Crimean Congo Hemorrhagic Fever Case With Diarrhea

Yıl 2018, Cilt: 13 Sayı: 3, 85 - 87, 15.11.2018

Ahmet Şahin

https://doi.org/10.17517/ksutfd.405338

Öz

Crimean-Congo hemorrhagic fever (CCHF) is a zoonotic
infectious disease with high mortality among viral haemorrhagic fever
syndromes. The patient was a 37-year-old male who did not know that it was a
tick-related disease and applied with fever, fatigue, fatigue, headache. On
physical examination, the general condition was stable and there was widespread
widespreadness in the patient with consciousness open. In laboratory tests,
pancytopenia and liver function tests were found to be elevated.  Clinical
and laboratory findings of the patient who was considered viral haemorrhagic
fever were positive for PCR test of CCHF polymerase chain reaction Patient in whom supportive care is initiated is improved after
approximately two weeks of follow-up. CCHF, which has been seen as endemic in
our country in recent years, is seen as a shepherd in Çankırı province in this
case.

Anahtar Kelimeler

CCHF, Diarrhea, Fever

Diyare ile Başvuran Kırım Kongo Kanamalı Ateşi Olgusu

Öz

Kırım-Kongo kanamalı ateşi (KKKA), viral
hemorajik ateş sendromları arasında yüksek mortalite ile seyredebilen zoonotik bir enfeksiyon
hastalığıdır. Başvuru sırasında kene teması olduğunu bilmeyen, ancak ateş,
halsizlik, baş ağrısı ve ishal ile başvuran 37 yaşındaki erkek hasta takip ve
tedavi amaçlı yatırıldı. Fizik muayenesinde genel durumu stabil ve bilinci açık
olan hastanın batında yaygın hassasiyeti vardı. Laboratuvar tetkiklerinde pansitopeni
ve karaciğer fonksiyon testlerinde yükseklik saptandı. Klinik ve laboratuvar
bulgularla viral hemorajik ateş düşünülen hastanın KKKA polimeraz zincir
reaksiyonu (PCR) testi pozitif saptandı. Destek tedavisi başlanan hasta
yaklaşık iki haftalık  takip  sonrası iyileşti. Son yıllarda ülkemizde endemik
olarak görülen KKKA, bu olguda Çankırı ilinde çobanlık yapan bir kişide
görülmüştür.

Anahtar Kelimeler

KKKA, Diyare, Ateş

Kaynakça

• 1. Ergonul O. Crimean-Congo haemorrhagic fever. Lancet Infect Dis 2006; 6: 203-14.
• 2. Burt FJ, Leman PA, Smith JF, et al. The use of a reverse transcriptionpolymerase chain reaction for the detection of viral nucleic acid in the diagnosis of Crimean-Congo hemorrhagic fever. J Virol Methods 1998; 70:129–37.
• 3. Kırım-Kongo Kanamalı Ateşi [İnternet]. Ankara: Sağlık Bakanlığı Temel Sağlık Hizmetleri Genel Müdürlüğü [erişim 5 Ekim 2008]. http://www.saglik.gov.tr/ KKKA/Default.aspx?F6E10F8892433CFFAAF6AA849816B2EF4376734BED947CDE.
• 4. Mardani M, Keshtkar-Jahromi M. Crimean-Congo hemorrhagic fever. Arch Iran Med. 2007;10:204-214.
• 5. Whitehouse CA. Crimean-Congo hemorrhagic fever. Antiviral Res. 2004;64:145-160.
• 6. Centers for Disease Control and Prevention. Viral hemorrhagic fever: initial management of suspected and confirmed cases. MMWR Morb Mortal Wkly Rep 1983; 32(Suppl 2):27S–38S.
• 7. Belet N, Top A, Terzi O, Arslan HN, Baysal K, Sensoy G. Evaluation of children with Crimean-Congo hemorrhagic fever in the central Blacksea region. Pediatr Infect Dis J. 2014 Aug;33(8):e194-7.
• 8. Ergonul O: Treatment of Crimean–Congo hemorrhagic fever. Antiviral Res. 78(1), 125–131 (2008).
• 9. Tignor GH, Hanham CA: Ribavirin efficacy in an in vivo model of Crimean–Congo hemorrhagic fever virus (CCHF) infection. Antiviral Res. 22(4), 309–325 (1993).
• 10. Izadi S, Salehi M: Evaluation of the efficacy of ribavirin therapy on survival of Crimean–Congo hemorrhagic fever patients: a case–control study. Jpn. J. Infect. Dis. 62(1), 11–15 (2009).
• 11. Tasdelen Fisgin N, Ergonul O, Doganci L, Tulek N: The role of ribavirin in the therapy of Crimean–Congo hemorrhagic fever: early use is promising. Eur. J. Clin. Microbiol. Infect. Dis.28(8), 929–933 (2009).
• 12. Koksal I, Yilmaz G, Aksoy F et al.: The efficacy of ribavirin in the treatment of Crimean–Congo hemorrhagic fever in Eastern Black Sea region in Turkey. J. Clin. Virol. 47(1), 65–68 (2010).
• 13. Elaldi N, Bodur H, Ascioglu S et al.: Efficacy of oral ribavirin treatment in Crimean–Congo haemorrhagic fever: a quasi-experimental study from Turkey. J. Infect. 58(3), 238–244 (2009).