RBPT, STAT and ELISA tests. Both
positive and negative samples were re-analyzed for seropositivity
by using the STAT or ELISA tests together. The results were statistically
analyzed with the SPSS 16.0 computer program using the
Fisher Exact test. The signifi cance level was defi ned as p< 0.05.
RESULTS: Serum samples tested for brucellosis using the RBPT
were found to be seropositive in 45.5% and seronegative in 54.5%.
The seropositive group had a 73% seropositivity with the combination
of STAT and ELISA tests. The seronegative group also had a
25% seropositivity with the combination of STAT and ELISA tests.
Both groups’ seropositivity rate signifi cantly increased after the
combination of the tests (p< 0.05).
CONCLUSION: It seems that the combination of RBPT, STAT
and ELISA tests increases the rate of seropositivity in patients with
negative RBPT and /or STAT tests, particularly with a pre–diagnosis
of brucellosis.

Anahtar Kelimeler

Brucellosis, diagnostic tests, routine, serological tests