Chemical Composition, Antibacterial and Antioxidant Activities of Thymus Praecox

İzzet Şener; Fulya Tekelioğlu; Merve Zurnacı; Pınar Baloglu; Mahmut Gür; Kerim Güney

doi:10.17475/kastorman.908659

TR EN

Thymus Praecox’un Kimyasal Bileşimi, Antibakteriyel ve Antioksidan Aktiviteleri

Öz

Çalışmanın amacı: Kastamonu bölgesinden toplanan Thymus praecox'un kimyasal bileşimini, antioksidan kapasitesini ve antibakteriyel aktivitesini belirlemektir. Materyal ve yöntem: Kimyasal bileşimin belirlenmesinde spektroskopik ve kromatografik analizler uygulandı. Kekik özleri beş farklı çözücü kullanılarak hazırlandı. HPLC kullanılarak Thymus praecox içeriğinde bulunan flavonoidlerin varlığı ve GC-MS kullanılarak uçucu yağın kimyasal içeriği araştırıldı. Kekiğin yaprak ve sapındaki mineral analizleri ICP-OES ile belirlendi. Antioksidan kapasite, DPPH serbest radikal temizleme yöntemi ve H2O2 süpürme yöntemi gibi iki yöntem kullanılarak belirlendi. On bakteri, Gram (+) ve Gram (-) üzerindeki antibakteriyel aktivite disk difüzyon yöntemi kullanılarak test edildi. Temel sonuçlar: Deneysel sonuçlar, kekik ekstraktlarının bazı bakterilere karşı antibakteriyel aktiviteye sahip olduğunu göstermiştir. Sonuç olarak, en çok etkilenen bakterinin S. aureus olduğu bulundu. İnhibisyon zon çapının 8-12 mm arasında olduğu belirlendi. Çözücülerin antibakteriyel aktivite, antioksidan kapasite, toplam fenolik ve toplam flavonoid miktarları üzerine etkisi gözlendi. Araştırma vurguları: Çalışmalar T. praecox'un doğal bir antimikrobiyal ve antioksidan ajan olarak kullanılma potansiyeline sahip olduğunu ve doğal bir destek tedavisi olarak kullanılabileceğini gösterdi.

Anahtar Kelimeler

Thymus praecox, Uçucu yağ, Antibakterial, Antioxidant, Fenolic, Flavonoid, HPLC, GC-MS, ICP-OES

Proje Numarası

KUBAP-03/ 2017-14

Chemical Composition, Antibacterial and Antioxidant Activities of Thymus Praecox

Öz

Aim of Study: It was aimed to determine the chemical composition, antioxidant and antibacterial activity of the Thymus praecox which distributed in the Kastamonu region. Material and methods: Spectroscopic and chromotographic analysis were applied in the determination of the chemical composition. Thyme extracts were prepared using five different solvents. In Thymus praecox, the presence of flavonoids using HPLC and the chemical content of essential oil using GC-MS were investigated. The analyses of the mineral were determined in leaf and stem of thyme by ICP-OES. Antioxidant capacity was determined using two methods such as DPPH free radical scavenging and H2O2 scavenging. Antibacterial activity on ten bacteria, Gram (+) and Gram (-) was tested using the disc diffusion method. Main results: Experimental results showed that thyme extracts have antibacterial activities against some bacteria. As a result, it was found that the most affected bacteria was S. aureus. Inhibition zone diameter was determined to be between 8-12 mm. The effect of solvent on antibacterial activity, antioxidant capacity, total phenolic and total flavonoid amounts were observed. Highlights: These results showed that T. praecox has the potential to be used as a natural antimicrobial and antioxidant agent, and can be used as a natural supportive treatment.

Anahtar Kelimeler

Thymus praecox, Essential oil, Antibacterial, Antioxidant, Phenolic, Flavonoid, HPLC, GC-MS, ICP-OES

Destekleyen Kurum

Kastamonu University, Scientific Research Projects Coordination Department.

Proje Numarası

KUBAP-03/ 2017-14

Kaynakça

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Ayrıntılar

Birincil Dil

İngilizce

Konular

-

Bölüm

Araştırma Makalesi

Yazarlar

İzzet Şener ^* Bu kişi benim
0000-0003-0540-7523
Türkiye

Fulya Tekelioğlu Bu kişi benim
0000-0002-6728-0452
Türkiye

Merve Zurnacı Bu kişi benim
0000-0002-2928-3492
Türkiye

Pınar Baloglu Bu kişi benim
0000-0002-1575-8071
Türkiye

Mahmut Gür Bu kişi benim
0000-0001-9942-6324
Türkiye

Kerim Güney Bu kişi benim
0000-0003-2305-790X
Türkiye

Yayımlanma Tarihi

3 Nisan 2021

Gönderilme Tarihi

11 Kasım 2020

Kabul Tarihi

17 Mart 2021

Yayımlandığı Sayı

Yıl 2021 Cilt: 21 Sayı: 1

DOI

https://doi.org/10.17475/kastorman.908659

IZ

https://izlik.org/JA25GZ33FB

APA

Şener, İ., Tekelioğlu, F., Zurnacı, M., Baloglu, P., Gür, M., & Güney, K. (2021). Chemical Composition, Antibacterial and Antioxidant Activities of Thymus Praecox. Kastamonu University Journal of Forestry Faculty, 21(1), 65-73. https://doi.org/10.17475/kastorman.908659

AMA

1.Şener İ, Tekelioğlu F, Zurnacı M, Baloglu P, Gür M, Güney K. Chemical Composition, Antibacterial and Antioxidant Activities of Thymus Praecox. Kastamonu University Journal of Forestry Faculty. 2021;21(1):65-73. doi:10.17475/kastorman.908659

Chicago

Şener, İzzet, Fulya Tekelioğlu, Merve Zurnacı, Pınar Baloglu, Mahmut Gür, ve Kerim Güney. 2021. “Chemical Composition, Antibacterial and Antioxidant Activities of Thymus Praecox”. Kastamonu University Journal of Forestry Faculty 21 (1): 65-73. https://doi.org/10.17475/kastorman.908659.

EndNote

Şener İ, Tekelioğlu F, Zurnacı M, Baloglu P, Gür M, Güney K (01 Nisan 2021) Chemical Composition, Antibacterial and Antioxidant Activities of Thymus Praecox. Kastamonu University Journal of Forestry Faculty 21 1 65–73.

IEEE

[1]İ. Şener, F. Tekelioğlu, M. Zurnacı, P. Baloglu, M. Gür, ve K. Güney, “Chemical Composition, Antibacterial and Antioxidant Activities of Thymus Praecox”, Kastamonu University Journal of Forestry Faculty, c. 21, sy 1, ss. 65–73, Nis. 2021, doi: 10.17475/kastorman.908659.

ISNAD

Şener, İzzet - Tekelioğlu, Fulya - Zurnacı, Merve - Baloglu, Pınar - Gür, Mahmut - Güney, Kerim. “Chemical Composition, Antibacterial and Antioxidant Activities of Thymus Praecox”. Kastamonu University Journal of Forestry Faculty 21/1 (01 Nisan 2021): 65-73. https://doi.org/10.17475/kastorman.908659.

JAMA

1.Şener İ, Tekelioğlu F, Zurnacı M, Baloglu P, Gür M, Güney K. Chemical Composition, Antibacterial and Antioxidant Activities of Thymus Praecox. Kastamonu University Journal of Forestry Faculty. 2021;21:65–73.

MLA

Şener, İzzet, vd. “Chemical Composition, Antibacterial and Antioxidant Activities of Thymus Praecox”. Kastamonu University Journal of Forestry Faculty, c. 21, sy 1, Nisan 2021, ss. 65-73, doi:10.17475/kastorman.908659.

Vancouver

1.İzzet Şener, Fulya Tekelioğlu, Merve Zurnacı, Pınar Baloglu, Mahmut Gür, Kerim Güney. Chemical Composition, Antibacterial and Antioxidant Activities of Thymus Praecox. Kastamonu University Journal of Forestry Faculty. 01 Nisan 2021;21(1):65-73. doi:10.17475/kastorman.908659

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Volatile Oil Yield and Composition, Total Phenolic Content, Antioxidant Activity and Secondary Metabolite Content of Collected Thymus praecox Species in Rize

Chemistry & Biodiversity

https://doi.org/10.1002/cbdv.202300180

Chemical Composition, Antibacterial and Antioxidant Activities of Thymus Praecox

Thymus Praecox’un Kimyasal Bileşimi, Antibakteriyel ve Antioksidan Aktiviteleri

Öz

Anahtar Kelimeler

Proje Numarası

Chemical Composition, Antibacterial and Antioxidant Activities of Thymus Praecox

Öz

Anahtar Kelimeler

Destekleyen Kurum

Proje Numarası

Kaynakça

Ayrıntılar

Birincil Dil

Konular

Bölüm

Yazarlar

Yayımlanma Tarihi

Gönderilme Tarihi

Kabul Tarihi

Yayımlandığı Sayı

DOI

IZ

Kaynak Göster

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