NSAID Kullanan Her Hastada Gastrik Profilaksi Gerekli mi?

Kadir Gişi; Murat İspiroğlu; Bülent Kantarçeken

doi:10.17517/ksutfd.671049

NSAID Kullanan Her Hastada Gastrik Profilaksi Gerekli mi?

Öz

Non-steroid anti-inflamatuar ilaçları (NSAID) (Aspirin dahil) kullananlarda risk faktörlerine bağlı olarak; %3- 4.5 klinik gastrointestinal (GİS) sistem olayı, 1/70 semptomatik ülser, 1/5 endoskopik ülser, %1.5 (1-4) (major kanama, perforasyon, obstruksiyon vd.) ciddi komplikasyon, 1/150 kanayan ülser, 1/1200 ölüm gelişeceği tahmin edilmektedir. Non-steroid ani-inflamatuar ilaçlar (NSAID) (Aspirin dahil) gastrik ve düodenal ülserle ilişkili anlamlı derecede morbidite ve mortaliteye neden olurlar. Gastrointestinal olay gelişiminde NSAID’ların kendine ait özelliklerine göre risk 20 kata kadar, seçilen doza görede risk 3-7 kata kadar değişebilmektedir. Helicobacter pylori (H. Pylori) ve NSAID peptik ülser oluşumunda bağımsız iki risk faktörüdür. H.pylori eradikasyonu ülser komplikasyonlarını azaltmaktadır. NSAİD kullanan yüksek riskli hastalarda öncelikle misoprostol ( 600mg/gün ve üstü) veya PPI önerilmelidir.Bu derlemede NSAİ ilaç kullanan ve kullanmak zorunda olan hastalarda GİS proflaksisi gerekliliğinin değerlendirilmesi amaçlandı.

Anahtar Kelimeler

Primer proflaksi,,NSAİİ kullanımı,,Proton pompa inhibitörü

Kaynakça

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Ayrıntılar

Birincil Dil

Türkçe

Konular

Sağlık Kurumları Yönetimi

Bölüm

Derleme

Yazarlar

Kadir Gişi ^*
0000-0003-4082-4832
Türkiye

Murat İspiroğlu
0000-0002-0655-7235
Türkiye

Bülent Kantarçeken
0000-0003-4214-817X
Türkiye

Yayımlanma Tarihi

16 Ekim 2020

Gönderilme Tarihi

9 Ocak 2020

Kabul Tarihi

2 Mart 2020

Yayımlandığı Sayı

Yıl 2020 Cilt: 15 Sayı: 3

DOI

https://doi.org/10.17517/ksutfd.671049

IZ

https://izlik.org/JA78TS47DM

APA

Gişi, K., İspiroğlu, M., & Kantarçeken, B. (2020). NSAID Kullanan Her Hastada Gastrik Profilaksi Gerekli mi? Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi Dergisi, 15(3), 69-75. https://doi.org/10.17517/ksutfd.671049

AMA

1.Gişi K, İspiroğlu M, Kantarçeken B. NSAID Kullanan Her Hastada Gastrik Profilaksi Gerekli mi? KSÜ Tıp Fak Der. 2020;15(3):69-75. doi:10.17517/ksutfd.671049

Chicago

Gişi, Kadir, Murat İspiroğlu, ve Bülent Kantarçeken. 2020. “NSAID Kullanan Her Hastada Gastrik Profilaksi Gerekli mi?”. Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi Dergisi 15 (3): 69-75. https://doi.org/10.17517/ksutfd.671049.

EndNote

Gişi K, İspiroğlu M, Kantarçeken B (01 Ekim 2020) NSAID Kullanan Her Hastada Gastrik Profilaksi Gerekli mi? Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi Dergisi 15 3 69–75.

IEEE

[1]K. Gişi, M. İspiroğlu, ve B. Kantarçeken, “NSAID Kullanan Her Hastada Gastrik Profilaksi Gerekli mi?”, KSÜ Tıp Fak Der, c. 15, sy 3, ss. 69–75, Eki. 2020, doi: 10.17517/ksutfd.671049.

ISNAD

Gişi, Kadir - İspiroğlu, Murat - Kantarçeken, Bülent. “NSAID Kullanan Her Hastada Gastrik Profilaksi Gerekli mi?”. Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi Dergisi 15/3 (01 Ekim 2020): 69-75. https://doi.org/10.17517/ksutfd.671049.

JAMA

1.Gişi K, İspiroğlu M, Kantarçeken B. NSAID Kullanan Her Hastada Gastrik Profilaksi Gerekli mi? KSÜ Tıp Fak Der. 2020;15:69–75.

MLA

Gişi, Kadir, vd. “NSAID Kullanan Her Hastada Gastrik Profilaksi Gerekli mi?”. Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi Dergisi, c. 15, sy 3, Ekim 2020, ss. 69-75, doi:10.17517/ksutfd.671049.

Vancouver

1.Kadir Gişi, Murat İspiroğlu, Bülent Kantarçeken. NSAID Kullanan Her Hastada Gastrik Profilaksi Gerekli mi? KSÜ Tıp Fak Der. 01 Ekim 2020;15(3):69-75. doi:10.17517/ksutfd.671049

NSAID Kullanan Her Hastada Gastrik Profilaksi Gerekli mi?

Öz

Anahtar Kelimeler

Kaynakça

Ayrıntılar

Birincil Dil

Konular

Bölüm

Yazarlar

Yayımlanma Tarihi

Gönderilme Tarihi

Kabul Tarihi

Yayımlandığı Sayı

DOI

IZ

Kaynak Göster