EVALUATİON OF THE RELATİONSHİP BETWEEN DİSORDER PARAMETERS AND SLEEPİNG QUALİTY İN ANKYLOSİNG SPONDYLİTİS PATİENTS

Yıl 2021, Cilt: 16 Sayı: 3, 311 - 315, 01.11.2021

Sezgin Zontul Zühal Altay

https://doi.org/10.17517/ksutfd.803282

Cited By: 1

Öz

Objective: The aim of this study was to evaluate the relationship of quality of sleep with disease parameters and other possible reasons of sleep disorder in patients with ankylosing spondylitis. Materials and Methods: 122 patients with ankylosing spondylitis in an ongoing follow-up were included in the study. Patients were divided into two groups according to the Pittsburg Sleep Quality Index due to sleep quality, including patients with good sleep quality and bad sleep quality. Patients were questioned about age, sex, height, weight, marital status, educational status, date of diagnosis, diagnosis center, medical treatments they receive to date, treatment-related side effects, surgery and other known chronic diseases. In addition, CBC, ALT, AST, BUN, creatinine, sedimentation, CRP values of these patients were recorded in the case report form. Patients were evaluated by VAS, short form-36 (SF-36), International RLS Study Group criteria survey, Beck depression, Beck anxiety, BASMI, BASFI and BASDAI scales. Groups were compared with the results obtained from the scale. Results: There were higher rates of poor sleep quality and restless legs syndrome in patients compared to the general population. There were statistically significant differences in pain, quality of life, depression, anxiety, BASFI and BASDAI scores between the groups. There were no statistically significant difference between the groups in terms of BASMI and of restless legs syndrome. Conclusion: It was detected that sleep disorders are common in patients with AS and these disorders were found to be closely associated with pain, disease activity, anxiety, depression, poor quality of life and functional status based on these findings. Also it was concluded that restless legs syndrome is a common situation in patients with AS.

Anahtar Kelimeler

Ankylosing spondylitis, sleep quality, quality of life, restless legs

Ankilozan Spondilit Tanılı Hastalarda Uyku Kalitesinin Hastalık Parametreleri ile Olan İlişkisinin Değerlendirilmesi

Öz

Amaç: Bu çalışmanın amacı, ankilozan spondilit tanılı hastalarda uyku kalitesinin hastalık parametreleri ve uyku bozukluğu yapabilecek diğer bazı nedenler ile olan ilişkisini değerlendirmektir. Gereç ve yöntem: Çalışmaya takipleri devam eden 122 ankilozan spondilit hastası dahil edildi. Hastalar pittsburg uyku kalitesi indeksine göre uyku kalitesi iyi olanlar ve kötü olanlar olmak üzere 2 gruba ayrıldı. Hastalar yaş, cinsiyet, boy, kilo, medeni hal, eğitim durumu, tanı tarihi, tanı konulan merkez, bugüne kadar aldıkları medikal tedaviler, tedaviye bağlı yan etkiler, geçirdiği cerrahi operasyonlar ve başka bilinen kronik hastalık açısından sorgulandı. Ayrıca bu hastalardan alınan rutin kan tetkiklerinden CBC, AST, ALT, BUN, Kreatinin, sedimentasyon, CRP olgu rapor formuna kaydedildi. Hastalar VAS, short form-36 (SF-36), Uluslararası Huzursuz Bacak Sendromu Çalışma Grubu kriterleri anketi, beck depresyon, beck anksiyete, BASMI, BASFI, BASDAI ölçekleri ile değerlendirildi. Gruplar bu ölçeklerden elde edilen sonuçlar ile karşılaştırıldı. Bulgular: Hastalarda genel popülasyona göre daha yüksek oranda kötü uyku kalitesi ve huzursuz bacak sendromu saptandı. Gruplar arasında ağrı, yaşam kalitesi, depresyon, anksiyete, BASFİ ve BASDAİ açısından istatistiksel olarak anlamlı fark saptandı. BASMI ve huzursuz bacak sendromu açısından ise anlamlı fark saptanmadı. Sonuç: Bu bulgulardan yola çıkarak AS hastalarında uyku bozukluklarına sık rastlandığı ve bunun ağrı, hastalık aktivitesi, anksiyete, depresyon, kötü yaşam kalitesi ve fonksiyonel durum ile yakından ilişkili olduğu saptanmıştır. Ayrıca huzursuz bacak sendromunun AS hastalarında sık rastlanan bir durum olduğu sonucuna varılmıştır.

Anahtar Kelimeler

Ankilozan spondilit, uyku kalitesi, yaşam kalitesi, huzursuz bacak

Kaynakça

• Kaynaklar 1. Braun J, Sieper J. Ankylosing spondylitis. Lancet. 2007 Apr 21;369(9570):1379-1390.
• 2. Ward MM. Health-related quality of life in ankylosing spondylitis: a survey of 175 patients. Arthritis Care Res. 1999 Aug;12(4):247-255.
• 3. Jamieson AH, Alford CA, Bird HA, Hindmarch I, Wright V. The effect of sleep and nocturnal movement on stiffness, pain, and psychomotor performance in ankylosing spondylitis. Clin Exp Rheumatol. 1995 Jan-Feb;13(1):73-78.
• 4. Rudwaleit M, Metter A, Listing J, Sieper J, Braun J. Inflammatory back pain in ankylosing spondylitis: a reassessment of the clinical history for application as classification and diagnostic criteria. Arthritis Rheum. 2006 Feb;54(2):569-578.
• 5. Eddy M, Walbroehl GS. Insomnia. Am Fam Physician. 1999 Apr 1;59(7):1911-1916.
• 6. Rajput V, Bromley S. Chronic insomnia: a practical review. Am Fam Physician. 1999 Oct 1;60(5):1431-1438.
• 7. National Heart, Lung, and Blood Institute Working Group on Insomnia. Insomnia: assessment and management in primary care. Am Fam Physician. 1999 Jun;59(11):3029-3038.
• 8. Batmaz İ, Sarıyıldız MA, Dilek B, Bez Y, Karakoç M, Çevik R. Sleep quality and associated factors in ankylosing spondylitis: relationship with disease parameters, psychological status and quality of life. Rheumatol Int. 2013 Apr;33(4):1039-1045.
• 9. Hultgren S, Broman JE, Gudbjornsson B, Hetta J, Lindqvist U. Sleep disturbances in outpatients with ankylosing spondylitis: a questionnaire study with gender implications. Scand J Rheumatol. 2000;29(6):365-369.
• 10. Allen RP, Walters AS, Montplaisir J, Hening W, Myers A, Bell TJ, at al. Restless legs syndrome prevalence and impact: REST general population study. Arch Intern Med. 2005 Jun 13;165(11):1286-1292.
• 11. Bjorvatn B, Leissner L, Ulfberg J, Gyring J, Karlsborg M, Regeur L, at al. Prevalence, severity and risk factors of restless legs syndrome in the general adult population in two Scandinavian countries. Sleep Med. 2005 Jul;6(4):307-312.
• 12. Tekatas A. Pamuk ON. Increased frequency of restless leg syndrome in patients with ankylosing spondylitis. International Journal of Rheumatic Diseases. 2015 Jan;18(1):58-62.
• 13. Sayar K, Arikan M, Yontem T. Sleep quality in chronic pain patients. Can J Psychiatry. 2002 Nov;47(9):844-848.
• 14. Li Y, Zhang S, Zhu J, Du X, Huang F. Sleep disturbances are associated with increased pain, disease activity, depression, and anxiety in ankylosing spondylitis: a case-control study. Arthritis Res Ther. 2012 Oct 11;14(5):215.
• 15. Da Costa D, Zummer M, Fitzcharles MA. Determinants of sleep problems in patients with spondyloarthropathy. Musculoskelet Care. 2009 Sep;7(3):143-161.
• 16. Aydin E, Bayraktar K, Turan Y, Omurlu I, Taştaban E, Sendur OF. Sleep quality in patients with ankylosing spondylitis. Rev Bras Reumatol. 2015 Jul-Aug;55(4):340-345.