Effects of use of inotropic agents on ABO and RH blood groups in adult cardiac surgery
Abstract
Objective:The objective of this study is to investigate the effects of use of inotropic agents on ABO and RH blood groups in adult cardiac surgery.
Method: We retrospectively analyzed the hospital information management system records and files of patients who underwent CPB between June 15, 2017 and November 15, 2019.We evaluated the patients’ age, sex, blood group, diagnosis, use of fentanyl and demizolam in induction, CPB time, cross-clamp time, operation time, use of intraoperative and postoperative inotropic agents, postoperative intubation period, and day of intensive care hospitalization.
Results:There was no difference between the ABO and RH blood groups in terms of use of fentanyl and demizolam in induction,CPB time, cross-clamp time, postoperative intubation time, day of intensive care hospitalization, and operation time. Postoperative dopamine use was higher in blood groups A, B, and O than its intraoperative use (p=0.001,p=0.014,p=0.001). Postoperative norepinephrine use was higher among A,B,and O blood groups than its intraoperative use (p=0.001,p=0.025,p=0.002). Postoperative nitroglycerin use was higher in blood group O than its intraoperative use (p=0.034).The use of postoperative dopamine, norepinephrine, and nitroglycerin was higher in the RH (+) group as compared to intraoperative use (p = 0.001,p=0.001,p=0.011). Postoperative norepinephrine use was higher in the RH (–) group than in its intraoperative use (0.004). The use of intraoperative nitroglycerin in the RH (+) group was higher as compared to the RH (–) group (p=0.042).
Conclusion:Our study found that the use of inotropic agents was different in ABO and RH blood groups.
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