CERVICAL DISC DEGENERATION, SEVERITY OF PAIN AND VITAMIN D LEVELS IN PATIENTS WITH CHRONIC NECK PAIN: IS THERE ANY RELATIONSHIP?
Öz
OBJECTIVE: Effects of vitamin D on bone metabolism has been long known. We aimed to detect the relationship between vitamin D levels and intervertebral disc degeneration, disc height and severity of pain in patients with chronic neck pain.
MATERIAL AND METHODS: The data of patients who were admitted to neurosurgery polyclinic with chronic neck pain complaints were analyzed retrospectively, whom their vitamin D levels measured, pain severity (VAS) scores ware noted at the time of admission and were radiologically examined with cervical MRI.
RESULTS: Overall, 123 patients were included in the study. There was a significant relationship in terms of VAS scores between the groups divided on the basis of vitamin D levels (p=0.003). There was no statistically significant relationship in terms of age (p=0.180), gender (p=0. 244/p=0.146), and cervical C5-6 disk height (p= 0.299) in the comparison performed within the groups divided on the basis of vitamin D levels.
CONCLUSIONS: In the present study, it was shown that there is a significant relationship between low vitamin D levels and VAS in patients who had cervical disk degeneration and loss of cervical lordosis. We believe that vitamin D deficiency at a metabolic level should be considered in patients who are admitted with chronic neck pain, who do not exhibit neurologic deficits in the examination, and who do not have disc hernia.
Anahtar Kelimeler
Kaynakça
- 1.Bikle DD: Vitamin D and immune function: understanding common pathways. Current osteoporosis reports. 2009 ;7(2):58-63. 2.Zehnder D, Bland R, Williams MC,et al. Extrarenal expression of 25-hydroxyvitamin D3-1α-hydroxylase. The Journal of ClinicalEndocrinology&Metabolism. 2001;86 (2):888-894.
- 3.Tuffaha M, El Bcheraoui C, Daoud F,et al. Deficiencies under plenty of sun: Vitamin D status among adults in the kingdom of Saudi Arabia, 2013. North American journal of medical sciences. 2015;7(10 ):467-75.
- 4.Heidari B, Shirvani JS, Firouzjahi A, et al. Association between nonspecific skeletal pain and vitamin D deficiency. International journal of rheumatic diseases. 2010;13(3):340-346.
- 5.Pfeifer M, Begerow B, Minne H. Vitamin D and muscle function. Osteoporosis International. 2002; 13(3):187-194.
- 6.Plotnikoff GA, Quigley JM. Prevalence of severe hypovitaminosis D in patients with persistent, nonspecific musculoskeletal pain. Mayo clinic proceedings. 2003; 78 (12):1463-70.
- 7.Lane NE, Gore LR, Cummings SR,et al. Serum vitamin D levels and incident changes of radiographic hip osteoarthritis: a longitudinal study. Arthritis & Rheumatism: Official Journal of the American College of Rheumatology. 1999; 42 (5):854-860.
- 8.Royce PM, Steinmann B. Connective tissue and its heritable disorders: molecular, genetic, and medical aspects. John Wiley & Sons. 2003 159-162.
- 9.Bunout D, Barrera G, Leiva L,et al. Effects of vitamin D supplementation and exercise training on physical performance in Chilean vitamin D deficient elderly subjects. Experimental gerontology. 2006 ; 41 (8):746-752.
Ayrıntılar
Birincil Dil
İngilizce
Konular
Klinik Tıp Bilimleri
Bölüm
Araştırma Makalesi
Yayımlanma Tarihi
11 Mayıs 2020
Gönderilme Tarihi
18 Ekim 2019
Kabul Tarihi
11 Mart 2020
Yayımlandığı Sayı
Yıl 2020 Cilt: 21 Sayı: 2
