A Case Of Recurrent Odontogenic Myxoma Of The Mandible: Clinical And Radiographic Diagnosis With Review Of Literature

Öz

Odontogenic myxomas are benign tumors of ectomesenchymal origin and comprise of 3%-8% of all odontogenic tumors. They may be derived from cells of the dental follicle, dental papilla or periodontal ligament. Most of the tumors occur in the second to third decades of life and show a marked female predilection. They occur in the premolar-molar region of both jaws but show a preference to the mandible over the maxilla. Radiographically they may be identified due to their characteristic ‘tennis racquet’ appearance although other radiographic forms such as soap-bubble, honeycomb or wispy lace-like trabeculae also exist. Histological appearance of a myxoid stroma made up of 80% hyaluronic acid and 20% chondroitin sulphate with collagen fibres and spindle shaped fibroblasts is distinctive. Owing to the absence of a capsule and the gelatinous nature of the ground substance, a high degree of recurrence is seen especially in tumors that are conservatively managed. Therefore adequate surgical resection with other modes of tissue destruction such as cryotherapy should be followed. Long term follow-up with radiologic surveillance is advocated in order to recognize a possible recurrence and prevent massive tissue destruction and its associated morbidity.

Anahtar Kelimeler

• Myxoma,Odontogenic,tumor

Kaynakça

1. Singaraju S, Wanjari SP, Parwani RN. Odontogenic myxoma of the maxilla: A report of a rare case and review of the literature. J Oral Maxillofac Pathol 2010; 14:19-23.
2. Leiser Y, Abu-El-Naaj I, Peled M. Odontogenic myxoma- A case series and review of the surgical management. J Craniomaxillofac Surg 2009; 37:206-9.
3. Mayrink G, Luna AH, Olate S, Asprino L, De Moraes M. Surgical treatment of odontogenic myxoma and facial deformity in the same procedure. Contemp Clin Dent 2013; 4:390-2.
4. Landa LE, Hedrick MH, Nepomuceno-Perez MC. Recurrent Myxoma of the Zygoma: A case report. J Oral Maxillofac Surg 2002; 60:704-8.
5. Farman AG, Nortjé CJ, Grotepass FW, Farman FJ, Van Zyl JA. Myxofibroma of the jaws. Br J Oral Surg 1977; 15:3-18.
6. Jindwani K, Nevaskar V, Agrawal D. Odontogenic Myxoma of Maxilla: Management and follow-up of a rare case. Indian Journal of Clinical Practice 2013; 24:130-7.
7. Manne RK, Kumar VS, Sarath VP, Anumula L, Mundlapudi S, Tanikonda R. Odontogenic myxoma of the mandible. Case Rep Dent 2012; 2012:214704.
8. Ayranci F, Ömezli MM, Rastgeldi OZ, Duman A. Odontogenic myxoma located in the mandible: A case report. Middle Black Sea Journal of Health Science 2015; 1:25-8.

9. Regezi JA, Kerr DA, Courtney RM. Odontogenic tumors: Analysis of 706 cases. J Oral Surg 1978; 36:771-8.
10. Gomes CC, Diniz MG, Duarte AP, Bernardes VF, Gomez RS. Molecular review of odontogenic myxoma. Oral Oncol 2011; 47:325-8.
11. Nitzan DW, Gazit D, Azaz B. Childhood odontogenic myxoma: Report of two cases. Pediatr Dent 1985; 7:140-4.
12. Sivakumar G, Kavitha B, Saraswathi TR, Sivapathasundharam B. Odontogenic myxoma of maxilla. Indian J Dent Res 2008; 19:62–5.
13. Spencer KR, Smith A. Odontogenic myxoma: Case report with reconstructive considerations. Aust Dent J 1998; 43:209-12.
14. Andrade FR, Sousa DP, Mendonca EF, Silva TA, Lara VS, Batista AC. Expression of bone resorption regulators (RANK, RANKL, and OPG) in odontogenic tumors. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008; 106:548–55.
15. Asaumi J, Konouchi H, Hisatomi M, Kishi K. Odontogenic myxoma of maxillary sinus: CT and MR- Pathologic correlation. Eur J Radiol 2001; 37:1-4.
16. Jewer DD, Boyd JB, Manktelow RT, Zuker RM, Rosen IB, Gullane PJ, Rotstein LE, Freeman JE. Orofacial and mandibular reconstruction with the iliac crest free flap: A review of 60 cases and a new method of classification. Plast Reconstr Surg 1989; 84:391-403.