Adli Analizde Malathion ve 4F-MDMB-BUTICA'nın Eşzamanlı Tanımlanması için GC-MS Uygulaması

Öz

Sentetik kannabinoidler, doğal esrarın (THC) etkilerini taklit etmek üzere geliştirilmiş kimyasallar olup, THC’den çok daha güçlü ve tehlikelidirler. Bu tip maddeler “bonzai” gibi isimler ile bilinen bitkisel karışımlara püskürtülerek yasa dışı uyuşturucu pazarına sürülür. Malathion, tarımda zararlıların yok edilmesi ve kontrolü için kullanılan organofosforlu (OP) bir insektisittir. İnsanlar için düşük toksisitede bile malathiona maruz kalmanın solunum yolları ve sinir sistemi üzerinde olumsuz etkileri vardır. Bu çalışmada, sedatif etkiye sahip sentetik kannabinoidler ile birlikte kullanılan tarım ilacı kalıntılarının numunelerde eş zamanlı tespit edilmesine yönelik bir GC-MS metodu geliştirilmiştir. Organofosfatlı insektisitlerden Malathion ve yeni nesil sentetik kannabinoidlerden 4-Fluoro-MDMB-BUTICA, bitkisel numuneler üzerinde kalitatif olarak analiz edilmiştir. Elde edilen veriler neticesinde sedatif etkide bitkisel otların içerisine emdirilen Malathion tarım ilacı tespit edilerek analizine olanak sağlanacaktır. Bu çalışmada tarım ilaçlarının kalitatif analizi, Gaz Kromatografi-Kütle Spektrometresi (GC-MS) cihazı ile optimize edilen deney metodu kullanılarak yapılmıştır.

Anahtar Kelimeler

• Malathion
• kanabinoid
• Adli Analiz
• GC-MS

Application of GC-MS for Simultaneous Identification of Malathion and 4F-MDMB-BUTICA in Forensic Analysis

Öz

Synthetic cannabinoids are chemicals developed to mimic the effects of natural marijuana (THC), and they are much more powerful and dangerous than THC. These types of substances are sprayed into herbal mixtures known as "bonzai" and put into the illegal drug market. Malathion is an organophosphorus (OP) insecticide used for the destruction and control of pests in agriculture. Even with low toxicity to humans, exposure to malathion has adverse effects on the respiratory tract and nervous system. In this study, a GC-MS method was developed for the simultaneous detection of pesticide residues used with synthetic cannabinoids with sedative effects in samples. Malathion, an organophosphate insecticide, and 4-Fluoro-MDMB-BUTICA, a new generation synthetic cannabinoid, were qualitatively analyzed on plant samples. As a result of the data obtained, Malathion pesticide, which has a sedative effect and is absorbed into herbs, will be detected and analyzed. In this study, qualitative analysis of pesticides was performed using the experimental method optimized with the Gas Chromatography-Mass Spectrometry (GC-MS) device.

Anahtar Kelimeler

• Malathion
• Cannabinoid
• Forensic Analysis
• GC-MS

Kaynakça

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