Hiperkalsemi ve Çoklu Patolojik Kemik Fraktürü ile Başvuran Akut Lenfoblastik Lösemi

Yıl 2018, Cilt: 13 Sayı: 1, 24 - 26, 11.03.2018

Ahmet Girgeç Fatih Temiz Sadık Yurttutan Zübeyde Dinçer Osman Nuri Özen Can Acıpayam

https://doi.org/10.17517/ksutfd.382098

Öz

Hiperkalsemi,  bazı lenfoproliferatif hastalıklarda sıkça görülmesine rağmen çocukluk çağı akut lenfoblastik lösemilerinde nadir bir komplikasyondur. Bu yazıda hiperkalsemi ve çoğul patolojik kemik kırıkları ile başvuran ve akut lösemi tanısı konulan 8 yaşında bir erkek olgu sunulmuştur. Hiperkalsemi etkeni olabilecek tüm nedenler araştırıldı ve laboratuar testler normal bulundu. Hiperkalsemi, intravenöz izotonik sodyum klorür, furosemid, steroidler ve bifosfonatlar ile tedavi edildi. Hiperkalsemi, çocukluk çağı akut lenfoblastik löseminin başlangıç laboratuvar bulgusu olabilir. Tekrarlayan laboratuvar ve periferik yayma incelemeleri hiperkalseminin ayırıcı tanısında önemlidir.

Anahtar Kelimeler

akut lenfoblastik lösemi, hiperkalsemi

Hiperkalsemi ve Çoklu Patolojik Kemik Fraktürü ile Başvuran Akut Lenfoblastik Lösemi

Öz

Hypercalcemia is common in some
lymphoproliferative disorders, but is a rare complication of acute
lymphoblastic leukemia in childhood. We report a 8-year-old boy who presented
with hypercalcemia and multiple pathologic bone fracture was diagnosed to have
acute lymphoblastic leukemia. All the disorders that could be the reason of
hypercalcemia and the laboratory tests
were within normal limits. Hypercalcemia was treated with intravenous isotonic
sodium chloride solution, furosemide and biphosphonates. Hypercalcemia may be a
presenting laboratory finding of acute lymphoblastic leukemia in childhood.
Repeat laboratory and peripheral blood smear examinations are important for
differential diagnosis of hypercalcemia.

Anahtar Kelimeler

akut lenfoblastik lösemi, hiperkalsemi

Kaynakça

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