Evaluatıon of olfactory bulb volume anf olfactory sulcus depth ın patıents wıth chronic stroke

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ABSTRACT

Objective: The aim of this study was to evaluate the olfactory bulb (OB) volume and olfactory sulcus depth in patients with chronic stroke.

Patients and Methods: This study was designed as a case-control and retrospective study. OB volumes of the patients with chronic stroke (>6 months) were measured using a 1.5 tesla MRI machine (Philips MRI Systems, Achieva Release 3.2 Level 2013-10-21, Philips Medical) with a standard head coil. OB volumes were measured by using fat suppressed T2 coronal images. The data of the stroke patients were compared to the healthy control subjects.

Results: The study included 45 (21 male/24 female) post-stroke patients with the mean age of 47,7±10,7 years and 45 (19 male/26 female) healthy control subjects with the mean age of 44,5±8,7 years. Right (34,8±10,1 vs. 44,0±7,4 mm³) and left (34,9±10,0 vs. 49,1±6,2 mm³) OB volumes were significantly lower in the stroke group than in the control group. There was no significant difference between the groups when the stroke patients were divided into two groups as the left and the right regarding to affected hemisphere.  However mean value of the OB volume in the both left and right stroke groups were significantly lower than the healthy controls. Olfactory sulcus depth was similar between the groups on the right side (7,0±0,0 vs. 7,0±0,7), however it was higher in the stroke group on the left side (7,1±0,9 vs. 6,7±0,6).

Conclusion: Patients with chronic stroke seem to have decreased OB volumes compared to the healthy control. 

Anahtar Kelimeler

• Cerebrovascular accident; olfactory bulb;olfactory sulcus

Kronik dönemde inme geçirmiş hastaların olfaktör bulbus hacimlerinin ve olfaktör sulkus derinliklerinin değerlendirilmesi

Öz

ÖZET

Amaç: Bu çalışmada kronik dönemdeki inme geçirmiş hastaların olfaktör bulbus (OB) hacimleri ve olfaktör sulcus derinliğini değerlendirmek amaçlandı.

Hastalar ve Yöntem: Bu çalışma retrospektif ve olgu kontrol çalışması olarak planlandı. Kronik dönemde (>6 ay) inme geçirmiş hastaların OB hacimleri manyetik rezonans görüntüleme 1.5-tesla MRG sistemi (Philips MRI Systems, Achieva Release 3.2 Level 2013-10-21, Philips Medical) ile standart kafa coili kullanılarak yapıldı. OB hacim ölçümleri yağ baskılı T2 koronal kesitler kullanılarak yapıldı. İnmeli hastaların verileri sağlıklı kontrol grubu ile karşılaştırıldı.

Bulgular: Çalışmaya yaş ortalaması 47,7±10,7 yıl olan 45 (21 erkek,24 kadın) inme geçirmiş hasta ile yaş ortalaması 44,5±8,7 yıl olan 45 (19 erkek-26 kadın) sağlıklı kontrol dahil edildi. İnme grubu ile kontrol grubu karşılaştırıldığında sağ (34,8±10,1 vs. 44,0±7,4 mm³) ve sol OB (34,9±10,0 vs. 49,1±6,2 mm³) hacimlerinin ortalama değerlerinin inme geçirmiş grupta kontrollere göre belirgin olarak azaldığı görüldü. İnme geçiren hastalar etkilenen hemisfere (sağ/sol) göre ikiye ayrılıp kendi aralarında karşılaştırıldıklarında anlamlı fark gözlenmezken, her iki grupta da ortalama OB hacimleri sağlıklı kontrollere göre anlamlı olarak azalmış bulundu. Olfaktör sulkus derinliği ise sağda gruplar arasında değişiklik göstermezken (7,0±0,0 vs. 7,0±0,7) ve solda inmeli grupta daha yüksek bulundu (7,1±0,9 vs. 6,7±0,6).

Sonuç: İnme sonrası kronik dönemdeki hastalarda olfaktör bulbus hacimlerinin azaldığı görüldü. 

Anahtar Kelimeler

• Serebrovasküler olay; olfaktör bulbus; olfaktör sulkus

Kaynakça

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