Types of Paeonia and Their Use in Phytotherapy

Yıl 2021, , 318 - 327, 15.06.2021

Gülbahar Demirboğa , Yasin Demirboğa , Nusret Özbay

https://doi.org/10.31466/kfbd.835385

Cited By: 3

Öz

Treatment with medicinal herbs dates back to the times before Christ and has been widely used all over the world for years. Today, its importance is increasing day by day and it is widely preferred because it is found more reliable. According to the World Health Organization, 20 thousand plant species are known in modern and traditional medicine. The number of plants used by the cosmetic and botanical industry is not included to the number. It takes many years to recognize a plant and use it in treatment and it is very difficult to protect it. Therefore, it is of great importance to recognize and develop the plants used in phytotherapy in the past. Paeonia L. (Paeoniaceae), known as "peony", is a perennial (geofit) plant with showy and attractive flowers and tubers under the ground. Paeoniaceae family is located in the rich flora of our country and has been used for their many medicinal effects. In this review article, peony species and their use in phytotherapy in Turkey and World were discussed with the studies on the subject.

Anahtar Kelimeler

Paeonia, Peony, Phytotherapy, Geophyte

Paeonia Türleri ve Fitoterapide Kullanımı

Öz

Şifalı bitkilerle tedavi, milattan önceki zamanlara kadar uzanır ve yıllardır tüm dünyada yaygın olarak kullanılmaktadır. Günümüzde önemi gün geçtikçe artmakta ve daha güvenilir bulunduğu için yaygın olarak tercih edilmektedir. Dünya Sağlık Örgütü'ne göre modern ve geleneksel tıpta 20 bin bitki türü biliniyor. Kozmetik ve botanik endüstrisinin kullandığı bitki sayısı rakamlara dahil edilmemiştir. Bir bitkiyi tanımak ve tedavide kullanmak uzun yıllar alır ve onu korumak çok zordur. Bu nedenle geçmişte fitoterapide kullanılan bitkilerin tanınması ve geliştirilmesi büyük önem taşımaktadır. "Şakayık" olarak bilinen Paeonia L. (Paeoniaceae), yer altında gösterişli ve çekici çiçekleri ve yumruları olan çok yıllık (geofit) bir bitkidir. Paeoniaceae familyası, ülkemizin zengin florasında yer almakta ve birçok tıbbi etkisinden dolayı kullanılmaktadır. Bu derleme yazısında şakayık türleri ve Türkiye ve Dünya’daki fitoterapide kullanımları konu ile ilgili çalışmalarla tartışılmıştır

Anahtar Kelimeler

Paeonia, Şakayık, Fitoterapi, Geofit

Kaynakça

• Anonymous. (2018). Determination of the problems encountered in the protection of medicinal and aromatic plant diversity, their production and marketing, and the measures to be taken. https://www.tbmm.gov.tr/develop/owa/genel_kurul.cl_getir?pEid=72598 (Access date: 09.10.2020).
• Anonymous. (2020). https://www.trt.net.tr/vizyondergisi/vizyon-dergisi-nisan-2016/ (Access date:08.10.2020).
• Arıtuluk, Z. C., Ezer, N. (2012). Plants used against diabetes among people. Hacettepe University Faculty of Pharmacy Journal, 32(2), 179-208.
• Avcı, M. (2005). Çeşitlilik ve endemizm açısından Türkiye’nin bitki örtüsü. Coğrafya Dergisi, Sayı 13, 28-55.
• Baytop, T., (1994). Turkish plant names dictionary. Ankara: Atatürk High Institution of Culture, Language and History - Turkish Language Association Publications.
• Bomi LeeYong-Wook ShinEun-Ah BaeSan-Jun HanJoo-Sun KimSam-Sik KangDong-Hyun Kim. (2008). Antiallergic effect of the root of Paeonia lactiflora and its constituents paeoniflorin and paeonol. Archives of Pharmacal Research, 31(4), 445-450.
• Baytop, T. (1999). Türkiye’de Bitkiler ile Tedavi. 2. Baskı. İstanbul: Nobel Tıp Kitabevleri Ltd. Şti. Tayf Ofset Baskı.
• Bisset, N. G., Wichtl, M. (1994). Herbal drugs and phytopharmaceuticals. Stuttgart: Medpharm Scientific Publishers. 566 pages.
• Chen, L.-C., Chen, I.-C., Wang, B.-R. & Shao, C.-H. (2009). Drug-use pattern of Chinese herbal medicines in insomnia: a 4-year survey in Taiwan. Journal of Clinical Pharmacy and Therapeutics, 34, 555-560.Davis, P.H. (1965). Flora of Turkey and the East Aegean Islands. Vol. 1, Edinburgh: University Press.
• Davis, P.H. (1965). Flora of Turkey and the east Aegean islands. Vol. 1, Edinburgh: University Press.
• Ding, H. Y., Lin, H. C., Teng, C. M., Wu, Y. C. (2000). Phytochemical and pharmacological studies on Chinese Paeonia species. Journal of the Chinese Chemical Society, 47(2), 381–388.
• Doğan, A. (2008). Ovacık (Tunceli) yöresinin geleneksel halk ilacı olarak kullanılan bitkileri. Yüksek Lisans Tezi, Marmara Üniversitesi, Eczacılık Fakültesi Farmasötik Botanik Anabilim Dalı. İstanbul.
• Donner, J. (2007). Turkey's plant distribution maps. Istanbul: Lazer Ofset Matbaa Tesisleri San. ve Tic. Ltd. Şti.
• Everest, A., Öztürk, E. (2005). Focusing on the ethnobotanical uses of plants in Mersin and Adana provinces (Turkey). Journal of Ethnobiology and Ethnomedicine, 1, 1-6.
• Fakir, H., Korkmaz, M. & Güler, B. (2009). Medicinal plant diversity of Western Mediterrenean Region in Turkey. Journal of Applied Biological Sciences, 3(2), 30-40.
• Friedman, J. M. 2000. Teratology society: presentation to the FDA public meeting on safety issues associated with the use of dietary supplements during pregnancy. Teratology, 62, 134-7.
• Goto, H., Shimada, Y., Akechi, Y., Kohta, K., Hattori, M., and Terasawa, K. (1996). Endothelium-dependent vasodilator effect of extract prepared from the roots of Paeonia lactiflora on isolated rat aorta. Planta Med., 62(5), 436-439.
• He. D. Y., Dai S. M. (2011). Anti-inflammatory and immunomodulatory effects of Paeonia lactiflora Pall., A traditional Chinese herbal medicine. Front Pharmacol. Feb 25; 2: 10. doi: 10.3389 / fphar.2011.00010. PMID: 21687505; PMCID: PMC3108611.
• Halda, J. J., Waddick, J. W. (2004) The Genus Paeonia. (Second Edition). Timber Press, 2010. 227 pages.
• Izzo, A. A, Di Carlo, G, Borrelli, F, Ernst, E. (2005). Cardiovascular pharmacotherapy and herbal medicines: the risk of drug interaction. Int J Cardiol. 98, 1-14.
• Karaman, Ş. & Kocabaş, Y. Z. (2001). Traditional medicinal plants of K. Maras (Turkey). The Sciences, 1(3), 125-128.
• Kaya, E. (2016). Türkiye biyoçeşitliliğinde geofitlerin yeri ve bazı çalışmalar. TÜRKTOB magazine, 18: 69-79.
• Kirby, A. J. and Schmidt R, J. J. (1997). The antioxidant activity of Chinese herbs for eczema and of placebo herbs. Ethnopharmacol., 56, 103-108.
• Koo Y. K., Kim J. M., Koo J. Y., Kang S. S., Bae K, Kim Y. S., Chung J. H., Yun-Choi H. S. (2010). Platelet anti-aggregatory and blood anti-coagulant effects of compounds isolated from Paeonia lactiflora and Paeonia suffruticosa. Pharmazie, 65(8): 624-8.
• Kim, H. J., Chang, E. J., Cho, S. H., Chung, S. K., Park, H. D., Choi, S. W. (2002). Antioxidative activity of resveratrol and its derivatives isolated from seeds of Paeonia lactiflora. Bioscience, Biotechnology, and Biochemistry, 66(9). 1990-1993.
• Karagöz, A., Zencirci, N., Tan, A., Taşkın, T., Köksel, H., Sürek, M., Toker, C. and Özbek, K. 2010. Conservation and use of plant genetic resources. TMMOB Chamber of Agricultural Engineers, Agricultural Engineering 7th Technical Congress, p: 155-177, 11-15 January 2010, Ankara.
• Kaya, E. 2010. Türkiye şakayıklarının (Paeonia Spp.) kültüre alınması ve ıslahı. IV. Süs Bitkileri Kongresi. Erdemli, Mersin. 22-22 Ekim. 2010.
• Lee, S. -J., Lee, H. -K., Jung, M. -K. & Mar, W. (2006). In vitro antiviral activity of 1, 2, 3, 4, 6-penta-O-galloyl-b-D-glucose against hepatitis B virus. Biological & Pharmaceutical Bulletin, 29(10), 2131-2134.
• Mao, Q., Huang, Z., Ip, S., Che, C. (2008). Antidepressant-like effect of ethanol extract from Paeonia lactiflora in Mice. Phytotherapy Research, 22, 1496-1499.
• Mao, Q. -Q., Ip, S. -P., Ko, K. -M., Tsai, S. -H., Xian, Y. -F. & Che, C. -T. (2009). Effects of peony glycosides on mice exposed to chronic unpredictable stress: Further evidence for antidepressant-like activity. Journal of Ethnopharmacology, 124, 316-320.
• Melikoğlu, G., Kurtoğlu, S., and Kültür, Ş. (2015). Plants traditionally used in asthma treatment in Turkey. Marmara Pharmaceutical Journal, 19: 1-11.
• Miyazawa, M., Maruyama, H., Kameoka, H. (1984). Essential oil constituents of “MOUTAN RADIOS CORTEX” Paeonia moutan Sims. (= P. suffruticosa Andrews). Agricultural and Biological Chemistry, 48(11), 2925-2927.
• Nathan M, Scholten R. (1999). The Complete German Commission E Monographs: Therapeutic guide to herbal medicines. Annals of Internal Medicine. 130(5), pp 459.
• Orhan, I., Şener, B., (2005). Discovery of drug candidates from some Turkish plants and conservation of biodiversity. Pure Appl. Chem., 77(1), 53–64.
• Orhan, I., Demirci, B., Omar, I., Siddiqui, H. (2010). Essential oil compositions and antioxidant properties of the roots of twelve Anatolian Paeonia taxa with special reference to chromosome counts. Pharmaceutical Biology, 48(1), 10-16.
• Özhatay, N., Koyuncu, M., (1998). New trends and methods in natural products Research’s, 11-38.
• Picerno, P., Mencherini, T., Sansone, T., Gaudio, P. D., Granata, I., Porta A., Rita P. (2011) Screening of a polar extract of Paeonia rockii: Composition and antioxidant and antifungal activities. Journal of Ethnopharmacology, 138(3), 705-712.
• Sert E, Sert, A, Kalaycı, M. Z., Sakarya, A. A., Yüksel, Ş. B. (2015). The place of phytotherapy in oral and dental health. Integr Medical Derg. 3, 35-40.
• Sarışen Ö, Çalışkan D. (2005). Phytotherapy: attention to treatment with herbs. Sted Magazine, 14/8: 182-7.
• Sener, B. (1994). Recent results in the search for bioactive compounds from Turkish medicinal plants. Pure and Applied Chemistry, 60, 2295-2298.
• Stearn, W. T., Davis, P. H. (1984). Peonies of Greece: A taxonomic and historical survey of the genus Paeonia in Greece. The Goulandris Natural History Museum, Kifissia, Greece; 1st Edition.
• Sevim, D., Senol, F. S., Orhan, I., Şener, B., Kaya, E. (2011). Anti-amnesic activity screening of the seed ethanol extracts of Turkish Paeonia taxa by in vitro methods. Planta Med., 77 - PM166.
• Tosun, G., Kahriman, N., Gulec Colonel, C., Alpay Karaoglu, Ş., Yaylı, N. (2011). Antimicrobial activity and volatile constituents of the flower, leaf, and stem of Paeonia daurica grown in Turkey. Turk J Chem, 35, 145–153.
• Tanker, N., Koyuncu, M. & Coşkun, M. (2007). Farmasötik Botanik. Ankara: Ankara Üniversitesi Eczacılık Fakültesi Yayınları.
• Tuzlacı, E. (2006). Turkey Plant Dictionary. Istanbul: Alfa Publishing Distribution Ltd. Şti.
• Ugulu, I., Baslar, S., Yorek, N. & Doğan, Y. (2009). The investigation and quantitative ethnobotanical evaluation of medicinal plants used around Izmir province, Turkey. Journal of Medicinal Plants Research, 3(5), 345-367.
• Uyanık, M., Kara, M., Gürbüz, B., Özgen, Y. (2013). Türkiye’de bitki çeşitliliği ve endemizm. Ekoloji Sempozyumu, Tekirdağ, 2013. S. 197.
• Ünlü, S., 2010. Türkiye’nin Paeonia L. türleri üzerinde farmasötik botanik araştırmalar. Yüksek Lisans Tezi.
• Verma, R. S., Padalia R. C., Chauhan, A. (2015). Essential oil composition of Himalayan Peony (Paeonia emodi Royle), Journal of Essential Oil Research, 27(6): 477-480.
• Yeşilada, E., Mutlugil, A., Şener, B. (1992). The Antiinflammatory principle of the roots of Paeonia daurica . Int. J. Pharmacognosy, 30(1), 66-70.
• Yeşilada, E., Mutlugil, A., Şener, B. & Sezik, E. (1989). Paeonia daurica Andrews ve P. peregrina Miller’nın antieflamatuar aktivitesi. VIII. Bitkisel İlaç Hammaddeleri Toplantısı (İstanbul, 19-21 Mayıs 1989) Bildiri Kitabı. Cilt II. İstanbul: İ. Ü. Basımevi ve Film Merkezi; 361-364.