A Preliminary Phytochemical, Pharmacognostic and Physicochemical Evaluation of Endemic Thymus spathulifolius (Lamiaceae)

Yıl 2023, Cilt: 23 Sayı: 1, 11 - 21, 24.03.2023

Nuraniye Eruygur Yurdanur Akyol Mehmet Tekin

https://doi.org/10.17475/kastorman.1269478

Öz

Aim of study: The members of the genus Thymus are widely used in Turkey as herbal teas, spices and salads for different purpose and the herbs of Thymus spathulifolius are reported to have medicinal value. Therefore, in this study various pharmacognostic parameters, physicochemical properties and anatomical characters of Thymus spathulifolius Hausskn. & Velen., is a medicinal plant and endemic to Turkey, were investigated.
Area of study: T. spathulifolius was dried and stored according to herbarium techniques in the Herbarium of Pharmacy Faculty, Trakya University, collected from Sivas, Turkey.
Material and methods: The total ash, moisture content, and physicochemical tests on the different extracts obtained from the endemic T. spathulifolius aerial parts collected from Sivas province were determined according to the World Health Organization (WHO) standards for crude drugs.
Main results: The moisture content and total ash amount of the drug obtained from this plant is in accordance with the WHO standards. Phytochemical screening for secondary metabolites showed the presence of carbohydrates, antraquinone glycosides, steroids, flavonoids and coumarins, while other phytochemicals such as alkaloids and saponins were absent. Besides, the cross-sections of root, stem and leaf were examined and detailed. The total ash value was found as 7.36 ± 0.21% and acid insoluble ash was 0.14 ± 0.72%.
Highlights: The present study provided important information for correct authentication and standardization of this plant material.

Anahtar Kelimeler

Thymus spathulifolius, Phytochemical, Microscopic, Physicochemical Parameters

Destekleyen Kurum

Sivas Cumhuriyet University scientific research project coordinator

Proje Numarası

ECZ-020

Endemik Thymus spatulifolius (Lamiaceae) 'un Ön Fitokimyasal, Farmakognostik ve Fizikokimyasal Açıdan Değerlendirilmesi

Öz

Çalışmanın amacı: Thymus cinsi üyeleri Turkiye’de bitkisel çay, baharat ve salata olarak farklı amaçlarla yaygın kullanılmaktadır. Bu çalışmada, Türkiye’ye endemik olan ve tıbbi değeri olan Thymus spathulifolius Hausskn. & Velen bitkisi farmakognozik parametreler, fizikokimyasal ve anatomik özellikleri açısından incelenmiştir.
Çalışma alanı: Thymus spathulifolius Türkiye'nin Sivas ilinden toplanmış ve herbaryum tekniklerine göre kurutularak Trakya Üniversitesi Eczacılık Fakültesi Herbaryumunda saklanmıştır.
Materyal ve yöntem: Sivas bölgesinden toplanan endemik T. spathulifolius türünün toprak üstü ksıımlarından total kül ve nem tayini ve hazırlanan farklı ekstreler üzerinde fizikokimyasal testler droglar için olan WHO standartlarına göre yapılmıştır.
Temel sonuçlar: Bu bitkiden elde edilen drogun nem miktarı ve total kül miktarı Dünya Sağlık Örgütü (DSÖ) standartlarına uygundur. Sekonder metabolitlerden fitokimyasal tarama sonucu karbonhidratlar, antrakinon glikozitleri, steroitler, flavonoitler ve kumarin içerdiği, alkaloit ve saponin gibi fitokimyasallarca yoksun olduğu tespit edilmiştir. Ayrıca kök, gövde ve yaprak enine kesitleri anatomik olarak incelenmiş ve detayları ortaya çıkarılmıştır. Total kül miktarı %7.36 ± 0.21, asitte çözünmeyen kül miktarı ise %0.14 ± 0.72 olarak bulunmuştur.
Araştırma vurguları: Bu çalışma T. spathulifolius türünün doğru tanınması ve standardizayonu için önemli bilgiler ortaya koymuş ve yakın türlerle ilgili çalışmalara kaynak oluşturmuştur.

Anahtar Kelimeler

Thymus spathulifolius, Fitokimyasal, Mikroskobik, Fizikokimyasal Parametreler

Proje Numarası

ECZ-020

Kaynakça

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