Araştırma Makalesi
BibTex RIS Kaynak Göster

Evaluation of the Acute and Chronic Effect of Smokeless Tobacco on Anterior Segment Parameters

Yıl 2021, Cilt: 16 Sayı: 2, 208 - 213, 07.07.2021
https://doi.org/10.17517/ksutfd.895430

Öz

Aim: To evaluate the acute and chronic effects of smokeless tobacco (ST) on the anterior segment parameters using optical biometry.
Material and Method: The comparative study included 53 right eyes of 53 subjects (study group), who used ST and 54 right eyes of 54 healthy subjects without ST (control group). Following a full ophthalmological examination, baseline measurements were taken with optical biometry and these measurements were repeated at 5, 30 and 60 mins after using ST. Central corneal thickness (CCT) (µm), anterior chamber depth (ACD) (mm), lens thickness (LT) (mm), pupillary diameter (PD) (mm), and axial length (AL) (mm) were measured.
Result: No statistical difference between the control group and study group in terms of CCT, AL, ACL and LT (p=0.771, p=0.706, p=0.546, p=0.984, respectively) however, PD values were statistically significantly different (p=0.040) in baseline measurements. In the study group, similary, no statistically significant difference was determined between the measurements taken before and after ST use in respect of CCT, AL, ACD, and LT (p=0.660, p=0.058, p=0.344, p=0.059, respectively). The changes in the PD value with the use of ST were determined to be statistically significant (p<0.01). Thus, the difference in PD value was found to be statistically significant between 5 and 30 mins, between 5 and 60 mins, and between 30 and 60 mins after ST use (p<0.01, p<0.01, p<0.01 respectively).
Conclusion: ST use did not show any acute and chronic effect on CCT, AL, ACD and LT. However, there was seen to be a significant effect on PD.

Kaynakça

  • 1) Malovichco MV, Zeller I, Krivokhizhina TV, Xie Z, Lorkiewicz P, Agarwal A, et al. Systemic Toxicity of Smokeless Tobacco Products in Mice. Nicotine Tob Res. 2019 Jan 1;21(1):101-10.
  • 2) İnanç Y, Orhan FÖ, İnanç Y. The effects of Maras powder use on patients with migraine. Neuropsychiatr Dis Treat. 2018 May 7;14:1143-8.
  • 3) Sucakli MH, Ozkan F, Inci MF, Celik M, Keten HS, Bozoğlan O. Effects of smokeless tobacco (Maras powder) use on carotid intima media thickness. Med Sci Monit. 2013 Oct 16;19:859-64.
  • 4) Çömez A, Karaküçük Y, Beyoğlu A. Evaluation of the effect of smokeless tobacco (Maras powder) on choroidal and retinal blood flow: an optical coherence tomography angiography study. Int Ophthalmol. (2020) Jun 40(6):1367-76.
  • 5) Kahraman H, Sucaklı MH, Atilla N, Arpağ H, Bozkuş F, Köksal N. The Effect of Working in Smoke-Free Workplace on use of Smoking and Smokeless Tobacco. Turk Thorac J. 2017 Jan;18(1):14-8.
  • 6) Aral M, Ekerbicer HC, Celik M, Ciragil P, Gul M. Comparison of effects of smoking and smokless tobacco ‘’Maras powder’’ on immune system parameters. Mediators Inflamm. 2006;2006(3):85019.
  • 7) Güven A, Köksal N, Büyükbeşe MA, Cetinkaya A, Sökmen G, Aksu E, et al. Effects of using a different kind of smokeless tobacco on cardiac parameters: ‘’Maras Powder’’. Anadolu Kardiyol Derg.2003 Sep;3(3):230-5.
  • 8) Erdem U, Gundogan FC, Dinc UA, Yolcu U, Ilhan A, Altun S. Acute effect of cigarette smoking on pupil size and ocular aberrations: a pre- and postsomoking study. J Ophthalmol. 2015;2015:625470.
  • 9) Duman R, Duman R, Sabaner MC, Çetinkaya E. Effect of smoking on the thickness of retinal layers in healthy smokers. Cutan Ocul Toxicol. 2017 Dec;36(4):366-9.
  • 10) Dervişoğulları MS, Totan Y, Tenlik A, Yüce A, Güler E. Effect of smoking on retina nerve fiber layer and ganglion cell-inner plexiform layer complex. Cutan Ocul Toxicol. 2015;34(4):282-5.
  • 11) Golabchi K, Abtahi MA, Salehi A, Jahanbani-Ardakani H, Ghaffari S, Farajzadegan Z. The effects of smoking on corneal endothelial cells: a cross-sectional study on a population from Isfahan, Iran. Cutan Ocul Toxicol. 2018 Mar;37(1):9-14.
  • 12) Bardak H, Gunay M, Bardak Y, Ercalik Y, Imamoglu S, Yildiz E, et al. Evaluation of the acte changes in objective accommodation, pupil size and ocular wavefront aberrationns after cigarette smoking. Cutan Ocul Toxicol. 2017 Mar;36[1]:25-8.
  • 13) Sayın N, Kara N, Pekel G, Altınkaynak H. Effects of chronic smoking on central corneal thickness, endotelial cell, and dry eye parameters. Cutan Ocul Toxicol. 2014 Sep;33(3):21-5.
  • 14) Sobacı G, Erdem U, Gündoğan FÇ, Musayev S. The effect of chronic smoking on the pupil and photosress recovery time. Ophthalmic Res. 2013;49(3):167-70.
  • 15) Cankurtaran V, Tekin K. Cumulative Effects of Smoking and Diabetes Mellitus on Corneal Endothelial Cell Parameters. Cornea. 2019 Jan;38(1):78-83.
  • 16) Ilhan N, Ilhan O, Coşkun M, Daglioglu MC, Ayhan Tuzcu E, Kahraman H, et al. Effects os Smoking on Central Corneal Thickness and the Corneal Endothelial Cell Layer in Otherwise Healthy Subjects. Eye Contact Lens. 2016 Sep;42(5):303-7.
  • 17) Kara S, Gencer B, Türkön H, Ersan I, Ozkanoglu Ekim Y, Arikan S, et al. The Effect of Smoking on Corneal Endothelial Cell. Semin Ophthalmol. 2017;32(2):223-7.
  • 18) Raju P, George R, Ve Ramesh S, Arvind H, Baskaran M, Vijaya L. Influence of tobacco use on cataract development. Br J Ophthalmol. 2006 Nov;90(11):1374-7.
  • 19) Orhan FÖ, Özer UG, Çelik M, Biter E, Karaaslan MF. Maras powder usage among Turkish psychiatric outpatients. Subst Use Misuse. 2011;46(4):486-91.
  • 20) Wang D, Huang Y, Huang C, Wu P, Lin J, Zheng Y, et al. Association analysis of cigarette smoking with onset of primary open-angle glaucoma-related biometric parameters. BMC Ophthalmol. 2012 Nov 27;12:59.
  • 21) Tutka P, Mosiewicz J, Wielosz M. Pharmacokinetics and metabolism of nicotine. Pharmacol Rep. 2005 Mar-Apr;57(2):143-53.

Dumansız Tütünün Ön Segment Parametreleri Üzerindeki Akut ve Kronik Etkisinin Değerlendirilmesi

Yıl 2021, Cilt: 16 Sayı: 2, 208 - 213, 07.07.2021
https://doi.org/10.17517/ksutfd.895430

Öz

Amaç: Smokeless Tobacco (ST) kullanımının oküler ön segment üzerine akut etkisinin optik biyometri ile değerlendirilmesi.
Materyal ve Metod: ST kullanan, herhangi bir sistemik ve oküler patolojisi olmayan 32 bireyin 32 sağ gözü çalışmaya dahil edildi. Bireylerin tam bir oftalmolojik muayenesinden sonra optik biyometri ile baseline ölçümü gerçekleştirildi. ST kullanımından sonra 5. Dk, 30. Dk ve 60. Dk da optik biometri ölçümleri tekrar edildi. Bu ölçümlerde, Santral kornea kalınlığı (CCT) (µm), ön kamara derinliği (ACD) (mm), lens kalınlığı (LT) (mm), pupiller diamater (PD) (mm) ve aksiyal uzunluk (AL) (mm) da oluşan akut değişimler incelendi.
Bulgular: ST kullanımı öncesi ve kullanımdan sonraki ortalama CCT, AL, ACD ve LT açısından istatistiksel olarak anlamlı fark saptanmadı (sırası ile p=0.62, p=0.72, p=0.77, p=0.72). PD açısından ST kullanımı ile oluşan değişimler için istatistiksel olarak anlamlı fark saptanmıştır (p<0.01).
Bu farklılık ST kullanımı öncesi ile kullandıktan sonraki 5.dk ile 30.dk arasında anlamlı iken 60.dk da ki ölçüm arasında anlamlı görülmedi (sırası ile p<0.01, p<0.01, p=0.71). ST kullanımı sonrası 5.dk ile 30.dk ve 60.dk arasında anlamlı fark bulundu (sırası ile p<0.01, p<0.01). Benzer olarak 30.dk ile 60.dk arasında istatistiksel olarak anlamlı fark tespit edildi (p<0.01).
Sonuç: ST kullanımının akut olarak oküler ön segmentte CCT, AL, ACD ve LT üzerine etkisi görülememiştir. Fakat PD üzerine belirgin etki göstermiştir. Bu etki nikotinin sempatik ve parasempatik sistemi etkilemiş olmasından dolayı kaynaklanmış olabilir. ST nin toplumda ön görüldüğü gibi en azından göz üzerine daha zararlı olmadığını ve PD deki değişimin günlük yaşamda zorluklar oluşturabileceğini düşünüyoruz.

Kaynakça

  • 1) Malovichco MV, Zeller I, Krivokhizhina TV, Xie Z, Lorkiewicz P, Agarwal A, et al. Systemic Toxicity of Smokeless Tobacco Products in Mice. Nicotine Tob Res. 2019 Jan 1;21(1):101-10.
  • 2) İnanç Y, Orhan FÖ, İnanç Y. The effects of Maras powder use on patients with migraine. Neuropsychiatr Dis Treat. 2018 May 7;14:1143-8.
  • 3) Sucakli MH, Ozkan F, Inci MF, Celik M, Keten HS, Bozoğlan O. Effects of smokeless tobacco (Maras powder) use on carotid intima media thickness. Med Sci Monit. 2013 Oct 16;19:859-64.
  • 4) Çömez A, Karaküçük Y, Beyoğlu A. Evaluation of the effect of smokeless tobacco (Maras powder) on choroidal and retinal blood flow: an optical coherence tomography angiography study. Int Ophthalmol. (2020) Jun 40(6):1367-76.
  • 5) Kahraman H, Sucaklı MH, Atilla N, Arpağ H, Bozkuş F, Köksal N. The Effect of Working in Smoke-Free Workplace on use of Smoking and Smokeless Tobacco. Turk Thorac J. 2017 Jan;18(1):14-8.
  • 6) Aral M, Ekerbicer HC, Celik M, Ciragil P, Gul M. Comparison of effects of smoking and smokless tobacco ‘’Maras powder’’ on immune system parameters. Mediators Inflamm. 2006;2006(3):85019.
  • 7) Güven A, Köksal N, Büyükbeşe MA, Cetinkaya A, Sökmen G, Aksu E, et al. Effects of using a different kind of smokeless tobacco on cardiac parameters: ‘’Maras Powder’’. Anadolu Kardiyol Derg.2003 Sep;3(3):230-5.
  • 8) Erdem U, Gundogan FC, Dinc UA, Yolcu U, Ilhan A, Altun S. Acute effect of cigarette smoking on pupil size and ocular aberrations: a pre- and postsomoking study. J Ophthalmol. 2015;2015:625470.
  • 9) Duman R, Duman R, Sabaner MC, Çetinkaya E. Effect of smoking on the thickness of retinal layers in healthy smokers. Cutan Ocul Toxicol. 2017 Dec;36(4):366-9.
  • 10) Dervişoğulları MS, Totan Y, Tenlik A, Yüce A, Güler E. Effect of smoking on retina nerve fiber layer and ganglion cell-inner plexiform layer complex. Cutan Ocul Toxicol. 2015;34(4):282-5.
  • 11) Golabchi K, Abtahi MA, Salehi A, Jahanbani-Ardakani H, Ghaffari S, Farajzadegan Z. The effects of smoking on corneal endothelial cells: a cross-sectional study on a population from Isfahan, Iran. Cutan Ocul Toxicol. 2018 Mar;37(1):9-14.
  • 12) Bardak H, Gunay M, Bardak Y, Ercalik Y, Imamoglu S, Yildiz E, et al. Evaluation of the acte changes in objective accommodation, pupil size and ocular wavefront aberrationns after cigarette smoking. Cutan Ocul Toxicol. 2017 Mar;36[1]:25-8.
  • 13) Sayın N, Kara N, Pekel G, Altınkaynak H. Effects of chronic smoking on central corneal thickness, endotelial cell, and dry eye parameters. Cutan Ocul Toxicol. 2014 Sep;33(3):21-5.
  • 14) Sobacı G, Erdem U, Gündoğan FÇ, Musayev S. The effect of chronic smoking on the pupil and photosress recovery time. Ophthalmic Res. 2013;49(3):167-70.
  • 15) Cankurtaran V, Tekin K. Cumulative Effects of Smoking and Diabetes Mellitus on Corneal Endothelial Cell Parameters. Cornea. 2019 Jan;38(1):78-83.
  • 16) Ilhan N, Ilhan O, Coşkun M, Daglioglu MC, Ayhan Tuzcu E, Kahraman H, et al. Effects os Smoking on Central Corneal Thickness and the Corneal Endothelial Cell Layer in Otherwise Healthy Subjects. Eye Contact Lens. 2016 Sep;42(5):303-7.
  • 17) Kara S, Gencer B, Türkön H, Ersan I, Ozkanoglu Ekim Y, Arikan S, et al. The Effect of Smoking on Corneal Endothelial Cell. Semin Ophthalmol. 2017;32(2):223-7.
  • 18) Raju P, George R, Ve Ramesh S, Arvind H, Baskaran M, Vijaya L. Influence of tobacco use on cataract development. Br J Ophthalmol. 2006 Nov;90(11):1374-7.
  • 19) Orhan FÖ, Özer UG, Çelik M, Biter E, Karaaslan MF. Maras powder usage among Turkish psychiatric outpatients. Subst Use Misuse. 2011;46(4):486-91.
  • 20) Wang D, Huang Y, Huang C, Wu P, Lin J, Zheng Y, et al. Association analysis of cigarette smoking with onset of primary open-angle glaucoma-related biometric parameters. BMC Ophthalmol. 2012 Nov 27;12:59.
  • 21) Tutka P, Mosiewicz J, Wielosz M. Pharmacokinetics and metabolism of nicotine. Pharmacol Rep. 2005 Mar-Apr;57(2):143-53.
Toplam 21 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Kurumları Yönetimi
Bölüm Araştırma Makaleleri
Yazarlar

Abdullah Beyoğlu 0000-0003-1948-7755

Yalçın Karaküçük 0000-0001-6430-2233

Ayşegül Çömez 0000-0002-2628-9426

Ali Meşen 0000-0002-0361-9066

Yayımlanma Tarihi 7 Temmuz 2021
Gönderilme Tarihi 12 Mart 2021
Kabul Tarihi 31 Mart 2021
Yayımlandığı Sayı Yıl 2021 Cilt: 16 Sayı: 2

Kaynak Göster

AMA Beyoğlu A, Karaküçük Y, Çömez A, Meşen A. Evaluation of the Acute and Chronic Effect of Smokeless Tobacco on Anterior Segment Parameters. KSÜ Tıp Fak Der. Temmuz 2021;16(2):208-213. doi:10.17517/ksutfd.895430