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Yaşli Popülasyonda Hiponatremiye Yaklaşim

Cilt: 19 Sayı: 2 22 Temmuz 2024
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Approach to Hyponatremia in the Elderly Population

Abstract

Hyponatremia is the most common electrolyte disorder in both hospitalized patients and the normal population. The prevalence of hyponatremia is approximately 8% in the population and increases significantly with age. In older patients, more than one factor often plays a role in the development of hyponatremia. The tendency of the elderly to develop hyponatremia is mainly attributed to impaired water excretion capacity associated with aging and frequent exposure to drugs and diseases associated with hyponatremia. In acute symptomatic hyponatremia, hypertonic saline solution is commonly used to acutely increase serum sodium levels and prevent severe neurological symptoms. In chronic hyponatremia, the rate of correction of serum sodium concentration should be limited to 10 mEq/L/24 h and more safely to 6–8 mEq/L/24 h. Since both the evaluation and treatment of hyponatremia are difficult in the older population, very careful evaluation is required.

Keywords

Hyponatremia , geriatrics , drugs

Kaynakça

  1. Ioannou P, Panagiotakis S, Tsagkaraki E, Tsioutis C, Fragkiadakis K, Gikas A, et al. Increased Mortality in Elderly Patients Admitted with Hyponatremia: A Prospective Cohort Study. J Clin Med. 2021;10:10(14):3059.
  2. Liamis G, Rodenburg EM, Hofman A, Zietse R, Stricker BH, Hoorn EJ. Electrolyte disorders in community subjects: prevalence and risk factors. Am J Med. 2013;126(3):256–263.
  3. Upadhyay A, Jaber BL, Madias NE. Incidence and prevalence of hyponatremia. Am J Med .2006;119:0-35.
  4. Woodward M, Gonski P, Grossmann M, Obeid J, Scholes R, Topliss DJ. Diagnosis and management of hyponatremia in the older patient. Intern Med J. 2018; 48(Suppl 1): 5-12.
  5. Miller M. Hyponatremia: age-related risk factors and therapy decisions. Geriatrics. 1998 ;53(7):32-3.
  6. Frenkel WN, van den Born BJ, van Munster BC, Korevaar JC, Levi M, de Rooij SE. The association between serum sodium levels at the time of admission and mortality and morbidity in acutely admitted elderly patients: a prospective cohort study. J Am Geriatr Soc. 2010;58(11):2227–2228.
  7. Zhang X, Li XY. Prevalence of hyponatremia among older inpatients in a general hospital. Eur Geriatr Med. 2020;11(4):685-692.
  8. Zheng Y, Zheng FP, Li H. The prevalence and causes of hyponatremia in hospitalized patients. 2020 1;59(1):29-34.
  9. Hawkins RC. Age and gender as risk factors for hyponatremia and hypernatremia. Clin Chim Acta. 2003;337:169-172.
  10. Siregar P. The risk of hyponatremia in the elderly compared with younger in the hospital inpatient and outpatient. Acta Med Indones. 2011;43:158-161.

Kaynak Göster

AMA
1.Tüzün D. Approach to Hyponatremia in the Elderly Population. KSÜ Tıp Fak Der. 2024;19(2):85-90. doi:10.17517/ksutfd.1206810