Evaluation of Sleep Quality and Sleepiness in Alzheimer 's Patients

Abstract

Sleep disorders are common in neurodegenerative diseases such as Alzheimer's type of Dementia (ATD). It has been reported that sleep disorders are especially prominent in moderate- severe stages of the disease. Sleep disorders may reduce quality of life, cognitive functions and may negatively affect the mood of the patients as well as the caregiver burden. The aim of this study was to evaluate the quality of sleep, sleepiness and related factors in 50 outpatients whom were admitted to the outpatient Geriatric Psychiatry Unit and were received a diagnosis of Alzheimer’s Type of Dementia according to the DSM-IV-TR criteria. A sociodemographic form, the Mini Mental State Examination (MMSE), Pittsburg Sleep Quality Index (PSQI), Epworth Sleepiness Scale (ESS), Zarit Caregiver Burden Interview (ZBI), Functional Activities Questionnaire (FAQ) were applied to the participants and\or their caregivers. Most of the patients (62%) had sleep disturbances. The total ESS scores of the sample were significantly correlated with the FAQ scoresand age, but there was no association between EUS or PSQI scores and other scales as well as the duration of dementia. There was no difference between femaleand male patients in terms of the total PSQI and the total ESS scores. The results of the present study emphasized that sleep disturbances were associated with low level of functionality in patients with ATD, but there was no relation between the sleep disturbance and the caregiver burden. In future studies,developing specific assessment instruments for this group of patients and studying sleep disordersin comparison with healthy elderly people in larger samples are recommended.

Keywords

• Sleep Disturbances,Caregiver Burden,Functionality,Alzheimer type Dementia,Geriatric Psychiatry

Alzheimer Hastalarında Uyku Kalitesi ve Uykululuk Halinin Değerlendirilmesi

Öz

Uyku bozuklukları Alzheimer tipi Demans (ATD) gibi nörodejeneratif hastalıklarda sık görülmektedir. Özellikle hastalığın orta-ileri evresinde uyku bozukluklarının arttığı bildirilmektedir. Bu hastalarda uyku bozuklukları bireyin yaşam kalitesini, bilişsel işlevlerini düşürebilir, duygudurumunu ve bakım verenin yükünü olumsuz etkileyebilir. Bu çalışmada Geriatrik Psikiyatri Birimi polikliniğine ayaktan başvuran ve DSM-IV tanı ölçütlerine göre ATD tanısı alan 50 hastada uyku kalitesi ve uykululuk hali ile bunlarla ilişkili faktörlerin değerlendirilmesi amaçlanmıştır. Hastalara ve/veya yakınlarına sosyodemografik veri formu, Standardize Mini-Mental Test (SMMT), Pittsburgh Uyku Kalitesi İndeksi (PUKİ), Epworth Uykululuk Ölçeği (EUÖ), Zarit Bakıcı Yükü Ölçeği (ZBYÖ) ile İşlevsel Faaliyetler Anketi (İFA) uygulanmıştır. Hastaların çoğunun (%62) uyku sorunu yaşadığı görülmüştür. Hastaların sadece EUÖ puanları ile İFA puanları ve yaş arasında anlamlı pozitif korelasyon bulunmuş, ancak diğer ölçek puanları ve demans süresi ile EUÖ ve PUKİ puanları arasında anlamlı korelasyon saptanmamıştır. Kadın ve erkek hastalar arasında PUKİ ve EUÖ toplam puanları açısından anlamlı fark saptanmamıştır. Sonuç olarak, bu çalışma ATD hastalarında uyku bozukluklarının düşük işlevsellikle ilişkili olduğunu, ancak bakım veren yükünü etkilemediğini göstermiştir. İleride yapılacak çalışmalarda daha büyük örneklemlerde sağlıklı yaşlılarla kıyaslanarak çalışılması ve uyku bozuklukları için bu hasta grubuna özgü ölçüm araçlarının geliştirilmesi önerilir.

Anahtar Kelimeler

• Uyku bozuklukları,Bakım veren Yükü,İşlevsellik,Alzheimer tipi Demans

Kaynakça

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