Assessment of the Relationship Between Serum Albumin to Creatinine Ratio and Long-Term Mortality in Patients with ST-Segment Elevation Myocardial Infarction

Yıl 2023, Cilt: 13 Sayı: 2, 166 - 172, 25.08.2023

İnanç Artaç , Timor Omar Muammer Karakayalı Doğan İliş Öztürk Demir Mehmet Hakan Şahin Yavuz Karabağ İbrahim Rencüzoğulları

Öz

Aim: In recent years, an increasing number of evidence suggests
that the inflammation plays a significant role in the pathophysiology of ST-segment elevation myocardial infarction (STEMI). The
association between inflammatory markers and renal functions in
STEMI prognosis has been previously reported. No studies have
investigated the ability of the serum albumin to creatinine ratio
(sACR), defined as a prognostic score, to predict long term mortality in patients experiencing STEMI.
Material and Method: This retrospective study included 1133 patients experiencing STEMI. The study population was divided into
two groups according to survival and analyzed whether the sACR
was an independent predictor of long-term mortality.
Results: Out of 1133 patients, death was observed in 112 patients
(9%) an average follow-up of 55 months. During the total follow-up
period, patients were divided into two groups according to survival. Compared to the survival group, long-term mortality group
was older, had a higher SYNTAX score and a lower sACR (p<0.05).
Independent predictors of long-term mortality were found to be
age, smoking, LVEF, and sACR (HR: 0.627 95% CI: 0.533–0.737;
p<0.001). Receiver operating characteristic (ROC) curve comparisons for long-term mortality demonstrated that the sACR was a
better predictor than both albumin and creatinine, separately.
Conclusion: The present study revealed that sACR is an independent predictor of long-term mortality in patients experiencing
STEMI. As a marker which can be easily obtained and calculated,
sACR can be an effective parameter used for prognosis estimation
of STEMI.

Anahtar Kelimeler

serum albumin, creatinine, sACR; mortality, ST-segment elevation myocardial infarction

Kaynakça

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