Chemical Compounds and Biological Activity of Turkish Santolina chamaecyparissus L. Essential Oil by Microwave Assisted Distillation

Yıl 2021, Cilt: 21 Sayı: 2, 165 - 175, 30.09.2021

Özge Süfer Ahmet Ceylan Dilşad Onbaşılı Gökçen Çelik Yuvalı Fuat Bozok

https://doi.org/10.17475/kastorman.1000463

Öz

Aim of study: The essential oil of S. chamaecyparissus (SEO) was isolated by microwave assisted distillation system to analyze the antioxidant and antimicrobial activities.
Area of study: S. chamaecyparissus were collected from Osmaniye province of Turkey in April 2018.
Material and method: The chemical constituents and groups (by GC/MS and FTIR spectroscopy, respectively), antioxidant (by DPPH technique) and antimicrobial activities (by agar disc diffusion method) of SEO were investigated.
Main results: Twenty aromatic compounds were determined and artemisia ketone (39.83%), camphor (17.65%), β-phellandrene (8.03%) and β-bisabolene (7.32%) were the most abundant. IC50 values which were the indicators of antioxidant behavior of SEO, butylated hydroxytoluene (BHT) and gallic acid recorded as 88.301, 0.212 and 0.021 g/L respectively. The antimicrobial activity results showed that all tested microorganisms (Escherichia coli, Streptococcus mutans, Bacillus cereus, Bacillus subtilis, Candida albicans) were highly inhibited.
Highlights: SEO could be a good source of monoterpenes especially artemisia ketone. Its herbaceous fragrance may provide a new usage area in men’s perfumery.

Anahtar Kelimeler

Santolina chamaecyparissus, Essential Oil, Antioxidant and Antimicrobial Activity

Mikrodalga Destekli Destilasyon ile Elde Edilen Türk Santolina chamaecyparissus L. Uçucu Yağının Kimyasal Bileşikleri ve Biyolojik Aktivitesi

Öz

Çalışmanın amacı: S. chamaecyparissus uçucu yağı (SUY), antioksidan ve antimikrobiyal aktivitelerini belirlemek amacıyla izole edilmiştir.
Çalışma alanı: S. chamaecyparissus Türkiye’nin Osmaniye ilinden, Nisan 2018’de toplanmıştır.
Materyal ve yöntem: SUY’nin kimyasal bileşenleri ve grupları (sırasıyla gaz kromatografisi/kütle spektrometresi (GC/MS) ve Fourier dönüşümlü kızılötesi spektroskopisi (FTIR) yoluyla), antioksidan aktivitesi (DPPH yöntemiyle) ve antimikrobiyal aktivitesi (agar disk difüzyon tekniğiyle) araştırılmıştır.
Temel sonuçlar: Yirmi aromatik bileşen tespit edilmiş olup, artemisia keton (%39.83), kamphor (%17.65), β-phellandren (%8.03) ve β-bisabolen (%7.32) uçucu yağda miktarı en fazla olanlardır. Antioksidan davranışın bir ölçüsü olan IC50 değeri yağda, bütil hidroksitoluende (BHT) ve gallik asitte sırasıyla 88.301, 0.212 ve 0.021 g/L olarak hesaplanmıştır. Antimikrobiyal bulguları da, tüm test edilen mikroorganizmaların (Escherichia coli, Streptococcus mutans, Bacillus cereus, Bacillus subtilis, Candida albicans) SUY’da yüksek oranda inhibe olduğunu göstermiştir.
Araştırma vurguları: SUY, özellikle artemisia keton olmak üzere, monoterpenlerin iyi bir kaynağı olabilir. Yağın otsu kokusu, erkek parfümlerinde bu yağın yeni bir kullanım alanını açığa çıkartabilir.

Anahtar Kelimeler

Santolina chamaecyparissus, Esansiyel Yağ, Antioksidan ve Antimikrobiyal Aktivite

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