Erkek Alkol Bağımlılığında Nüks ile Biyokimyasal Etmenler Arasındaki İlişki Var Mıdır?

Öz

Objective: In this study we aimed to observe the biochemical variables which probably relates to relapse in six months after discharge from inpatient unit for patients with male alcohol dependence. Material and Methods: Study sample comprise of 89 consecutive male patients who were treated at Samsun Mental Health Hospital Alcohol and Drug Research, Treatment and Training Center in 2010. After completion of the detoxification phase, patients were divided in two groups according to whether they have been relapsed or not in 6 months after discharge and the biochemical parameters which is taken in the beginning of hospitalization and sociodemographic properties of these two groups have been compared. Results: In this study findings of 89 male patients have been examined comperatively. After six months which is determinated as remission duration; there were no statistical difference between 49 relapsed and 40 non relapsed patients in terms of either biochemical parameters and sociodemographic (p>0,05). Conclusion: In this study which is conducted with male patients diagnosed with alcohol dependence; findings endorse that relapse cannot be envisaged. On the other hand, the difference between urea values which forms a statistical tendency is encouraging to draw up future studies with greater sample sizes

Anahtar Kelimeler

• Alcohol dependence; relapse; biochemical parameters

Erkek Alkol Bağımlılığında Nüks ile Biyokimyasal Etmenler Arasındaki İlişki Var Mıdır?

Öz

Amaç: Bu çalışmanın amacı erkek alkol bağımlılığında yataklı tedavi sonrası altı ay içinde alkol kullanımının yinelenmesini (nüks) öngörme ile ilişkili olabilecek biyokimyasal etmenleri değerlendirmektir. Gereç ve Yöntem: Çalışma grubu olarak, 2010 yılında ardışık olarak Samsun Ruh Sağlığı Hastalıkları Hastanesi Alkol Madde Araştırma Tedavi Merkezi servisinde yatarak tedavi edilen 89 alkol bağımlılığı tanılı hasta belirlenmiştir. Yataklı ünitede detoksifikasyon tedavileri tamamlanan hastalar 6 ay içerisinde alkol kullanımlarının yinelenip yinelenmediği temel alınarak iki gruba ayrılmıştır ve hastaların yatışlarındaki başlangıç biyokimyasal etmenlerin düzeyleri ve sosyodemografik özellikleri ile karşılaştırılmıştır. Bulgular: Belirlenen remisyon süresi olan 6 aylık takip sonucunda tekrar alkol alımı olmayan 40 hasta ile nüks gerçekleşen 49 hasta arasında biyokimyasal parametreler ve sosyodemografik değişkenler açısından istatistiksel bir fark saptanmamıştır (p>0,05). Sonuç: Yatarak tedavi gören alkol bağımlılığı tanısı almış erkeklerde yapılan bu çalışmada nüksün mevcut biyokimyasal etmenlerle öngörülemeyeceği yönünde veriler elde edilmiştir. Buna karşın üre değerlerindeki farkın istatistiksel fark eğilimi oluşturması büyük örneklem sayılı yeni çalışmaların yapılması açısından cesaret vericidir

Anahtar Kelimeler

• Alkol bağımlılığı; nüks; biyokimyasal etmenler

Kaynakça

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