Araştırma Makalesi
BibTex RIS Kaynak Göster
Yıl 2022, Cilt: 12 Sayı: 2, 127 - 134, 31.08.2022

Öz

Kaynakça

  • 1. Fang Y, Zhang H, Xie J, Lin M, Ying L, Pang P el al. Sensitivity of Chest CT for COVID-19: Comparison to RT-PCR. Radiology.2020 Aug;292(2):E115- e117.doi:10.1148/radiol.2020200432.
  • 2. Guan CS, Lv ZB, Yan S, Du YN, Chen E, Wei LG et al. Imagıng Features of Coronavırus disease 2019 (COVID-19): Evaluation on Thin-Section CT. Acad Radiol.2020 May;27(5):609-613. doi:10.1016/j.acra.2020.03.002.
  • 3. Koo HJ, Lim S, Choe J, Choi SH, Sung H, Do KH. Radiographic and CT Features of Viral Pneumonia. Radiographics. 2018 May-Jun;38(3):719-739. doi: 10.1148/rg.2018170048.
  • 4. Colombi D, Bodini FC, Petrini M, Maffi G, Morelli N, Milanese G et al. Well-aerated Lung on Admitting Chest CT to Predict Adverse Outcome in COVID-19 Pneumonia. Radiology. 2020 Aug;296(2):E86-E96. doi: 10.1148/radiol.2020201433.
  • 5. Simpson S, Kay FU, Abbara S, Bhalla S, Chung JH, Chung M et al. Radiological Society of North America Expert Consensus Document on Reporting Chest CT Findings Related to COVID-19: Endorsed by the Society of Thoracic Radiology, the American College of Radiology, and RSNA. Radiol Cardiothorac Imaging. 2020 Mar 25;2(2):e200152. doi: 10.1148/ryct.2020200152.
  • 6. Feng H, Liu Y, Lv M, Zhong J. A case report of COVID-19 with false negative RT-PCR test: necessity of chest CT. Jpn J Radiol. 2020 May;38(5):409-410. doi: 10.1007/s11604-020-00967-9. Epub 2020 Apr 7.
  • 7. Besutti G, Giorgi Rossi P, Iotti V, Spaggiari L, Bonacini R, Nitrosi A et al. Accuracy of CT in a cohort of symptomatic patients with suspected COVID-19 pneumonia during the outbreak peak in Italy. Eur Radiol. 2020 Dec;30(12):6818-6827. doi: 10.1007/s00330-020-07050-x.
  • 8. Gürün, E., Akdulum, İ., & Akyüz, M. (2021). Revealing the dilemma in COVID-19 pneumonia: use of the prone thorax CT imaging in differentiation of opacificities due to dependant zone and pneumonic consolidation. Anatolian Current Medical Journal, 3(1), 78-80. doi:10.38053/acmj.810240
  • 9. Ai T, Yang Z, Hou H, Zhan C, Chen C, Lv W et al. Correlation of Chest CT and RT-PCR Testing for Coronavirus Disease 2019 (COVID-19) in China: A Report of 1014 Cases. Radiology. 2020 Aug;296(2):E32-E40. doi: 10.1148/radiol.2020200642
  • 10. Bai HX, Hsieh B, Xiong Z, Halsey K, Choi JW, Tran TML et al. Performance of Radiologists in Differentiating COVID-19 from Non-COVID-19 Viral Pneumonia at Chest CT. Radiology. 2020 Aug;296(2):E46-E54. doi: 10.1148/radiol.2020200823.
  • 11. Lascarrou JB, Colin G, Le Thuaut A, Serck N, Ohana M, Sauneuf B et al. Predictors of negative first SARS-CoV-2 RT-PCR despite final diagnosis of COVID-19 and association with outcome. Sci Rep. 2021 Jan 27;11(1):2388. doi: 10.1038/s41598-021-82192-6

Comparing The Computed Tomography Findings Of The Covid-19 PCR Positive Patients in Intensive Care Unit and PCR Negative Suspected Patients in Terms of Clinical and Laboratory Data

Yıl 2022, Cilt: 12 Sayı: 2, 127 - 134, 31.08.2022

Öz

Aim: There has been an overload in the workload of intensive care units in the hospitals due the Coronavirus disease 2019 (COVID-19) pandemic, which started in 2019 and caused significant changes in the lives of people. In this process, it is not always easy to distinguish whether the patients followed in the intensive care unit with the suspicion of COVID-19 disease are actually infected or not. Our aim in this study was to reveal possible clinical, laboratory and computed tomography findings between polymerase chain reaction (PCR) (+) and PCR (-) patient groups followed up in the intensive care unit with a preliminary diagnosis of COVID-19.
Material and Method: In this study, we evaluated 83 patients who were confirmed to have COVID-19 by reverse transcription polymerase chain reaction (RT-PCR) and 80 patients who were
RT-PCR negative but clinically and radiologically suspicious for COVID-19. The CT results of the patients were classified in accordance with the categories specified by the Radiological Society of
North America (RSNA). Many laboratory values, clinical progress of the disease, the source of infection and the complaints were also documented. We performed a statistical analysis of the data
obtained between the two patient groups.
Results: The typical radiological appearance was significantly higher in the positive group while the atypical appearance was significantly higher in the suspected group (p = 0.001). There was
no significant difference between the two groups in the indeterminate and negative categories. Regarding the laboratory findings, the means of the Sequential Organ Failure Assessment (SOFA)
score, d-dimer, neutrophil, white blood cell, platelet, neutrophile/ lymphocyte ratio (NLR) were significantly lower in the RT-PCR positive group. There was no significant difference between the
two groups in terms of other laboratory findings.
Conclusion: In conclusion, it was determined that it was hard to distinguish the difference between these patients but there may be some clinical, laboratory and CT results that can facilitate this process.

Kaynakça

  • 1. Fang Y, Zhang H, Xie J, Lin M, Ying L, Pang P el al. Sensitivity of Chest CT for COVID-19: Comparison to RT-PCR. Radiology.2020 Aug;292(2):E115- e117.doi:10.1148/radiol.2020200432.
  • 2. Guan CS, Lv ZB, Yan S, Du YN, Chen E, Wei LG et al. Imagıng Features of Coronavırus disease 2019 (COVID-19): Evaluation on Thin-Section CT. Acad Radiol.2020 May;27(5):609-613. doi:10.1016/j.acra.2020.03.002.
  • 3. Koo HJ, Lim S, Choe J, Choi SH, Sung H, Do KH. Radiographic and CT Features of Viral Pneumonia. Radiographics. 2018 May-Jun;38(3):719-739. doi: 10.1148/rg.2018170048.
  • 4. Colombi D, Bodini FC, Petrini M, Maffi G, Morelli N, Milanese G et al. Well-aerated Lung on Admitting Chest CT to Predict Adverse Outcome in COVID-19 Pneumonia. Radiology. 2020 Aug;296(2):E86-E96. doi: 10.1148/radiol.2020201433.
  • 5. Simpson S, Kay FU, Abbara S, Bhalla S, Chung JH, Chung M et al. Radiological Society of North America Expert Consensus Document on Reporting Chest CT Findings Related to COVID-19: Endorsed by the Society of Thoracic Radiology, the American College of Radiology, and RSNA. Radiol Cardiothorac Imaging. 2020 Mar 25;2(2):e200152. doi: 10.1148/ryct.2020200152.
  • 6. Feng H, Liu Y, Lv M, Zhong J. A case report of COVID-19 with false negative RT-PCR test: necessity of chest CT. Jpn J Radiol. 2020 May;38(5):409-410. doi: 10.1007/s11604-020-00967-9. Epub 2020 Apr 7.
  • 7. Besutti G, Giorgi Rossi P, Iotti V, Spaggiari L, Bonacini R, Nitrosi A et al. Accuracy of CT in a cohort of symptomatic patients with suspected COVID-19 pneumonia during the outbreak peak in Italy. Eur Radiol. 2020 Dec;30(12):6818-6827. doi: 10.1007/s00330-020-07050-x.
  • 8. Gürün, E., Akdulum, İ., & Akyüz, M. (2021). Revealing the dilemma in COVID-19 pneumonia: use of the prone thorax CT imaging in differentiation of opacificities due to dependant zone and pneumonic consolidation. Anatolian Current Medical Journal, 3(1), 78-80. doi:10.38053/acmj.810240
  • 9. Ai T, Yang Z, Hou H, Zhan C, Chen C, Lv W et al. Correlation of Chest CT and RT-PCR Testing for Coronavirus Disease 2019 (COVID-19) in China: A Report of 1014 Cases. Radiology. 2020 Aug;296(2):E32-E40. doi: 10.1148/radiol.2020200642
  • 10. Bai HX, Hsieh B, Xiong Z, Halsey K, Choi JW, Tran TML et al. Performance of Radiologists in Differentiating COVID-19 from Non-COVID-19 Viral Pneumonia at Chest CT. Radiology. 2020 Aug;296(2):E46-E54. doi: 10.1148/radiol.2020200823.
  • 11. Lascarrou JB, Colin G, Le Thuaut A, Serck N, Ohana M, Sauneuf B et al. Predictors of negative first SARS-CoV-2 RT-PCR despite final diagnosis of COVID-19 and association with outcome. Sci Rep. 2021 Jan 27;11(1):2388. doi: 10.1038/s41598-021-82192-6
Toplam 11 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Klinik Tıp Bilimleri
Bölüm Araştırma Makalesi
Yazarlar

Murathan Köksal Bu kişi benim 0000-0002-5936-2925

Erdem Özkan Bu kişi benim 0000-0001-8120-7051

Elmas Uysal Bu kişi benim 0000-0003-0257-2443

Handan Ankaralı Bu kişi benim 0000-0002-3613-0523

Işıl Özkoçak Turan Özkoçak Turan Bu kişi benim 0000-0002-0405-0107

Adalet Aypak Aypak Bu kişi benim 0000-0001-8850-2475

Yayımlanma Tarihi 31 Ağustos 2022
Yayımlandığı Sayı Yıl 2022 Cilt: 12 Sayı: 2

Kaynak Göster

APA Köksal, M., Özkan, E., Uysal, E., Ankaralı, H., vd. (2022). Comparing The Computed Tomography Findings Of The Covid-19 PCR Positive Patients in Intensive Care Unit and PCR Negative Suspected Patients in Terms of Clinical and Laboratory Data. Kafkas Journal of Medical Sciences, 12(2), 127-134.
AMA Köksal M, Özkan E, Uysal E, Ankaralı H, Özkoçak Turan IÖT, Aypak AA. Comparing The Computed Tomography Findings Of The Covid-19 PCR Positive Patients in Intensive Care Unit and PCR Negative Suspected Patients in Terms of Clinical and Laboratory Data. KAFKAS TIP BİL DERG. Ağustos 2022;12(2):127-134.
Chicago Köksal, Murathan, Erdem Özkan, Elmas Uysal, Handan Ankaralı, Işıl Özkoçak Turan Özkoçak Turan, ve Adalet Aypak Aypak. “Comparing The Computed Tomography Findings Of The Covid-19 PCR Positive Patients in Intensive Care Unit and PCR Negative Suspected Patients in Terms of Clinical and Laboratory Data”. Kafkas Journal of Medical Sciences 12, sy. 2 (Ağustos 2022): 127-34.
EndNote Köksal M, Özkan E, Uysal E, Ankaralı H, Özkoçak Turan IÖT, Aypak AA (01 Ağustos 2022) Comparing The Computed Tomography Findings Of The Covid-19 PCR Positive Patients in Intensive Care Unit and PCR Negative Suspected Patients in Terms of Clinical and Laboratory Data. Kafkas Journal of Medical Sciences 12 2 127–134.
IEEE M. Köksal, E. Özkan, E. Uysal, H. Ankaralı, I. Ö. T. Özkoçak Turan, ve A. A. Aypak, “Comparing The Computed Tomography Findings Of The Covid-19 PCR Positive Patients in Intensive Care Unit and PCR Negative Suspected Patients in Terms of Clinical and Laboratory Data”, KAFKAS TIP BİL DERG, c. 12, sy. 2, ss. 127–134, 2022.
ISNAD Köksal, Murathan vd. “Comparing The Computed Tomography Findings Of The Covid-19 PCR Positive Patients in Intensive Care Unit and PCR Negative Suspected Patients in Terms of Clinical and Laboratory Data”. Kafkas Journal of Medical Sciences 12/2 (Ağustos 2022), 127-134.
JAMA Köksal M, Özkan E, Uysal E, Ankaralı H, Özkoçak Turan IÖT, Aypak AA. Comparing The Computed Tomography Findings Of The Covid-19 PCR Positive Patients in Intensive Care Unit and PCR Negative Suspected Patients in Terms of Clinical and Laboratory Data. KAFKAS TIP BİL DERG. 2022;12:127–134.
MLA Köksal, Murathan vd. “Comparing The Computed Tomography Findings Of The Covid-19 PCR Positive Patients in Intensive Care Unit and PCR Negative Suspected Patients in Terms of Clinical and Laboratory Data”. Kafkas Journal of Medical Sciences, c. 12, sy. 2, 2022, ss. 127-34.
Vancouver Köksal M, Özkan E, Uysal E, Ankaralı H, Özkoçak Turan IÖT, Aypak AA. Comparing The Computed Tomography Findings Of The Covid-19 PCR Positive Patients in Intensive Care Unit and PCR Negative Suspected Patients in Terms of Clinical and Laboratory Data. KAFKAS TIP BİL DERG. 2022;12(2):127-34.