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Pozitron Emisyon Tomografi – Bilgisayar Tomografi (Pet - Bt) Uygulamalarında Hastanın Aldığı Radyasyon Dozunun Belirlenmesi

Yıl 2020, Cilt: 13 Sayı: 1, 58 - 63, 27.07.2020

Turan Şahmaran , Mehmet Bayburt

Öz

Bu çalışma iki kısımda incelenebilir. İlk kısımda, Termolüminesans Dozimetrelerin (TLD) kalibrasyon işlemi gerçekleştirildi. Böylece Termolüminesans Dozimetre içerisindeki mevcut enerji tuzaklarının tamamen boşaltılması sağlandı. İkinci kısımda, hazır hale gelen Termolüminesans Dozimetreler çekim esnasında hastaların baş, boyun, kalp ve mesane bölgelerine yerleştirilerek dozimetrelerin ışınlanması sağlandı. Işınlanan dozimetreler Ege Üniversitesi Nükleer Bilimler Enstitüsü’nde bulunan lüminesans laboratuvarında okundu. Elde edilen sonuçlar uluslararası komisyon ve komiteler olan ICRP, Nureg/CR ve MIRD raporlarındaki değerlerle karşılaştırıldı. Yapılan ölçümlerin tavsiye edilen değerler ile uyum içerisinde olduğu gözlendi.

Anahtar Kelimeler

PET/CT

Kaynakça

  • KAYNAKLAR 1. Brady, Z., Taylor, M.L., Haynes, M., et al., (2008). The clinical application of PET / CT: a contemporary review, Australas Phys Eng Sci Med, 90-109 p.
  • 2. Bilski, P. (2002). Lithium Fluoride: From LiF:Mg,Ti to LiF:Mg,Cu,P, Radiation Protection Dosimetry, 199-206p.
  • 3. Boellaard, R., O’Doherty, M.J., Weber, W.A., et al., (2010). FDG PET and PET/CT: EANM procedure guidelines for tumour PET imaging: version 1.0. Eur. J. Nucl. Med. Mol. Imag, 37, 181–200.
  • 4. Etard, C., Celier, D., Roch, P., et al., (2012). National survey of patient doses from whole-body FDG PET-CT examinations in France in 2011. Radiat. Prot. Dosimetry, 152, 334–338.
  • 5. Krause, B.J., Beyer, T., Bockisch, A., et al., (2007). FDG-PET/CT in oncology. Nuklearmedizin, 291-301p.
  • 6. MIRD Committee, (2002). MIRD Dose Estimate Report No. 19: Radiation Absorbed Dose Estimates from 18F-FDG, Journal of Nuclear Medicine, 210-214p.
  • 7. Nureg/CR-6345. (1992). Radiation Dose Estimates for Radiopharmaceuticals.
  • 8. ICRP 53, (2001). Addendum 5, 6 and 7 Radiation Dose to Patients from Radiopharmaceuticals ICRP-53 Interim report, October.
  • 9. Savaş, R. PET/BT nedir, endikasyonları nelerdir?http://www.klinikgelisim.org.tr/kg23 2/8.pdf (Erişim Tarihi: 05.01.2020).
  • 10. Sharon F. H. (2005). Positron Emission Tomography in Cancer of The Head And Neck, The Institute of Nuclear Medicine, Middlesex Hospital, UCH NHS Trust and Charing Cross Hospital, Hammersmith Hospitals NHS Trust, London WIT 3AA, UK, British Journal of Oral and Maxillofacial Surgery, 43, 1-6.
  • 11. Brix, G., Lechel, U., Glatting, G., Ziegler, S.I., Münzing, W., Muller, S.P. and Beyer T. (2005). Radiation Exposure of Patients Undergoing Whole- Body Dual-Modality 18F-FDG/CT Examinations. Journal of Nuclear Medicine, 46 No.4 pp.608-613.
  • 12. Delbeke, D. (1999). Oncological application of FDG PET imaging, J Nucl Med, 1706-15p.
  • 13. B. Guillet, P. Quentin, S. Waultier, M. Bourrelly, P. Pisano, O. Mundler, 2005. “Technologist radiation exposure in routine clinical practice with 18F-FDG PET”, Journal of Nuclear Medicine Technology, vol.33, No.3, pp.175- 179.
  • 14. D. W. Townsend, 2008. “Positron Emission Tomography/Computed Tomography” Elsevier, vol.38, No. 3, pp. 152-166.
  • 15. J.M.M. Climent, I. Peñuelas., 2001. “Occupational Dosimetry in a Pet Center Due To Radionuclide Production And Medical Use. Nuclear Medicine Service. University Hospital.” University of Navarra. Pamplona. Spain.
  • 16. Huang B, Law M.W, Khong P.L., 2009. Whole-body PET/CT scanning: estimation of radiation dose and cancer risk. Radiology. 251:166-74.
  • 17. Beyer, T., Czernin, J., Freudenberg, L.S., 2011. Variations in clinical PET/CT operations: results of an international survey of active PET/CT users. J. Nucl. Med. 52, 303–310.
  • 18. Recommendations of the International Commission on Radiological Protection. Ann ICRP 1991;21:1-201.
  • 19. Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation, Nuclear and Radiation Studies Board, Division on Earth and Life Studies, National Research Council of the National Academics. Health risks from exposure to low levels of ionizing radiation: BEIR VII Phase 2. Washington, DC: National Academy Press; 2006.
  • 20. De Groot, E.H., Post, N., Boellaard, R., Wagenaar, N.R.L., Willemsen, A.T.M. and Van Dalen, J.A. (2013) Optimized Dose Regimen for Whole-Body FDG-PET Imaging. EJNMMI Research, 63, 1-11. https://doi.org/10.1186/2191-219X-3-63

Yıl 2020, Cilt: 13 Sayı: 1, 58 - 63, 27.07.2020

Turan Şahmaran , Mehmet Bayburt

Öz

Kaynakça

  • KAYNAKLAR 1. Brady, Z., Taylor, M.L., Haynes, M., et al., (2008). The clinical application of PET / CT: a contemporary review, Australas Phys Eng Sci Med, 90-109 p.
  • 2. Bilski, P. (2002). Lithium Fluoride: From LiF:Mg,Ti to LiF:Mg,Cu,P, Radiation Protection Dosimetry, 199-206p.
  • 3. Boellaard, R., O’Doherty, M.J., Weber, W.A., et al., (2010). FDG PET and PET/CT: EANM procedure guidelines for tumour PET imaging: version 1.0. Eur. J. Nucl. Med. Mol. Imag, 37, 181–200.
  • 4. Etard, C., Celier, D., Roch, P., et al., (2012). National survey of patient doses from whole-body FDG PET-CT examinations in France in 2011. Radiat. Prot. Dosimetry, 152, 334–338.
  • 5. Krause, B.J., Beyer, T., Bockisch, A., et al., (2007). FDG-PET/CT in oncology. Nuklearmedizin, 291-301p.
  • 6. MIRD Committee, (2002). MIRD Dose Estimate Report No. 19: Radiation Absorbed Dose Estimates from 18F-FDG, Journal of Nuclear Medicine, 210-214p.
  • 7. Nureg/CR-6345. (1992). Radiation Dose Estimates for Radiopharmaceuticals.
  • 8. ICRP 53, (2001). Addendum 5, 6 and 7 Radiation Dose to Patients from Radiopharmaceuticals ICRP-53 Interim report, October.
  • 9. Savaş, R. PET/BT nedir, endikasyonları nelerdir?http://www.klinikgelisim.org.tr/kg23 2/8.pdf (Erişim Tarihi: 05.01.2020).
  • 10. Sharon F. H. (2005). Positron Emission Tomography in Cancer of The Head And Neck, The Institute of Nuclear Medicine, Middlesex Hospital, UCH NHS Trust and Charing Cross Hospital, Hammersmith Hospitals NHS Trust, London WIT 3AA, UK, British Journal of Oral and Maxillofacial Surgery, 43, 1-6.
  • 11. Brix, G., Lechel, U., Glatting, G., Ziegler, S.I., Münzing, W., Muller, S.P. and Beyer T. (2005). Radiation Exposure of Patients Undergoing Whole- Body Dual-Modality 18F-FDG/CT Examinations. Journal of Nuclear Medicine, 46 No.4 pp.608-613.
  • 12. Delbeke, D. (1999). Oncological application of FDG PET imaging, J Nucl Med, 1706-15p.
  • 13. B. Guillet, P. Quentin, S. Waultier, M. Bourrelly, P. Pisano, O. Mundler, 2005. “Technologist radiation exposure in routine clinical practice with 18F-FDG PET”, Journal of Nuclear Medicine Technology, vol.33, No.3, pp.175- 179.
  • 14. D. W. Townsend, 2008. “Positron Emission Tomography/Computed Tomography” Elsevier, vol.38, No. 3, pp. 152-166.
  • 15. J.M.M. Climent, I. Peñuelas., 2001. “Occupational Dosimetry in a Pet Center Due To Radionuclide Production And Medical Use. Nuclear Medicine Service. University Hospital.” University of Navarra. Pamplona. Spain.
  • 16. Huang B, Law M.W, Khong P.L., 2009. Whole-body PET/CT scanning: estimation of radiation dose and cancer risk. Radiology. 251:166-74.
  • 17. Beyer, T., Czernin, J., Freudenberg, L.S., 2011. Variations in clinical PET/CT operations: results of an international survey of active PET/CT users. J. Nucl. Med. 52, 303–310.
  • 18. Recommendations of the International Commission on Radiological Protection. Ann ICRP 1991;21:1-201.
  • 19. Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation, Nuclear and Radiation Studies Board, Division on Earth and Life Studies, National Research Council of the National Academics. Health risks from exposure to low levels of ionizing radiation: BEIR VII Phase 2. Washington, DC: National Academy Press; 2006.
  • 20. De Groot, E.H., Post, N., Boellaard, R., Wagenaar, N.R.L., Willemsen, A.T.M. and Van Dalen, J.A. (2013) Optimized Dose Regimen for Whole-Body FDG-PET Imaging. EJNMMI Research, 63, 1-11. https://doi.org/10.1186/2191-219X-3-63
Toplam 20 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Mühendislik
Bölüm Araştırma Makalesi
Yazarlar

Turan Şahmaran

Mehmet Bayburt Bu kişi benim

Gönderilme Tarihi 13 Şubat 2020
Yayımlanma Tarihi 27 Temmuz 2020
Yayımlandığı Sayı Yıl 2020 Cilt: 13 Sayı: 1

Kaynak Göster

APA Şahmaran, T., & Bayburt, M. (2020). Pozitron Emisyon Tomografi – Bilgisayar Tomografi (Pet - Bt) Uygulamalarında Hastanın Aldığı Radyasyon Dozunun Belirlenmesi. Kafkas Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 13(1), 58-63.