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Gastrik Polipler: 10 Yıllık Endoskopik İşlemlerin Retrospektif Analizi

Yıl 2022, Cilt: 17 Sayı: 2, 29 - 34, 15.07.2022
https://doi.org/10.17517/ksutfd.1115823

Öz

Amaç: Mide polipleri genellikle asemptomatik olan ve üst gastroistestinal sistem endoskopisi sırasında tesadüfen saptanan gastrik mukozal çıkıntılardır. Bu çalışmada gastrik poliplerin görülme sıklığı, yerleşim yerleri ve genel özellikleri değerlendirildi.
Gereç ve yöntemler: Üçüncü basamak bir hastanede on yıllık bir süre boyunca gerçekleştirilen üst gastrointestinal sistem endoskopileri retrospektif olarak değerlendirildi. Hastaların demografik özellikleri, gastroskopi endikasyonları, poliplerin morfolojik ve histolojik özellikleri kayıt edildi.
Bulgular: Toplam 25230 gastroskopi hastasının 347'sinde (%1.4) mide polipleri bulundu. Hastaların yaş ortalaması 61.04 ± 15.05 ve %64.3'ü kadındı. Hastaların 124’ü (%35.7) erkek ve 223’ü (%64.3) kadın hastaydı. Polip tespit edilen hastaların en sık endoskopi endikasyonu (%74.1) dispepsiydi. Poliplerin çoğu (%55.3) 5mm’den küçüktü ve en sık yerleşim yeri antrumdu. En sık hiperplastik polip (%44.4) saptandı. Polip saptanan hastaların %42.9’unda Helikobakter pilori pozitifti. Ayrıca adenomatöz poliplerin %58’ine displazi eşlik ediyordu.
Sonuç: Hiperplastik polipler popülasyonumuzdaki en sık görülen polip tipiydi. 5 mm’nin üzerindeki poliplerin (özellikle adenomatöz polipler) displazi odakları içerebileceğinden biyopsi almak yerine tam eksizyonu önerilir. Ayrıca 5 mm’den küçük poliplerin eksize edilmeden endoskopik takibe alınmasının maliyet açısından daha etkin olduğu düşünüldü.

Kaynakça

  • Castro R, Pimentel-Nunes P, Dinis-Ribeiro M. Evaluation and management of gastric epithelial polyps. Best Pract Res Clin Gastroenterol. 2017;31(4):381-387.
  • Amarapurkar AD, Kale KM, Naik LP, Shukla AP. Histomorphological analysis of gastric polyps. Indian J Pathol Microbiol. 2021;64(Supplement):69-72.
  • Cheesman AR, Greenwald DA, Shah SC. Current management of benign epithelial gastric polyps. Curr Treat Options Gastroenterol. 2017;15(4):676-690.
  • Carmack SW, Genta RM, Graham DY, Lauwers G Y. Management of gastric polyps: A pathology-based guide for gastroenterologists. Nat. Rev. Gastroenterol. Hepatol.2009;6:331–341.
  • Cao H, Wang B, Zhang Z, Zhang H, Qu R. Distribution trends of gastric polyps: An endoscopy database analysis of 24121 northern Chinese patients. J Gastroenterol Hepatol. 2012;27(7):1175- 1180.
  • Velázquez-Dohorn ME, López-Durand CF, Gamboa-Domínguez A. Changing Trends in Gastric Polyps. Rev Invest Clin. 2018;70(1):40-45.
  • Yacoub H, Bibani N, Sabbah M, Bellil N, Ouakaa A, Trad D et al. Gastric polyps: a 10-year analysis of 18,496 upper endoscopies. BMC Gastroenterol. 2022;22(1):70.
  • Argüello Viúdez L, Córdova H, Uchima H, Sánchez-Montes C, Ginès À, Araujo I et al. Gastric polyps: Retrospective analysis of 41,253 upper endoscopies. Pólipos gástricos: análisis retrospectivo de 41.253 endoscopias digestivas altas. Gastroenterol Hepatol. 2017;40(8):507-514.
  • Vatansever S, Akpınar Z, Alper E, İpek S, Yazıcıoğlu N, Ekinci N et al. Gastric polyps and polypoid lesions: Retrospective analysis of 36650 endoscopic procedures in 29940 patients. Turk J Gastroenterol. 2015;26(2):117-122.
  • Wang FW, Young SC, Chen RY, Lin KH, Chen YH, Hsu PI et al. The prevalence and risk factors of gastric polyp in asymptomatic patients receiving health examination. Gastroenterol Res Pract 2018;2018:9451905.
  • Morais DJ, Yamanaka A, Zeitune JM, Andreollo NA. Gastric polyps: A retrospective analysis of 26.000 digestive endoscopies. Arq Gastroenterol. 2007;44(1):14-17.
  • Atalay R, Solakoğlu T, Ozer Sarı S, Köseoğlu H, Akın FE, Demirezer Bolat A et al. Evaluation of gastric polyps detected by endoscopy: A single-center study of a four-year experience in Turkey. Turk J Gastroenterol. 2014;25(4):370-373.
  • Çiyiltepe H, Çetin DA, Gündeş E, Aday U, Senger AS, Gülmez S et al. Endoscopic and histopathological features of the upper gastrointestinal system polyps: evaluation of 12.563 procedures. Turk J Surg. 2019;35(2):98-104.
  • Islam RS, Patel NC, Lam-Himlin D, Nguyen CC. Gastric polyps: A review of clinical, endoscopic, and histopathologic features and management decisions. Gastroenterol Hepatol (N Y). 2013;9(10):640-651.
  • Attard TM, Yardley JH, Cuffari C. Gastric polyps in pediatrics: An 18-year hospital-based analysis. Am J Gastroenterol 2002;97:298-301.
  • Markowski AR, Markowska A, Guzinska-Ustymowicz K. Pathophysiological and clinical aspects of gastric hyperplastic polyps. World J Gastroenterol. 2016;22(40):8883-8891.
  • Jain R, Chetty R. Gastric hyperplastic polyps: A review. Dig Dis Sci 2009;54:1839-1846.
  • Orlowska J, Jarosz D, Pachlewski J, Butruk E. Malignant transformation of benign epithelial gastric polyps. Am J Gastroenterol. 1995;90(12):2152-2159.
  • Choudhry U, Boyce HW Jr, Coppola D. Proton pump inhibitor- associated gastric polyps: A retrospective analysis of their frequency, and endoscopic, histologic, and ultrastructural characteristics. Am J Clin Pathol 1998;110:615-621.
  • Kim GH. Proton Pump Inhibitor-Related Gastric Mucosal Changes. Gut Liver. 2021 Sep 15;15(5):646-652.
  • Borch K, Skarsgard J, Franzen L, Mardh S, Rehfeld JF. Benign gastric polyps: morphological and functional origin. Dig Dis Sci 2003;48:1292-1297.
  • Park do Y, Lauwers GY. Gastric polyps: Classification and management. Arch Pathol Lab Med 2008; 132: 633-640.
  • Gencosmanoglu R, Sen-Oran E, Kurtkaya-Yapicier O, Avsar E, Sav A, Tozun N. Gastric polypoid lesions: analysis of 150 endoscopic polypectomy specimens from 91 patients. World Jf Gastroenterol 2003;9:2236-2239.
  • Kamiya T, Morishita T, Asakura H, Miura S, Munakata Y, Tsuchiya M. Long-term follow-up study on gastric adenoma and its relation to gastric protruded carcinoma. Cancer 1982;50:2496- 2503
  • Basuroy R, Srirajaskanthan R, Prachalias A, Quaglia A, Ramage JK. Review article: The investigation and management of gastric neuroendocrine tumours. Aliment Pharmacol Ther. 2014;39(10):1071-1084.
  • Modlin IM, Latich I, Zikusoka M, Kidd M, Eick G, Chan AK. Gastrointestinal carcinoids: The evolution of diagnostic strategies. J Clin Gastroenterol 2006;40(7):572e82.
  • Köseoğlu H, Duzenli T, Sezikli M. Gastric neuroendocrine neoplasms: A review. World J Clin Cases. 2021;9(27):7973-7985.

Gastric Polyps: Retrospective Analysis of a 10-Years Endoscopic Procedure

Yıl 2022, Cilt: 17 Sayı: 2, 29 - 34, 15.07.2022
https://doi.org/10.17517/ksutfd.1115823

Öz

Objective: Gastric polyps are gastric mucosal protrusions that are usually asymptomatic and detected incidentally during upper gastrointestinal system endoscopy. In this study, the incidence, location and general characteristics of gastric polyps were evaluated.
Material and Methods: Upper gastrointestinal system endoscopies performed in a tertiary hospital for a period of ten years were evaluated retrospectively. Demographic characteristics of the patients, gastroscopy indications, morphological and histological characteristics of polyps were recorded.
Results: Gastric polyps were found in 347 (1.4%) of a total of 25230 gastroscopy patients. The mean age of the patients was 61.04±15.05. One hundred and twenty four (35.7%) of the patients were male and 223 (64.3%) were female. The most common endoscopic indication (74.1%) of the patients with polyps
was dyspepsia. Most of the polyps (55.3%) were smaller than 5 mm and the most common site was the antrum. Hyperplastic polyp (44.4%) was detected the most. 42.9% of the patients with polyps were positive for Helicobacter Pylori. In addition, 58% of adenomatous polyps were accompanied by dysplasia.
Conclusion: Hyperplastic polyps were the most common polyp type in our population. Full excision of polyps over 5 mm (especially adenomatous polyps) is recommended instead of biopsy, as they may contain dysplasia foci. In addition, it was thought that taking polyps smaller than 5 mm into endoscopic follow-up without excision was more cost-effective.

Kaynakça

  • Castro R, Pimentel-Nunes P, Dinis-Ribeiro M. Evaluation and management of gastric epithelial polyps. Best Pract Res Clin Gastroenterol. 2017;31(4):381-387.
  • Amarapurkar AD, Kale KM, Naik LP, Shukla AP. Histomorphological analysis of gastric polyps. Indian J Pathol Microbiol. 2021;64(Supplement):69-72.
  • Cheesman AR, Greenwald DA, Shah SC. Current management of benign epithelial gastric polyps. Curr Treat Options Gastroenterol. 2017;15(4):676-690.
  • Carmack SW, Genta RM, Graham DY, Lauwers G Y. Management of gastric polyps: A pathology-based guide for gastroenterologists. Nat. Rev. Gastroenterol. Hepatol.2009;6:331–341.
  • Cao H, Wang B, Zhang Z, Zhang H, Qu R. Distribution trends of gastric polyps: An endoscopy database analysis of 24121 northern Chinese patients. J Gastroenterol Hepatol. 2012;27(7):1175- 1180.
  • Velázquez-Dohorn ME, López-Durand CF, Gamboa-Domínguez A. Changing Trends in Gastric Polyps. Rev Invest Clin. 2018;70(1):40-45.
  • Yacoub H, Bibani N, Sabbah M, Bellil N, Ouakaa A, Trad D et al. Gastric polyps: a 10-year analysis of 18,496 upper endoscopies. BMC Gastroenterol. 2022;22(1):70.
  • Argüello Viúdez L, Córdova H, Uchima H, Sánchez-Montes C, Ginès À, Araujo I et al. Gastric polyps: Retrospective analysis of 41,253 upper endoscopies. Pólipos gástricos: análisis retrospectivo de 41.253 endoscopias digestivas altas. Gastroenterol Hepatol. 2017;40(8):507-514.
  • Vatansever S, Akpınar Z, Alper E, İpek S, Yazıcıoğlu N, Ekinci N et al. Gastric polyps and polypoid lesions: Retrospective analysis of 36650 endoscopic procedures in 29940 patients. Turk J Gastroenterol. 2015;26(2):117-122.
  • Wang FW, Young SC, Chen RY, Lin KH, Chen YH, Hsu PI et al. The prevalence and risk factors of gastric polyp in asymptomatic patients receiving health examination. Gastroenterol Res Pract 2018;2018:9451905.
  • Morais DJ, Yamanaka A, Zeitune JM, Andreollo NA. Gastric polyps: A retrospective analysis of 26.000 digestive endoscopies. Arq Gastroenterol. 2007;44(1):14-17.
  • Atalay R, Solakoğlu T, Ozer Sarı S, Köseoğlu H, Akın FE, Demirezer Bolat A et al. Evaluation of gastric polyps detected by endoscopy: A single-center study of a four-year experience in Turkey. Turk J Gastroenterol. 2014;25(4):370-373.
  • Çiyiltepe H, Çetin DA, Gündeş E, Aday U, Senger AS, Gülmez S et al. Endoscopic and histopathological features of the upper gastrointestinal system polyps: evaluation of 12.563 procedures. Turk J Surg. 2019;35(2):98-104.
  • Islam RS, Patel NC, Lam-Himlin D, Nguyen CC. Gastric polyps: A review of clinical, endoscopic, and histopathologic features and management decisions. Gastroenterol Hepatol (N Y). 2013;9(10):640-651.
  • Attard TM, Yardley JH, Cuffari C. Gastric polyps in pediatrics: An 18-year hospital-based analysis. Am J Gastroenterol 2002;97:298-301.
  • Markowski AR, Markowska A, Guzinska-Ustymowicz K. Pathophysiological and clinical aspects of gastric hyperplastic polyps. World J Gastroenterol. 2016;22(40):8883-8891.
  • Jain R, Chetty R. Gastric hyperplastic polyps: A review. Dig Dis Sci 2009;54:1839-1846.
  • Orlowska J, Jarosz D, Pachlewski J, Butruk E. Malignant transformation of benign epithelial gastric polyps. Am J Gastroenterol. 1995;90(12):2152-2159.
  • Choudhry U, Boyce HW Jr, Coppola D. Proton pump inhibitor- associated gastric polyps: A retrospective analysis of their frequency, and endoscopic, histologic, and ultrastructural characteristics. Am J Clin Pathol 1998;110:615-621.
  • Kim GH. Proton Pump Inhibitor-Related Gastric Mucosal Changes. Gut Liver. 2021 Sep 15;15(5):646-652.
  • Borch K, Skarsgard J, Franzen L, Mardh S, Rehfeld JF. Benign gastric polyps: morphological and functional origin. Dig Dis Sci 2003;48:1292-1297.
  • Park do Y, Lauwers GY. Gastric polyps: Classification and management. Arch Pathol Lab Med 2008; 132: 633-640.
  • Gencosmanoglu R, Sen-Oran E, Kurtkaya-Yapicier O, Avsar E, Sav A, Tozun N. Gastric polypoid lesions: analysis of 150 endoscopic polypectomy specimens from 91 patients. World Jf Gastroenterol 2003;9:2236-2239.
  • Kamiya T, Morishita T, Asakura H, Miura S, Munakata Y, Tsuchiya M. Long-term follow-up study on gastric adenoma and its relation to gastric protruded carcinoma. Cancer 1982;50:2496- 2503
  • Basuroy R, Srirajaskanthan R, Prachalias A, Quaglia A, Ramage JK. Review article: The investigation and management of gastric neuroendocrine tumours. Aliment Pharmacol Ther. 2014;39(10):1071-1084.
  • Modlin IM, Latich I, Zikusoka M, Kidd M, Eick G, Chan AK. Gastrointestinal carcinoids: The evolution of diagnostic strategies. J Clin Gastroenterol 2006;40(7):572e82.
  • Köseoğlu H, Duzenli T, Sezikli M. Gastric neuroendocrine neoplasms: A review. World J Clin Cases. 2021;9(27):7973-7985.
Toplam 27 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Kurumları Yönetimi
Bölüm Araştırma Makaleleri
Yazarlar

Kadir Gişi 0000-0003-4082-4832

Erken Görünüm Tarihi 11 Temmuz 2022
Yayımlanma Tarihi 15 Temmuz 2022
Gönderilme Tarihi 12 Mayıs 2022
Kabul Tarihi 31 Mayıs 2022
Yayımlandığı Sayı Yıl 2022 Cilt: 17 Sayı: 2

Kaynak Göster

AMA Gişi K. Gastric Polyps: Retrospective Analysis of a 10-Years Endoscopic Procedure. KSÜ Tıp Fak Der. Temmuz 2022;17(2):29-34. doi:10.17517/ksutfd.1115823