Nanomaterial Risk Assesment Review in the Scope of Occupational Health and Safety

Öz

Nanomaterials is engineered materials and there is a growing concern of harmful effects for human health. These concerns have been directed to identify threats, determine risk factors, improve risk assessment methods for occupational health and safety in areas where worker exposure exists. Although there are improvements in sectoral base for nanomaterials and its processes, there isn’t complete regulation or systematic framework containing all risks. It is also not clear how nanomaterials will affect worker’s health in the future. The purpose of this study is to define consize information about risk factors, risk assessments, analysis methods and give a perspective of nanomaterials in context of occupational health and safety.

Anahtar Kelimeler

• Nanotechnology,Nanomaterial,Nanoparticle,Occupational Health and Safety,Risk Management,Risk Assessment,Risk Analysis

İş Sağlığı ve Güvenliği Kapsamında Nanomateryal Risk Değerlendirmesi

Öz

Mühendislik ürünü olan Nanomatereyaller(Nm)’in sağlığa yönelik tehlikeleri konusunda artan bir endişe bulunmaktadır. Bu durum risk grubu altında olan çalışanların Nm’lere maruziyetinin oluşabileceği alanlar ile ilgili mevcut tehlikelerin, risk faktörlerinin tanımlanması, risk değerlendirme methotlarının geliştirilmesi konularında çalışmalara gereksinim olduğunu ortaya çıkarmaktadır. Nanomateryal proseslerle ilgili belirlenmiş bazı standartlar ve sektörel bazda gelişmeler olsada sistematik çerçeve tam anlamıyla oluşmamıştır. Gelişen teknoloji ile  kendisine her geçen gün daha fazla kullanım alanı bulan nanomateryallerin gelecekte insan sağlığına ne gibi zararlar verebileceği araştırılması gereken diğer bir konudur. Bu çalışmada iş sağlığı ve güvenliğinde kapsamında nanomateryallerin özellikleri, risk faktörleri ile nanomateryallerde risk yönetiminde izlenecek risk analiz methodları konusunda perspektif sunabilmek amaçlanmıştır.

Anahtar Kelimeler

• Nanoteknoloji,Nanomateryal,Nanopartikül,İş Sağlığı ve Güvenliği,Risk Yönetimi,Risk Değerlendirmesi,Risk Analizi

Kaynakça

1. 1. Yokel, R. A., & MacPhail, R. C. (2011). Engineered nanomaterials: exposures, hazards, and risk prevention. Journal of Occupational Medicine and Toxicology,, 6:7
2. 2. National Nanotechnology Initiative. (2011). Strategic Plan. National Science and Technology Council, Committee of Technology, Subcommittee on Nanoscale Science, Engineering, and Technology. p.3 [https://www.nano.gov/sites/default/files/pub_resource/2011_strategic_plan.pdf]
3. 3. Jahnel, J., Fleischer, T., & Seitz, S. B. (2013). Risk assessment of nanomaterials and nanoproducts–adaptation of traditional approaches. In Journal of Physics: Conference Series (Vol. 429, No. 1, p. 012063). IOP Publishing.Organic Consumers Association: Groups demand EPA stop sale of 200+ potentially dangerous nano-silver products.1195. [http://www.organicconsumers.org/articles/article_11955.cfm]
4. 4. Group files legalcction for EPA to stop sale of 200 +Nanosilver products, assessment, N. H. nano. 2008 p.6 [https://www.nanowerk.com/nanorisk/pdf/nanoRISK_vol3_iss3.pdf]
5. 5. Kagan, V. E., Shi, J., Feng, W., Shvedova, A. A., & Fadeel, B. (2010). Fantastic voyage and opportunities of engineered nanomaterials: what are the potential risks of occupational exposures? Journal of occupational and environmental medicine, 52(9), 943-946.
6. 6. OECD. List of manufactured nanomaterials and list of endpoints for phase one of the OECD testing programme. OECD Environment, Health and Safety Publications Series on the safety of manufactured nanomaterials No 6. Document ENV/JM/MONO (2008)13. Organization for Economic Coordination and Development. Paris, France; 2008a
7. 7. SCoEaNIHR, E. S. (2009). Risk Assessment of Products of Nanotechnologies. European Commission, Scientific Committee on Emerging and Newly Identified Health Risks (SCENHR): Brussels, Belgium. [http://ec.europa.eu/health/ph_risk/committees/04_scenihr/docs/scenihr_o_023.pdf]
8. 8. Hansen, S. F., Howard, C. V., Martuzzi, M., & Depledge, M. (2013). Nanotechnology and human health: Scientific evidence and risk governance: Report of the WHO expert meeting 10–11 December 2012, Bonn, Germany.[http://www.euro.who.int/__data/assets/pdf_file/0018/233154/e96927.pdf?ua=1]

9. 9. Tsuji, J. S., Maynard, A. D., Howard, P. C., James, J. T., Lam, C. W., Warheit, D. B., & Santamaria, A. B. (2005). Research strategies for safety evaluation of nanomaterials, part IV: risk assessment of nanoparticles. Toxicological sciences, 89(1), 42-50.
10. 10. Development of a web based REACH Toolkit to support the chemical safety assessment of nanomaterials, Guidance on available methods for risk assessment of nanomaterials, Technical Guidances series - 2015
11. 11. Zuin, S., Micheletti, C., Critto, A., Pojana, G., Johnston, H., Stone, V., ... & Marcomini, A. (2011). Weight of evidence approach for the relative hazard ranking of nanomaterials. Nanotoxicology, 5(3), 445-458.
12. 12. Olson, M. S., & Gurian, P. L. (2012). Risk assessment strategies as nanomaterials transition into commercial applications. Journal of Nanoparticle Research, 14(4), 786.
13. 13. Scientific Committee on Emerging and Newly Identified Health Risks. (2012). Opinion on the Memorandum on the use of the scientific literature for human health risk assessment purposes – weighing of evidence and expression of uncertainty.
14. 14. Scientific Committee on Emerging and Newly Identified Health Risks. (2007). Opinion on the appropriateness of the Risk Assessment Methodology in accordance with the technical guidance documents for new and existing substances for assessing the risks of nanomaterials. [http://ec.europa.eu/health/ph_risk/committees/04_scenihr/docs/scenihr_o_010.pdf]
15. 15. EFSA Scientific Committee. (2011). Guidance on the risk assessment of the application of nanoscience and nanotechnologies in the food and feed chain. EFSA Journal, 9(5), 2140.
16. 16. Grieger, K. D., Laurent, A., Miseljic, M., Christensen, F., Baun, A., & Olsen, S. I. (2012). Analysis of current research addressing complementary use of life-cycle assessment and risk assessment for engineered nanomaterials: have lessons been learned from previous experience with chemicals? Journal of Nanoparticle Research, 14(7), 958.
17. 17. Tervonen, T., Linkov, I., Figueira, J. R., Steevens, J., Chappell, M., & Merad, M. (2009). Risk-based classification system of nanomaterials. Journal of Nanoparticle Research, 11(4), 757-766.
18. 18. Warheit, D. B., Webb, T. R., & Reed, K. L. (2003, March). Pulmonary toxicity studies with TiO2 particles containing various commercial coatings. In TOXICOLOGICAL SCIENCES (Vol. 72, pp. 298-298). GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND: OXFORD UNIV PRESS.
19. 19. Unit, R. A. (2004). Nanotechnologies: a preliminary risk analysis on the basis of a Workshop Organized in Brussels on 1-2 March 2004 by the Health and Consumer Protection Directorate General of the European Commission. [http://ec.europa.eu/health/ph_risk/documents/ev_20040301_en.pdf]
20. 20. Arvidsson, R., Furberg, A., & Molander, S. (2016). Review of Screening Risk Assessment Methods for Nanomaterials. Chalmers University of Technology.
21. 21. Geraci, C. L., Lentz, T., & Niemeier, R. (2009). Qualitative risk characterization and management of occupational hazards: control banding (CB); a literature review and critical analysis.
22. 22. Burgman, M. (2005). Risks and decisions for conservation and environmental management. Cambridge University Press.
23. 23. Exposure to Engineered Nanomaterials and Occupational Health and Safety Effects, October 2011 INAIL, Department of Occupational Medicine
24. 24. Vervoort, M. B. H. J. (2012). Risk assessment of occupational used nanomaterials: A comparison of risk assessment methods in order to determine the risk of occupational used nanomaterials in a research environment (Doctoral dissertation, Thesis. Netherland School of Public and Occupational Health).
25. 25. Jensen, K. A., Saber, A. T., Kristensen, H. V., Liguori, B., Jensen, A. Ø., Koponen, I. K., & Wallin, H. (2014). NanoSafer vs. 1.1 Nanomaterial risk assessment using first order modeling. In Topical Scientific Workshop on Regulatory Challenges in Risk Assessment of Nanomaterials.
26. 26. Fleury, D., Fayet, G., Vignes, A., Henry, F., & Frejafon, E. (2013, May). Nanomaterials risk assessment in the process industries: evaluation and application of current control banding methods. In 14. International Symposium on Loss Prevention and Safety Promotion in the Process Industry (Vol. 31, pp. 949-954). AIDIC. Milano.
27. 27. Silva, F., Sousa, S. P. B., Arezes, P., Swuste, P., Ribeiro, M. C. S., & Baptista, J. S. (2015). Qualitative risk assessment during polymer mortar test specimens preparation-methods comparison. In Journal of Physics: Conference Series (Vol. 617, No. 1, p. 012037). IOP Publishing.
28. 28. Occupational Safety and Health Administration. (2013). OSHA Fact Sheet: Working Safely with Nanomaterials. Occupational Safety and Health Administration. [https://www.osha.gov/Publications/OSHA_FS-3634.pdf]
29. 29. Eastlake, A., Hodson, L., Geraci, C., & Crawford, C. (2012). A critical evaluation of material safety data sheets (MSDSs) for engineered nanomaterials. Journal of Chemical Health and Safety, 19(5), 1-8.