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Serum 25-Hydroxy Vitamin D Level Does Not Reflect The Severity of Wart: A Cross-Sectional Study

Cilt: 17 Sayı: 2 15 Temmuz 2022
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Serum 25-Hydroxy Vitamin D Level Does Not Reflect The Severity of Wart: A Cross-Sectional Study

Öz

Objective: Verruca vulgaris is a benign epithelial proliferative disease caused by human papilloma viruses. Topical and intralesional vitamin D applications are effective methods in the treatment of warts. However, the relationship between the disease and serum vitamin D levels is unclear. The correlation between the severity of the disease and serum 25-hydroxy vitamin D (25-OH vit D) levels have not been previously investigated. This study aimed to determine the relationship between serum 25-OH vit D levels and disease severity in patients with verruca vulgaris. Material and Methods: Serum 25-OH vit D levels were evaluated in 40 patients with verruca vulgaris and 43 sex and age-matched healthy volunteers. Serum 25-OH vit D levels were compared by grouping the patients according to the severity and duration of verruca vulgaris disease Results: There was no significant difference in serum 25-OH vit D levels between verruca vulgaris patients and the control group (p=0.760). There was no significant difference between serum 25-OH vit D level, disease severity and disease duration in the verruca vulgaris group (p =0.102, p=0.257, respectively). Conclusion: Serum 25-OH vit D level was not associated with verruca vulgaris. Serum 25-OH vit D levels are not related to disease severity and duration. Our data do not support vitamin D supplementation for the prevention or treatment of verruca vulgaris.

Anahtar Kelimeler

Disease severity, Serum 25-hydroxy vitamin D, Verruca vulgaris

Destekleyen Kurum

Yok.

Kaynakça

  1. Egawa K, Ono T. Topical vitamin D3 derivatives for recalcitrant warts in three immunocompromised patients. Br J Dermatol. 2004;150(2):374–376.
  2. Mitsuhashi Y, Kawaguchi M, Hozumi Y, Kondo S. Topical vitamin D3 is effective in treating senile warts possibly by inducing apoptosis. J Dermatol. 2005;32(6):420–423.
  3. Imagawa I, Suzuki H. Successful treatment of refractory warts with topical vitamin D3 derivative (maxacalcitol, 1 alpha, 25-dihydroxy-22-oxacalcitriol) in 17 patients. J Dermatol. 2007;34(4):264–266.
  4. Moscarelli L, Annunziata F, Mjeshtri A, Paudice N, Tsalouchos A, Zanazzi M et al. Successful treatment of refractory wart with a topical activated vitamin d in a renal transplant recipient. Case Rep Transplant. 2011;2011:368623.
  5. Osborne JE, Hutchinson PE. Vitamin D and systemic cancer: is this relevant to malignant melanoma? Br J Dermatol. 2002;147(2):197–213.
  6. Aktaş H, Ergin C, Demir B, Ekiz Ö. Intralesional vitamin D injection may be an effective treatment option for warts. J Cutan Med Surg. 2016;20(2):118–122.
  7. Raghukumar S, Ravikumar BC, Vinay KN, Suresh MR, Aggarwal A, Yashovardhana DP. Intralesional Vitamin D3 Injection in the Treatment of Recalcitrant Warts: A Novel Proposition. J Cutan Med Surg. 2017;21(4):320–324.
  8. Kavya M, Shashikumar BM, Harish MR, Shweta BP. Safety and efficacy of intralesional vitamin D3 in cutaneous warts: an open uncontrolled trial. J Cutan Aesthet Surg. 2017;10(2):90–94.
  9. Jakhar D, Kaur I, Misri R. Intralesional vitamin D3 in periungual warts. J Am Acad Dermatol. 2019;80(5):111–112.
  10. Öztekin C, Öztekin A, Taştan K, Özmen GG, Pektaş SD. The association between verruca vulgaris and vitamin D: is there a casual link? Acta Medica Mediterranea, 2018,34(4):1047–1050.

Kaynak Göster

APA
Ertuğrul, G., & Aktaş, H. (2022). Serum 25-Hydroxy Vitamin D Level Does Not Reflect The Severity of Wart: A Cross-Sectional Study. Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi Dergisi, 17(2), 15-19. https://doi.org/10.17517/ksutfd.987056
AMA
1.Ertuğrul G, Aktaş H. Serum 25-Hydroxy Vitamin D Level Does Not Reflect The Severity of Wart: A Cross-Sectional Study. KSÜ Tıp Fak Der. 2022;17(2):15-19. doi:10.17517/ksutfd.987056
Chicago
Ertuğrul, Gökşen, ve Habibullah Aktaş. 2022. “Serum 25-Hydroxy Vitamin D Level Does Not Reflect The Severity of Wart: A Cross-Sectional Study”. Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi Dergisi 17 (2): 15-19. https://doi.org/10.17517/ksutfd.987056.
EndNote
Ertuğrul G, Aktaş H (01 Temmuz 2022) Serum 25-Hydroxy Vitamin D Level Does Not Reflect The Severity of Wart: A Cross-Sectional Study. Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi Dergisi 17 2 15–19.
IEEE
[1]G. Ertuğrul ve H. Aktaş, “Serum 25-Hydroxy Vitamin D Level Does Not Reflect The Severity of Wart: A Cross-Sectional Study”, KSÜ Tıp Fak Der, c. 17, sy 2, ss. 15–19, Tem. 2022, doi: 10.17517/ksutfd.987056.
ISNAD
Ertuğrul, Gökşen - Aktaş, Habibullah. “Serum 25-Hydroxy Vitamin D Level Does Not Reflect The Severity of Wart: A Cross-Sectional Study”. Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi Dergisi 17/2 (01 Temmuz 2022): 15-19. https://doi.org/10.17517/ksutfd.987056.
JAMA
1.Ertuğrul G, Aktaş H. Serum 25-Hydroxy Vitamin D Level Does Not Reflect The Severity of Wart: A Cross-Sectional Study. KSÜ Tıp Fak Der. 2022;17:15–19.
MLA
Ertuğrul, Gökşen, ve Habibullah Aktaş. “Serum 25-Hydroxy Vitamin D Level Does Not Reflect The Severity of Wart: A Cross-Sectional Study”. Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi Dergisi, c. 17, sy 2, Temmuz 2022, ss. 15-19, doi:10.17517/ksutfd.987056.
Vancouver
1.Gökşen Ertuğrul, Habibullah Aktaş. Serum 25-Hydroxy Vitamin D Level Does Not Reflect The Severity of Wart: A Cross-Sectional Study. KSÜ Tıp Fak Der. 01 Temmuz 2022;17(2):15-9. doi:10.17517/ksutfd.987056