Hypnum andoi A.J.E. Sm.’nin in vitro Antimikrobiyal Etki Taraması

Yıl 2012, Cilt: 12 Sayı: 1, 97 - 101, 01.03.2012

Ergin Murat Altuner Kerem Canlı

Öz

Anahtar Kelimeler

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In vitro Antimicrobial Screening of Hypnum andoi A.J.E. Sm

Öz

Anti-infektif ilâçların kullanımındaki büyük artış, mikrobiyal evrim ve antibiyotik direncin ana sebebi olarak gösterilmektedir. Bu sebeple, halk sağlığının geleceği için yeni alternatif antibiyotik ve antifungalların keşfedilmesi büyük önem taşımaktadır. Bu çalışmanın amacı, Hypnum andoi A.J.E. Sm. etanol ekstraktlarının Bacillus subtilis ATCC 6633, Candida albicans ATCC 10231, Enterobacter aerogenes ATCC13048, Enterococcus durans, Enterococcus faecalis ATCC 29212, Enterococcus faecium, Escherichia coli ATCC 25922, Escherichia coli CFAI, Klebsiella pneumoniae, Listeria monocytogenes ATCC 7644, Salmonella enteritidis ATCC 13075, Salmonella infantis, Salmonella kentucky, Salmonella typhimurium SL 1344, Staphylococcus aureus ATCC 25923, Staphylococcus carnosus MC1.B, Staphylococcus epidermidis DSMZ 20044 ve Streptococcus agalactiae DSMZ 6784 olmak üzere 17 bakteri ve 1 mantar suşuna karşı in vitro antimikrobiyal etkisinin disk difüzyon yöntemi kullanılarak belirlenmesidir. Sonuç olarak, H. andoi ekstraktlarının C. albicans, E. aerogenes, E. coli, K. pneumonia, S. carnosus ve S. kentucky gibi bazı gram pozitif ve gram negatif mikroorganizmaya etki gösterdiği gözlenmiştir

Anahtar Kelimeler

Hypnum andoi, antimikrobiyal aktivite, antimikrobiyal tarama, etanol ekstraktı

Kaynakça

• Altuner E.M., Akata I. 2010 Antimicrobial Activity of Some Macrofungi Extracts. Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 14, 45-49.
• Altuner E.M., Çeter T., İşlek C. 2010. Investigation of antifungal activity of Ononis spinosa L. ash used for the therapy of skin infections as folk remedies. Mikrobiyoloji Bülteni, 44, 633-639.
• Altuner E.M., Çetin B. 2009. Antimicrobial activity of Thuidium delicatulum (Bryopsida) extracts. Kafkas Üniversitesi, Fen Bilimleri Enstitüsü Dergisi, 2, 85-92.
• Altuner E.M., Çetin B. 2010. Antimicrobial activity of Tortella tortulosa (Hedw.) Limpr. Extracts. Kastamonu University, Journal of Forestry, 10, 111-116.
• Andrews J.M. 2003. BSAC standardized disc susceptibility testing method (version 6). Journal of Antimicrobial Chemotherapy, 60, 20-41.
• Baytop T. 1999. Geçmişte ve Bugün Türkiye’de Bitkiler ile Tedavi. Nobel Tıp Kitabevi Ltd Şti. İstanbul.
• Clardy J., Walsh C. 2004. Lessons from natural molecules. Nature, 432, 829-837.
• Collard J.M., Place S., Denis O., Rodriguez- Villalobos H., Vrints M., Weill F.X., Baucheron S., Cloeckaert A., Struelens M., Bertrand S. 2007. Travel-acquired salmonellosis due to Salmonella Kentucky resistant to ciprofloxacin, ceftriaxone and co-trimoxazole and associated with treatment failure. J. Antimicrob. Chemother., 60, 190-192.
• Cos P. Vlietinck, A.J., Vanden Berghe D., Maes L. 2006. Anti-infective potential of natural products: How to develop a stronger in vitro ‘proof-of-concept’. Ethnopharmacology, 106, 290-302. Journal of Enfert C., Hube B. 2007. Candida:
• Comparative and Functional Genomics. Caister Academic Press.
• Hammer K.A., Carson C.F., Riley, T.V. 1999. Antimicrobial activity of essential oils and other plant extracts. Journal of Applied Microbiology, 86, 985 - 990.
• Jones F.A. 1996. Herbs - useful plants. Their role in history and today. European Journal of Gastroenterology and Hepatology, 8, 1227-1231.
• Keleş O., Ak S., Bakırel T., Alpınar K. 2001. Türkiye’de yetişen bazı bitkilerin antibakteriyel etkisinin Veterinary and Animal Sciences, 25:559-565. Turkish Journal of
• Mahasneh A.M. and El-Oqlah A.A. 1999. Antimicrobial activity of extracts of herbal plants used in the traditional medicine of Jordan. Journal of Ethnopharmacology, 64, 271-276.
• Nikaido H. 1998. Antibiotic resistance caused by gram-negative multidrug efflux pumps. Clinical Infectious Diseases, 27, 32-41.
• Okeke I.N., Laxmaninarayan R., Bhutta Z.A., Duse A.G., Jenkins P., O’Brien T.F., Pablos- Mendez A., Klugman, K.P. 2005. Antimicrobial resistance in developing countries. Part 1: recent trends and current status. Lancet Infectious Diseases, 5, 481-493.
• Paudel B., Bhattarai H.D., Lee J.S., Hong S.G., Shin H.W., Yim, J.H. 2008. Antibacterial Potential of Antarctic Lichens against Human Pathogenic Phytotheraphy Research, 22, 1269-1271. Bacteria.
• Ryan K.J., Ray C.G. 2004. Sherris Medical Microbiology (4th ed.). McGraw Hill.
• Silici S., Koc, A.N. 2006. Comparative study of in vitro methods to analyse the antifungal activity of propolis against yeasts isolated from patients with superficial mycoses. Letters in Applied Microbiology, 43, 318-324.
• Syed G.W., Syed A.S., Oh L.A. 2010. Risk Evaluation Under Various Speculations of Antibiotic Usage; A Cohort Survey Among Outpatients of Pinang, Malaysia. Eur J Gen Med, 7, 303-309. URL1. 2007. WHO (World Health Organization), The world health report 2007: A safer future: global public health security in the 21st century, 2007, http://www.who.int/whr/2007 [Accessed 01 January 2012].
• URL2. 2007. Fraser S.L., Arnett M., Sinave C.P. Enterobacter infections, Available from: http://www.emedicine.com/med/topic678.htm [Accessed 01 January 2012].
• URL3. 2011. Sintchenko V. Salmonella Kentucky: stopping the spread of a new superbug, http://theconversation.edu.au/salmonella- kentucky-stopping-the-spread-of-a-new- superbug-2878 [Accessed 25 January 2012].
• URL4. 2006. Enter-net. Quarterly Salmonella Report http://www.ecdc.europa.eu/en/publications/Public ations/0611_SUR_Enter- 2006/3.