Comparison of Corneal Endothelial Parameters and Intraocular Pressure Alterations After Uneventful Cataract Surgery with 1.8% and 3% Sodium Hyaluronate

Yıl 2024, Cilt: 14 Sayı: 1, 87 - 93, 30.04.2024

Emre Aydın Hasan Akgöz Mehmet Gökhan Aslan

Öz

Aim: To assess the effectiveness and safety of two recently developed sodium hyaluronate (Na-Hy) items, differentiated by concentrations of 1.8% and 3%.
Material and Method: Fifty-nine uneventful phacoemulsification cataract surgeries were retrospectively evaluated. Patients were separated into two groups according to the ocular viscoelastic device (OVD) used in the capsulorhexis and phacoemulsification steps of the surgery. There were 30 patients in the 3% Na-Hy group and 29 patients in the 1.8% Na-Hy group. Patients were evaluated regarding endothelial changes by specular microscopy and postoperative intraocular pressure (IOP) alterations. Patients with systemic diseases, intraoperative complications, or mature cataracts were excluded.
Results: The two groups had no significant difference in demographic characteristics. Mean phaco time was 10.8±3.58 seconds in the 3% Na-Hy group and 10.55±3.85 seconds in the 1.8% Na- Hy group. The preoperative, postoperative 1st, and 3rd months endothelial cell density (ECD) measurements were 2525.8±219.7, 2304.7±197.6 and 2230.6±208.8 cells/mm2 in the 3% Na-Hy group, and 2549.7±222.4, 2256.6±198.4 and 2166.3±201.5 cells/ mm2 in the 1.8% Na-Hy group, respectively. The preoperative, postoperative 1st day and 1st week IOP measurements were 17.1±2.56, 20.5±3.82 and 15.76±2.19 in 3% Na-Hy group and 15.96±2.56, 18.1±3.35 and 14.93±2.15 in 1.8% Na-Hy group, respectively. The reduction in endothelial cell density was notably greater in the group treated with 1.8% Na-Hy. At the same time, no significant differences were observed among the groups regarding changes in postoperative intraocular pressure (IOP).
Conclusion: Both Na-Hy products seem safe and effective for routine cataract cases. The 3% Na-Hy showed a better performance for corneal endothelium protection while causing minimal IOP elevation.

Anahtar Kelimeler

Hyotek, ocular viscoelastic device, phacoemulsification, sodiumhyaluronate

Kaynakça

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